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Gene Expression Literature Summary
Assay
Age
RT-PCR
18.5 DPC

19 matching records from 19 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Sox2  SRY (sex determining region Y)-box 2   (Synonyms: lcc, Sox-2, ysb)
Results  Reference
1J:237426 Boucherat O, Landry-Truchon K, Aoidi R, Houde N, Nadeau V, Charron J, Jeannotte L, Lung development requires an active ERK/MAPK pathway in the lung mesenchyme. Dev Dyn. 2017 Jan;246(1):72-82
1J:218288 Falcone C, Filippis C, Granzotto M, Mallamaci A, Emx2 expression levels in NSCs modulate astrogenesis rates by regulating EgfR and Fgf9. Glia. 2015 Mar;63(3):412-22
1J:323615 Fu Y, Zhou Y, Zhang YL, Zhao B, Zhang XL, Zhang WT, Lu YJ, Lu A, Zhang J, Zhang J, Loss of neurodevelopmental-associated miR-592 impairs neurogenesis and causes social interaction deficits. Cell Death Dis. 2022 Apr 1;13(4):292
1J:136180 Gontan C, de Munck A, Vermeij M, Grosveld F, Tibboel D, Rottier R, Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation. Dev Biol. 2008 May 1;317(1):296-309
1J:157954 Grainger S, Savory JG, Lohnes D, Cdx2 regulates patterning of the intestinal epithelium. Dev Biol. 2010 Mar 1;339(1):155-65
1J:240480 Kapali J, Kabat BE, Schmidt KL, Stallings CE, Tippy M, Jung DO, Edwards BS, Nantie LB, Raeztman LT, Navratil AM, Ellsworth BS, Foxo1 Is Required for Normal Somatotrope Differentiation. Endocrinology. 2016 Nov;157(11):4351-4363
1J:327969 Khattar D, Fernandes S, Snowball J, Guo M, Gillen MC, Jain SS, Sinner D, Zacharias W, Swarr DT, PI3K signaling specifies proximal-distal fate by driving a developmental gene regulatory network in SOX9+ mouse lung progenitors. Elife. 2022 Aug 17;11:e67954
1J:146694 Lin YP, Ouchi Y, Satoh S, Watanabe S, Sox2 plays a role in the induction of amacrine and Muller glial cells in mouse retinal progenitor cells. Invest Ophthalmol Vis Sci. 2009 Jan;50(1):68-74
1*J:84446 Lioubinski O, Muller M, Wegner M, Sander M, Expression of Sox transcription factors in the developing mouse pancreas. Dev Dyn. 2003 Jul;227(3):402-8
1J:334074 McCoy AM, Lakhdari O, Shome S, Caoili K, Hernandez GE, Aghaeepour N, Butcher LD, Fisch K, Prince LS, Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development. Development. 2023 Mar 1;150(5):dev200839
1J:173578 Parker MA, Jiang K, Kempfle JS, Mizutari K, Simmons CL, Bieber R, Adams J, Edge AS, TAK1 Expression in the Cochlea: A Specific Marker for Adult Supporting Cells. J Assoc Res Otolaryngol. 2011 Aug;12(4):471-83
1J:234328 Perez Millan MI, Brinkmeier ML, Mortensen AH, Camper SA, PROP1 triggers epithelial-mesenchymal transition-like process in pituitary stem cells. Elife. 2016;5:e14470
1J:183888 Roos AB, Berg T, Barton JL, Didon L, Nord M, Airway epithelial cell differentiation during lung organogenesis requires C/EBPalpha and C/EBPbeta. Dev Dyn. 2012 May;241(5):911-23
1J:204277 Sauvageau M, Goff LA, Lodato S, Bonev B, Groff AF, Gerhardinger C, Sanchez-Gomez DB, Hacisuleyman E, Li E, Spence M, Liapis SC, Mallard W, Morse M, Swerdel MR, D'Ecclessis MF, Moore JC, Lai V, Gong G, Yancopoulos GD, Frendewey D, Kellis M, Hart RP, Valenzuela DM, Arlotta P, Rinn JL, Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Elife. 2013;2(0):e01749
1J:267193 Sun Z, da Fontoura CSG, Moreno M, Holton NE, Sweat M, Sweat Y, Lee MK, Arbon J, Bidlack FB, Thedens DR, Nopoulos P, Cao H, Eliason S, Weinberg SM, Martin JF, Moreno-Uribe L, Amendt BA, FoxO6 regulates Hippo signaling and growth of the craniofacial complex. PLoS Genet. 2018 Oct;14(10):e1007675
1J:270543 Tanahashi H, Suzuki T, Deletion of Lrp4 increases the incidence of microphthalmia. Biochem Biophys Res Commun. 2018 Nov 30;506(3):478-484
1J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45
1J:341147 Young RE, Jones MK, Hines EA, Li R, Luo Y, Shi W, Verheyden JM, Sun X, Smooth Muscle Differentiation Is Essential for Airway Size, Tracheal Cartilage Segmentation, but Dispensable for Epithelial Branching. Dev Cell. 2020 Apr 6;53(1):73-85.e5
1*J:187393 Zhang L, Yuan G, Liu H, Lin H, Wan C, Chen Z, Expression pattern of Sox2 during mouse tooth development. Gene Expr Patterns. 2012 Aug;12(7-8):273-81

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory