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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
8.5 DPC

15 matching records from 15 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Ascl2  achaete-scute family bHLH transcription factor 2   (Synonyms: 2410083I15Rik, bHLHa45, Mash2)
Results  Reference
1J:314901 Bao H, Liu D, Xu Y, Sun Y, Mu C, Yu Y, Wang C, Han Q, Liu S, Cai H, Liu F, Kong S, Deng W, Cao B, Wang H, Wang Q, Lu J, Hyperactivated Wnt-beta-catenin signaling in the absence of sFRP1 and sFRP5 disrupts trophoblast differentiation through repression of Ascl2. BMC Biol. 2020 Oct 27;18(1):151
1J:64703 Cocchia M, Huber R, Pantano S, Chen EY, Ma P, Forabosco A, Ko MS, Schlessinger D, PLAC1, an Xq26 gene with placenta-specific expression. Genomics. 2000 Sep 15;68(3):305-12
1*J:81004 Finkenzeller D, Fischer B, Lutz S, Schrewe H, Shimizu T, Zimmermann W, Carcinoembryonic antigen-related cell adhesion molecule 10 expressed specifically early in pregnancy in the decidua is dispensable for normal murine development. Mol Cell Biol. 2003 Jan;23(1):272-9
1*J:23260 Guillemot F, Caspary T, Tilghman SM, Copeland NG, Gilbert DJ, Jenkins NA, Anderson DJ, Joyner AL, Rossant J, Nagy A, Genomic imprinting of Mash2, a mouse gene required for trophoblast development. Nat Genet. 1995 Mar;9(3):235-42
1*J:20553 Guillemot F, Nagy A, Auerbach A, Rossant J, Joyner AL, Essential role of Mash-2 in extraembryonic development. Nature. 1994 Sep 22;371(6495):333-6
1J:202357 Hu D, Scott IC, Snider F, Geary-Joo C, Zhao X, Simmons DG, Cross JC, The basic helix-loop-helix transcription factor Hand1 regulates mouse development as a homodimer. Dev Biol. 2013 Oct 15;382(2):470-81
1*J:42488 Luo J, Sladek R, Bader JA, Matthyssen A, Rossant J, Giguere V, Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-beta. Nature. 1997 Aug 21;388(6644):778-82
1*J:87675 Moser M, Li Y, Vaupel K, Kretzschmar D, Kluge R, Glynn P, Buettner R, Placental failure and impaired vasculogenesis result in embryonic lethality for neuropathy target esterase-deficient mice. Mol Cell Biol. 2004 Feb;24(4):1667-79
1J:42726 Nakayama H, Liu Y, Stifani S, Cross JC, Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway. Dev Genet. 1997;21(1):21-30
1*J:48573 Nakayama H, Scott IC, Cross JC, The transition to endoreduplication in trophoblast giant cells is regulated by the mSNA zinc finger transcription factor. Dev Biol. 1998 Jul 1;199(1):150-63
1J:71583 Parr BA, Cornish VA, Cybulsky MI, McMahon AP, Wnt7b regulates placental development in mice. Dev Biol. 2001 Sep 15;237(2):324-32
1J:198710 Plaks V, Rinkenberger J, Dai J, Flannery M, Sund M, Kanasaki K, Ni W, Kalluri R, Werb Z, Matrix metalloproteinase-9 deficiency phenocopies features of preeclampsia and intrauterine growth restriction. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11109-14
1*J:48170 Rossant J, Guillemot F, Tanaka M, Latham K, Gertenstein M, Nagy A, Mash2 is expressed in oogenesis and preimplantation development but is not required for blastocyst formation. Mech Dev. 1998 May;73(2):183-91
1J:335660 Scott IC, Anson-Cartwright L, Riley P, Reda D, Cross JC, The HAND1 basic helix-loop-helix transcription factor regulates trophoblast differentiation via multiple mechanisms. Mol Cell Biol. 2000 Jan;20(2):530-41
1*J:57828 Tanaka M, Puchyr M, Gertsenstein M, Harpal K, Jaenisch R, Rossant J, Nagy A, Parental origin-specific expression of Mash2 is established at the time of implantation with its imprinting mechanism highly resistant to genome-wide demethylation. Mech Dev. 1999 Sep;87(1-2):129-42

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory