Gene Expression Literature Summary

Assay

Age

In situ RNA (whole mount)

7.5 DPC

20 matching records from 20 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Wnt3 wingless-type MMTV integration site family, member 3 (Synonyms: Int-4, Wnt-3)
Results	Reference
1	J:311976 Ajima R, Sakakibara Y, Sakurai-Yamatani N, Muraoka M, Saga Y, Formal proof of the requirement of MESP1 and MESP2 in mesoderm specification and their transcriptional control via specific enhancers in mice. Development. 2021 Oct 15;148(20):dev194613
1	J:290418 Ashokkumar D, Zhang Q, Much C, Bledau AS, Naumann R, Alexopoulou D, Dahl A, Goveas N, Fu J, Anastassiadis K, Stewart AF, Kranz A, MLL4 is required after implantation, whereas MLL3 becomes essential during late gestation. Development. 2020 Jun 17;147(12):dev186999
1	J:130205 Barrow JR, Howell WD, Rule M, Hayashi S, Thomas KR, Capecchi MR, McMahon AP, Wnt3 signaling in the epiblast is required for proper orientation of the anteroposterior axis. Dev Biol. 2007 Dec 1;312(1):312-20
1	J:254597 Bhargava S, Cox B, Polydorou C, Gresakova V, Korinek V, Strnad H, Sedlacek R, Epp TA, Chawengsaksophak K, The epigenetic modifier Fam208a is required to maintain epiblast cell fitness. Sci Rep. 2017 Aug 24;7(1):9322
1*	J:198636 Biechele S, Cockburn K, Lanner F, Cox BJ, Rossant J, Porcn-dependent Wnt signaling is not required prior to mouse gastrulation. Development. 2013 Jul;140(14):2961-71
1*	J:173623 Biechele S, Cox BJ, Rossant J, Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos. Dev Biol. 2011 Jul 15;355(2):275-85
1	J:239417 Dai HQ, Wang BA, Yang L, Chen JJ, Zhu GC, Sun ML, Ge H, Wang R, Chapman DL, Tang F, Sun X, Xu GL, TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling. Nature. 2016 Oct 27;538(7626):528-532
1*	J:165751 Du J, Takeuchi H, Leonhard-Melief C, Shroyer KR, Dlugosz M, Haltiwanger RS, Holdener BC, O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation. Dev Biol. 2010 Oct 1;346(1):25-38
1	J:154679 Fu J, Jiang M, Mirando AJ, Yu HM, Hsu W, Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18598-603
1	J:82316 Hsieh JC, Lee L, Zhang L, Wefer S, Brown K, DeRossi C, Wines ME, Rosenquist T, Holdener BC, Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity. Cell. 2003 Feb 7;112(3):355-67
1	J:91055 Kelly OG, Pinson KI, Skarnes WC, The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice. Development. 2004 Jun;131(12):2803-15
1	J:74124 Kinder SJ, Tsang TE, Ang SL, Behringer RR, Tam PP, Defects of the body plan of mutant embryos lacking Lim1, Otx2 or Hnf3beta activity. Int J Dev Biol. 2001;45(1 Spec No):347-55
1*	J:199577 Kitajima K, Oki S, Ohkawa Y, Sumi T, Meno C, Wnt signaling regulates left-right axis formation in the node of mouse embryos. Dev Biol. 2013 Aug 15;380(2):222-32
1	J:134688 Lewis SL, Khoo PL, De Young RA, Steiner K, Wilcock C, Mukhopadhyay M, Westphal H, Jamieson RV, Robb L, Tam PP, Dkk1 and Wnt3 interact to control head morphogenesis in the mouse. Development. 2008 May;135(10):1791-801
1	J:176435 Mesnard D, Donnison M, Fuerer C, Pfeffer PL, Constam DB, The microenvironment patterns the pluripotent mouse epiblast through paracrine Furin and Pace4 proteolytic activities. Genes Dev. 2011 Sep 1;25(17):1871-80
1*	J:236404 Minocha S, Bessonnard S, Sung TL, Moret C, Constam DB, Herr W, Epiblast-specific loss of HCF-1 leads to failure in anterior-posterior axis specification. Dev Biol. 2016 Oct 1;418(1):75-88
1	J:177114 Miura S, Mishina Y, Hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs) is involved in BMP signaling through phosphorylation of smads and TAK1 in early mouse embryo. Dev Dyn. 2011 Nov;240(11):2474-81
1	J:171680 Stuckey DW, Di Gregorio A, Clements M, Rodriguez TA, Correct patterning of the primitive streak requires the anterior visceral endoderm. PLoS One. 2011;6(3):e17620
1	J:199855 Tanaka SS, Nakane A, Yamaguchi YL, Terabayashi T, Abe T, Nakao K, Asashima M, Steiner KA, Tam PP, Nishinakamura R, Dullard/Ctdnep1 modulates WNT signalling activity for the formation of primordial germ cells in the mouse embryo. PLoS One. 2013;8(3):e57428
1*	J:138922 Uez N, Lickert H, Kohlhase J, de Angelis MH, Kuhn R, Wurst W, Floss T, Sall4 isoforms act during proximal-distal and anterior-posterior axis formation in the mouse embryo. Genesis. 2008 Sep 9;46(9):463-477

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/28/2024 MGI 6.13