About   Help   FAQ
Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (whole mount)
18.5 DPC

18 matching records from 18 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Myo7a  myosin VIIA   (Synonyms: Hdb, Myo7, nmf371, polka, USH1B)
Results  Reference
1*J:181471 Ahmed M, Wong EY, Sun J, Xu J, Wang F, Xu PX, Eya1-six1 interaction is sufficient to induce hair cell fate in the cochlea by activating atoh1 expression in cooperation with sox2. Dev Cell. 2012 Feb 14;22(2):377-90
1J:274580 Bademci G, Abad C, Incesulu A, Elian F, Reyahi A, Diaz-Horta O, Cengiz FB, Sineni CJ, Seyhan S, Atli EI, Basmak H, Demir S, Nik AM, Footz T, Guo S, Duman D, Fitoz S, Gurkan H, Blanton SH, Walter MA, Carlsson P, Walz K, Tekin M, FOXF2 is required for cochlear development in humans and mice. Hum Mol Genet. 2019 Apr 15;28(8):1286-1297
1J:306028 Chen T, Rohacek AM, Caporizzo M, Nankali A, Smits JJ, Oostrik J, Lanting CP, Kucuk E, Gilissen C, van de Kamp JM, Pennings RJE, Rakowiecki SM, Kaestner KH, Ohlemiller KK, Oghalai JS, Kremer H, Prosser BL, Epstein DJ, Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing. Dev Cell. 2021 May 17;56(10):1526-1540.e7
1J:253766 Dvorakova M, Jahan I, Macova I, Chumak T, Bohuslavova R, Syka J, Fritzsch B, Pavlinkova G, Incomplete and delayed Sox2 deletion defines residual ear neurosensory development and maintenance. Sci Rep. 2016 Dec 5;6:38253
1J:340392 Ebeid M, Kishimoto I, Roy P, Zaidi MAA, Cheng AG, Huh SH, beta-Catenin transcriptional activity is required for establishment of inner pillar cell identity during cochlear development. PLoS Genet. 2023 Aug;19(8):e1010925
1J:321815 Filova I, Bohuslavova R, Tavakoli M, Yamoah EN, Fritzsch B, Pavlinkova G, Early Deletion of Neurod1 Alters Neuronal Lineage Potential and Diminishes Neurogenesis in the Inner Ear. Front Cell Dev Biol. 2022;10:845461
1J:290788 Gnedeva K, Wang X, McGovern MM, Barton M, Tao L, Trecek T, Monroe TO, Llamas J, Makmura W, Martin JF, Groves AK, Warchol M, Segil N, Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal. Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13552-13561
1J:262601 Huang Y, Hill J, Yatteau A, Wong L, Jiang T, Petrovic J, Gan L, Dong L, Wu DK, Reciprocal Negative Regulation Between Lmx1a and Lmo4 Is Required for Inner Ear Formation. J Neurosci. 2018 Jun 6;38(23):5429-5440
1J:306218 Landin Malt A, Hogan AK, Smith CD, Madani MS, Lu X, Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling. J Cell Biol. 2020 Oct 5;219(10)
1J:135991 Lefevre G, Michel V, Weil D, Lepelletier L, Bizard E, Wolfrum U, Hardelin JP, Petit C, A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth. Development. 2008 Apr;135(8):1427-37
1J:333966 Nagaoka T, Katsuno T, Fujimura K, Tsuchida K, Kishi M, Functional interaction between Vangl2 and N-cadherin regulates planar cell polarization of the developing neural tube and cochlear sensory epithelium. Sci Rep. 2023 Mar 8;13(1):3905
1J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981
1J:285992 Ono K, Keller J, Lopez Ramirez O, Gonzalez Garrido A, Zobeiri OA, Chang HHV, Vijayakumar S, Ayiotis A, Duester G, Della Santina CC, Jones SM, Cullen KE, Eatock RA, Wu DK, Retinoic acid degradation shapes zonal development of vestibular organs and sensitivity to transient linear accelerations. Nat Commun. 2020 Jan 2;11(1):63
1J:335097 Qin T, Ho CC, Wang B, Hui CC, Sham MH, Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2206571119
1J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5
1J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175
1*J:311142 Sun H, Wang T, Atkinson PJ, Billings SE, Dong W, Cheng AG, Gpr125 Marks Distinct Cochlear Cell Types and Is Dispensable for Cochlear Development and Hearing. Front Cell Dev Biol. 2021;9:690955
1*J:239360 Zhang Y, Chen Y, Ni W, Guo L, Lu X, Liu L, Li W, Sun S, Wang L, Li H, Dynamic expression of Lgr6 in the developing and mature mouse cochlea. Front Cell Neurosci. 2015;9:165

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/14/2024
MGI 6.23
The Jackson Laboratory