Assay
Age
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Immunohistochemistry (section)
17.5 DPC
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Myo7a myosin VIIA (Synonyms: Hdb, Myo7, nmf371, polka, USH1B) | |
Results | Reference |
1* | J:75944 Chen P, Johnson JE, Zoghbi HY, Segil N, The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination. Development. 2002 May;129(10):2495-505 |
1 | J:303536 Cohen R, Amir-Zilberstein L, Hersch M, Woland S, Loza O, Taiber S, Matsuzaki F, Bergmann S, Avraham KB, Sprinzak D, Mechanical forces drive ordered patterning of hair cells in the mammalian inner ear. Nat Commun. 2020 Oct 12;11(1):5137 |
1 | J:232175 Diaz-Horta O, Abad C, Sennaroglu L, Foster J 2nd, DeSmidt A, Bademci G, Tokgoz-Yilmaz S, Duman D, Cengiz FB, Grati M, Fitoz S, Liu XZ, Farooq A, Imtiaz F, Currall BB, Morton CC, Nishita M, Minami Y, Lu Z, Walz K, Tekin M, ROR1 is essential for proper innervation of auditory hair cells and hearing in humans and mice. Proc Natl Acad Sci U S A. 2016 May 24;113(21):5993-8 |
1* | J:218261 Freeman SD, Keino-Masu K, Masu M, Ladher RK, Expression of the heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, in the avian and mammalian inner ear suggests a role for sulfation during inner ear development. Dev Dyn. 2015 Feb;244(2):168-80 |
1 | J:178934 Freyer L, Aggarwal V, Morrow BE, Dual embryonic origin of the mammalian otic vesicle forming the inner ear. Development. 2011 Dec;138(24):5403-14 |
1 | J:330325 Garcia-Anoveros J, Clancy JC, Foo CZ, Garcia-Gomez I, Zhou Y, Homma K, Cheatham MA, Duggan A, Tbx2 is a master regulator of inner versus outer hair cell differentiation. Nature. 2022 May;605(7909):298-303 |
1 | J:227261 Gnedeva K, Hudspeth AJ, SoxC transcription factors are essential for the development of the inner ear. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):14066-71 |
1 | J:117235 Hayashi T, Cunningham D, Bermingham-McDonogh O, Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Dev Dyn. 2007 Feb;236(2):525-33 |
1 | J:306060 Kindt KS, Akturk A, Jarysta A, Day M, Beirl A, Flonard M, Tarchini B, EMX2-GPR156-Galphai reverses hair cell orientation in mechanosensory epithelia. Nat Commun. 2021 May 17;12(1):2861 |
1 | J:160591 Liu Z, Owen T, Zhang L, Zuo J, Dynamic expression pattern of Sonic hedgehog in developing cochlear spiral ganglion neurons. Dev Dyn. 2010 Jun;239(6):1674-83 |
1 | J:202909 Mansour SL, Li C, Urness LD, Genetic rescue of Muenke syndrome model hearing loss reveals prolonged FGF-dependent plasticity in cochlear supporting cell fates. Genes Dev. 2013 Nov 1;27(21):2320-31 |
1* | J:84152 Meunier D, Peters T, Luttges A, Curfs J, Fundele R, Preferential expression of the G90 gene in post-mitotic cells during mouse embryonic development. Anat Embryol (Berl). 2003 Sep;207(2):109-17 |
1 | J:76464 Sahly I, El-Amraoui A, Abitbol M, Petit C, Dufier JL, Expression of myosin VIIA during mouse embryogenesis. Anat Embryol (Berl). 1997 Aug;196(2):159-70 |
1 | J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175 |
1 | J:252116 Sato S, Furuta Y, Kawakami K, Regulation of continuous but complex expression pattern of Six1 during early sensory development. Dev Dyn. 2018 Jan;247(1):250-261 |
1 | J:112461 Tang LS, Alger HM, Pereira FA, COUP-TFI controls Notch regulation of hair cell and support cell differentiation. Development. 2006 Sep;133(18):3683-93 |
1* | J:203658 Yariz KO, Duman D, Seco CZ, Dallman J, Huang M, Peters TA, Sirmaci A, Lu N, Schraders M, Skromne I, Oostrik J, Diaz-Horta O, Young JI, Tokgoz-Yilmaz S, Konukseven O, Shahin H, Hetterschijt L, Kanaan M, Oonk AM, Edwards YJ, Li H, Atalay S, Blanton S, Desmidt AA, Liu XZ, Pennings RJ, Lu Z, Chen ZY, Kremer H, Tekin M, Mutations in OTOGL, encoding the inner ear protein otogelin-like, cause moderate sensorineural hearing loss. Am J Hum Genet. 2012 Nov 2;91(5):872-82 |
1 | J:308134 Yu HV, Tao L, Llamas J, Wang X, Nguyen JD, Trecek T, Segil N, POU4F3 pioneer activity enables ATOH1 to drive diverse mechanoreceptor differentiation through a feed-forward epigenetic mechanism. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2105137118 |
1* | J:64679 Zheng JL, Shou J, Guillemot F, Kageyama R, Gao W, Hes1 is a negative regulator of inner ear hair cell differentiation. Development. 2000 Nov;127(21):4551-60 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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