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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
18.5 DPC

8 matching records from 8 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Pitx2  paired-like homeodomain transcription factor 2   (Synonyms: Brx1, Brx1a, Brx1b, Munc30, Otlx2, Pitx2a, Pitx2b, Pitx2c, Ptx2, Rieg, solurshin)
Results  Reference
1*J:157799 Acharya M, Lingenfelter DJ, Huang L, Gage PJ, Walter MA, Human PRKC apoptosis WT1 regulator is a novel PITX2-interacting protein that regulates PITX2 transcriptional activity in ocular cells. J Biol Chem. 2009 Dec 11;284(50):34829-38
1J:99227 Charles MA, Suh H, Hjalt TA, Drouin J, Camper SA, Gage PJ, PITX genes are required for cell survival and Lhx3 activation. Mol Endocrinol. 2005 Jul;19(7):1893-903
1*J:130185 Ellsworth BS, Butts DL, Camper SA, Mechanisms underlying pituitary hypoplasia and failed cell specification in Lhx3-deficient mice. Dev Biol. 2008 Jan 1;313(1):118-29
1*J:62068 Hjalt TA, Semina EV, Amendt BA, Murray JC, The Pitx2 protein in mouse development. Dev Dyn. 2000 May;218(1):195-200
1J:240032 Nouri N, Awatramani R, A novel floor plate boundary defined by adjacent En1 and Dbx1 microdomains distinguishes midbrain dopamine and hypothalamic neurons. Development. 2017 Mar 01;144(5):916-927
1J:160534 Ono Y, Nakatani T, Minaki Y, Kumai M, The basic helix-loop-helix transcription factor Nato3 controls neurogenic activity in mesencephalic floor plate cells. Development. 2010 Jun;137(11):1897-906
1J:167837 Waite MR, Skidmore JM, Billi AC, Martin JF, Martin DM, GABAergic and glutamatergic identities of developing midbrain Pitx2 neurons. Dev Dyn. 2011 Feb;240(2):333-46
1J:336860 Wurmser M, Madani R, Chaverot N, Backer S, Borok M, Dos Santos M, Comai G, Tajbakhsh S, Relaix F, Santolini M, Sambasivan R, Jiang R, Maire P, Overlapping functions of SIX homeoproteins during embryonic myogenesis. PLoS Genet. 2023 Jun;19(6):e1010781

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory