Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Neurog3  neurogenin 3   (Synonyms: Atoh5, bHLHa7, Math4B, ngn3)
Results	Reference
1	J:338878 Abarinov V, Levine JA, Churchill AJ, Hopwood B, Deiter CS, Guney MA, Wells KL, Schrunk JM, Guo Y, Hammelman J, Gifford DK, Magnuson MA, Wichterle H, Sussel L, Major beta cell-specific functions of NKX2.2 are mediated via the NK2-specific domain. Genes Dev. 2023 Jun 1;37(11-12):490-504
1	J:156022 Anderson KR, White P, Kaestner KH, Sussel L, Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development. BMC Dev Biol. 2009;9:65
1	J:190582 Bondow BJ, Faber ML, Wojta KJ, Walker EM, Battle MA, E-cadherin is required for intestinal morphogenesis in the mouse. Dev Biol. 2012 Nov 1;371(1):1-12
1	J:240413 Churchill AJ, Gutierrez GD, Singer RA, Lorberbaum DS, Fischer KA, Sussel L, Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development. Elife. 2017 Jan 10;6:e20010
1	J:108241 Desai J, Shannon ME, Johnson MD, Ruff DW, Hughes LA, Kerley MK, Carpenter DA, Johnson DK, Rinchik EM, Culiat CT, Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Hum Mol Genet. 2006 Apr 15;15(8):1329-41
1	J:332289 Dobosz AM, Janikiewicz J, Krogulec E, Dziewulska A, Ajduk A, Szpila M, Nieznanska H, Szczepankiewicz AA, Wypych D, Dobrzyn A, Inhibition of stearoyl-CoA desaturase 1 in the mouse impairs pancreatic islet morphogenesis and promotes loss of beta-cell identity and alpha-cell expansion in the mature pancreas. Mol Metab. 2022 Dec 15;67:101659
1*	J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
1	J:208600 Hunter CS, Dixit S, Cohen T, Ediger B, Wilcox C, Ferreira M, Westphal H, Stein R, May CL, Islet alpha-, beta-, and delta-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor. Diabetes. 2013 Mar;62(3):875-86
1	J:137419 Kajino-Sakamoto R, Inagaki M, Lippert E, Akira S, Robine S, Matsumoto K, Jobin C, Ninomiya-Tsuji J, Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis. J Immunol. 2008 Jul 15;181(2):1143-52
1	J:214095 Osipovich AB, Long Q, Manduchi E, Gangula R, Hipkens SB, Schneider J, Okubo T, Stoeckert CJ Jr, Takada S, Magnuson MA, Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3. Development. 2014 Aug;141(15):2939-49
1*	J:241573 Pui HP, Saga Y, Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. Mech Dev. 2017 Apr;144(Pt B):125-139
1	J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7
1	J:164654 Valtat B, Dupuis C, Zenaty D, Singh-Estivalet A, Tronche F, Breant B, Blondeau B, Genetic evidence of the programming of beta cell mass and function by glucocorticoids in mice. Diabetologia. 2011 Feb;54(2):350-9
1	J:165742 VanDussen KL, Samuelson LC, Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate. Dev Biol. 2010 Oct 15;346(2):215-23
1	J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94
1	J:150074 Wang S, Jensen JN, Seymour PA, Hsu W, Dor Y, Sander M, Magnuson MA, Serup P, Gu G, Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9715-20