Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nanog  Nanog homeobox   (Synonyms: 2410002E02Rik, ecat4, ENK)
Results	Reference
1	J:195303 Aksoy I, Jauch R, Chen J, Dyla M, Divakar U, Bogu GK, Teo R, Leng Ng CK, Herath W, Lili S, Hutchins AP, Robson P, Kolatkar PR, Stanton LW, Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm. EMBO J. 2013 Apr 3;32(7):938-53
1	J:326354 Allegre N, Chauveau S, Dennis C, Renaud Y, Meistermann D, Estrella LV, Pouchin P, Cohen-Tannoudji M, David L, Chazaud C, NANOG initiates epiblast fate through the coordination of pluripotency genes expression. Nat Commun. 2022 Jun 21;13(1):3550
1	J:219394 Boroviak T, Loos R, Bertone P, Smith A, Nichols J, The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. Nat Cell Biol. 2014 Jun;16(6):516-28
1	J:203762 Burton A, Muller J, Tu S, Padilla-Longoria P, Guccione E, Torres-Padilla ME, Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo. Cell Rep. 2013 Nov 14;5(3):687-701
1*	J:124183 Cheng WC, Hsieh-Li HM, Yeh YJ, Li H, Mice lacking the Obox6 homeobox gene undergo normal early embryonic development and are fertile. Dev Dyn. 2007 Sep;236(9):2636-42
1*	J:138685 de Vries WN, Evsikov AV, Brogan LJ, Anderson CP, Graber JH, Knowles BB, Solter D, Reprogramming and differentiation in mammals: motifs and mechanisms. Cold Spring Harb Symp Quant Biol. 2008;73:33-8
1	J:199467 Do DV, Ueda J, Messerschmidt DM, Lorthongpanich C, Zhou Y, Feng B, Guo G, Lin PJ, Hossain MZ, Zhang W, Moh A, Wu Q, Robson P, Ng HH, Poellinger L, Knowles BB, Solter D, Fu XY, A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo. Genes Dev. 2013 Jun 15;27(12):1378-90
1*	J:134633 Gao X, Tate P, Hu P, Tjian R, Skarnes WC, Wang Z, ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6656-61
1*	J:234408 Goolam M, Scialdone A, Graham SJ, Macaulay IC, Jedrusik A, Hupalowska A, Voet T, Marioni JC, Zernicka-Goetz M, Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos. Cell. 2016 Mar 24;165(1):61-74
1*	J:90050 Hart AH, Hartley L, Ibrahim M, Robb L, Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human. Dev Dyn. 2004 May;230(1):187-98
1*	J:95814 Hatano SY, Tada M, Kimura H, Yamaguchi S, Kono T, Nakano T, Suemori H, Nakatsuji N, Tada T, Pluripotential competence of cells associated with Nanog activity. Mech Dev. 2005 Jan;122(1):67-79
1*	J:189008 Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK, Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207
1*	J:118937 Kaji K, Nichols J, Hendrich B, Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. Development. 2007 Mar;134(6):1123-32
1	J:234323 Kurian L, Aguirre A, Sancho-Martinez I, Benner C, Hishida T, Nguyen TB, Reddy P, Nivet E, Krause MN, Nelles DA, Esteban CR, Campistol JM, Yeo GW, Belmonte JCI, Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development. Circulation. 2015 Apr 7;131(14):1278-1290
1	J:185350 Lavial F, Bessonnard S, Ohnishi Y, Tsumura A, Chandrashekran A, Fenwick MA, Tomaz RA, Hosokawa H, Nakayama T, Chambers I, Hiiragi T, Chazaud C, Azuara V, Bmi1 facilitates primitive endoderm formation by stabilizing Gata6 during early mouse development. Genes Dev. 2012 Jul 1;26(13):1445-58
1*	J:243694 Li L, Walsh RM, Wagh V, James MF, Beauchamp RL, Chang YS, Gusella JF, Hochedlinger K, Ramesh V, Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency. PLoS One. 2015;10(10):e0140192
1*	J:329326 Marta C, Dawid W, Silvestre S, Pawel G, Salvatore P, Modlinski JA, Pasqualino L, Mitochondrial function and intracellular distribution is severely affected in in vitro cultured mouse embryos. Sci Rep. 2022 Sep 27;12(1):16152
1*	J:182713 McDonel P, Demmers J, Tan DW, Watt F, Hendrich BD, Sin3a is essential for the genome integrity and viability of pluripotent cells. Dev Biol. 2012 Mar 1;363(1):62-73
1	J:310907 Nacarino-Palma A, Gonzalez-Rico FJ, Rejano-Gordillo CM, Ordiales-Talavero A, Merino JM, Fernandez-Salguero PM, The aryl hydrocarbon receptor promotes differentiation during mouse preimplantational embryo development. Stem Cell Reports. 2021 Sep 14;16(9):2351-2363
1	J:172167 Rieger C, Poppino R, Sheridan R, Moley K, Mitra R, Gottlieb D, Polony analysis of gene expression in ES cells and blastocysts. Nucleic Acids Res. 2007;35(22):e151
1	J:204480 Saha B, Home P, Ray S, Larson M, Paul A, Rajendran G, Behr B, Paul S, EED and KDM6B coordinate the first mammalian cell lineage commitment to ensure embryo implantation. Mol Cell Biol. 2013 Jul;33(14):2691-705
1	J:159743 Saito K, Abe H, Nakazawa M, Irokawa E, Watanabe M, Hosoi Y, Soma M, Kasuga K, Kojima I, Kobayashi M, Cloning of complementary DNAs encoding structurally related homeoproteins from preimplantation mouse embryos: their involvement in the differentiation of embryonic stem cells. Biol Reprod. 2010 Apr;82(4):687-97
1	J:165572 Sebastiano V, Dalvai M, Gentile L, Schubart K, Sutter J, Wu GM, Tapia N, Esch D, Ju JY, Hubner K, Bravo MJ, Scholer HR, Cavaleri F, Matthias P, Oct1 regulates trophoblast development during early mouse embryogenesis. Development. 2010 Nov;137(21):3551-60
1	J:266780 Watanabe Y, Miyasaka KY, Kubo A, Kida YS, Nakagawa O, Hirate Y, Sasaki H, Ogura T, Notch and Hippo signaling converge on Strawberry Notch 1 (Sbno1) to synergistically activate Cdx2 during specification of the trophectoderm. Sci Rep. 2017 Apr 12;7:46135
1	J:201607 Wu G, Han D, Gong Y, Sebastiano V, Gentile L, Singhal N, Adachi K, Fischedick G, Ortmeier C, Sinn M, Radstaak M, Tomilin A, Scholer HR, Establishment of totipotency does not depend on Oct4A. Nat Cell Biol. 2013 Sep;15(9):1089-97
1	J:212567 Yin S, Wu H, Lv J, Wu X, Zhang Y, Du J, Zhang Y, SHP-1 arrests mouse early embryo development through downregulation of Nanog by dephosphorylation of STAT3. PLoS One. 2014;9(1):e86330