Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Krt6  keratin 6   (Synonyms: K6, Krt-2.6, Krt2-6)
Results	Reference
1	J:281201 Anderton H, Bandala-Sanchez E, Simpson DS, Rickard JA, Ng AP, Di Rago L, Hall C, Vince JE, Silke J, Liccardi G, Feltham R, RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development. Cell Death Differ. 2019 May;26(5):877-889
1	J:141601 Bayo P, Sanchis A, Bravo A, Cascallana JL, Buder K, Tuckermann J, Schutz G, Perez P, Glucocorticoid receptor is required for skin barrier competence. Endocrinology. 2008 Mar;149(3):1377-88
1*	J:168020 Boglev Y, Wilanowski T, Caddy J, Parekh V, Auden A, Darido C, Hislop NR, Cangkrama M, Ting SB, Jane SM, The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity. Dev Biol. 2011 Jan 15;349(2):512-22
1	J:233531 Cangkrama M, Darido C, Georgy SR, Partridge D, Auden A, Srivastava S, Wilanowski T, Jane SM, Two Ancient Gene Families Are Critical for Maintenance of the Mammalian Skin Barrier in Postnatal Life. J Invest Dermatol. 2016 Jul;136(7):1438-48
1	J:46989 Celli G, LaRochelle WJ, Mackem S, Sharp R, Merlino G, Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning. EMBO J. 1998 Mar 16;17(6):1642-55
1*	J:217209 Cottle DL, Ursino GM, Ip SC, Jones LK, Ditommaso T, Hacking DF, Mangan NE, Mellett NA, Henley KJ, Sviridov D, Nold-Petry CA, Nold MF, Meikle PJ, Kile BT, Smyth IM, Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis. Hum Mol Genet. 2015 Jan 15;24(2):436-49
1	J:259661 De Groote P, Tran HT, Fransen M, Tanghe G, Urwyler C, De Craene B, Leurs K, Gilbert B, Van Imschoot G, De Rycke R, Guerin CJ, Holland P, Berx G, Vandenabeele P, Lippens S, Vleminckx K, Declercq W, A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes. Cell Death Differ. 2015 Jun;22(6):1012-24
1	J:335805 Deng Z, Butt T, Arhatari BD, Darido C, Auden A, Swaroop D, Partridge DD, Haigh K, Nguyen T, Haigh JJ, Carpinelli MR, Jane SM, Dysregulation of Grainyhead-like 3 expression causes widespread developmental defects. Dev Dyn. 2023 May;252(5):647-667
1	J:225600 Georgy SR, Cangkrama M, Srivastava S, Partridge D, Auden A, Dworkin S, McLean CA, Jane SM, Darido C, Identification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell Carcinoma. J Natl Cancer Inst. 2015 Sep;107(9)
1	J:163218 Gu B, Sun P, Yuan Y, Moraes RC, Li A, Teng A, Agrawal A, Rheaume C, Bilanchone V, Veltmaat JM, Takemaru K, Millar S, Lee EY, Lewis MT, Li B, Dai X, Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol. 2009 Jun 1;185(5):811-26
1	J:135131 Kashiwagi M, Morgan BA, Georgopoulos K, The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development. 2007 Apr;134(8):1571-82
1*	J:238698 Kasparek P, Ileninova Z, Zbodakova O, Kanchev I, Benada O, Chalupsky K, Brattsand M, Beck IM, Sedlacek R, KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype. PLoS Genet. 2017 Jan;13(1):e1006566
1	J:106064 Kobielak A, Fuchs E, Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2322-7
1	J:230728 Kumar V, Bouameur JE, Bar J, Rice RH, Hornig-Do HT, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P, Brazel CB, Heller S, Binder H, Loffler-Wirth H, Seibel P, Magin TM, A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75
1	J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47
1*	J:203995 Lee S, Kong Y, Weatherbee SD, Forward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cells. Dev Biol. 2013 Nov 15;383(2):201-13
1	J:72550 Li C, Guo H, Xu X, Weinberg W, Deng CX, Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning. Dev Dyn. 2001 Nov;222(3):471-83
1	J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68
1*	J:50471 McGowan KM, Coulombe PA, Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development. J Cell Biol. 1998 Oct 19;143(2):469-86
1	J:122660 Moulson CL, Lin MH, White JM, Newberry EP, Davidson NO, Miner JH, Keratinocyte-specific expression of fatty acid transport protein 4 rescues the wrinkle-free phenotype in Slc27a4/Fatp4 mutant mice. J Biol Chem. 2007 May 25;282(21):15912-20
1	J:182928 Nagarajan P, Chin SS, Wang D, Liu S, Sinha S, Garrett-Sinha LA, Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators. J Cell Sci. 2010 Oct 15;123(Pt 20):3566-75
1*	J:242353 Pichery M, Huchenq A, Sandhoff R, Severino-Freire M, Zaafouri S, Opalka L, Levade T, Soldan V, Bertrand-Michel J, Lhuillier E, Serre G, Maruani A, Mazereeuw-Hautier J, Jonca N, PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier. Hum Mol Genet. 2017 May 15;26(10):1787-1800
1	J:201523 Ray S, Foote HP, Lechler T, beta-Catenin protects the epidermis from mechanical stresses. J Cell Biol. 2013 Jul 8;202(1):45-52
1	J:170365 Sanchis A, Bayo P, Sevilla LM, Perez P, Glucocorticoid receptor antagonizes EGFR function to regulate eyelid development. Int J Dev Biol. 2010;54(10):1473-80
1*	J:159506 Sun P, Yuan Y, Li A, Li B, Dai X, Cytokeratin expression during mouse embryonic and early postnatal mammary gland development. Histochem Cell Biol. 2010 Feb;133(2):213-21
1	J:115742 Takabayashi S, Katoh H, A mutant mouse with severe anemia and skin abnormalities controlled by a new allele of the flaky skin (fsn) locus. Exp Anim. 2005 Jul;54(4):339-47
1	J:260842 Urwyler-Rosselet C, Tanghe G, Leurs K, Gilbert B, De Rycke R, De Bruyne M, Lippens S, Bartunkova S, De Groote P, Niessen C, Haftek M, Vandenabeele P, Declercq W, Keratinocyte-Specific Ablation of RIPK4 Allows Epidermal Cornification but Impairs Skin Barrier Formation. J Invest Dermatol. 2018 Jun;138(6):1268-1278
1*	J:294158 Vernersson Lindahl E, Garcia EL, Mills AA, An allelic series of Trp63 mutations defines TAp63 as a modifier of EEC syndrome. Am J Med Genet A. 2013 Aug;161A(8):1961-71
1	J:143315 Wang X, Pasolli HA, Williams T, Fuchs E, AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis. J Cell Biol. 2008 Oct 6;183(1):37-48