Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Krt14  keratin 14   (Synonyms: Cytokeratin 14, epidermolysis bullosa simplex, Dowling-Meara, Koebner, K14, Krt-1.14, Krt1-14)
Results	Reference
1*	J:176660 Abler LL, Keil KP, Mehta V, Joshi PS, Schmitz CT, Vezina CM, A high-resolution molecular atlas of the fetal mouse lower urogenital tract. Dev Dyn. 2011 Oct;240(10):2364-77
1	J:238285 Adolphe C, Junker JP, Lyubimova A, van Oudenaarden A, Wainwright B, Patched Receptors Sense, Interpret, and Establish an Epidermal Hedgehog Signaling Gradient. J Invest Dermatol. 2017 Jan;137(1):179-186
1	J:173672 Barrott JJ, Cash GM, Smith AP, Barrow JR, Murtaugh LC, Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome. Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12752-7
1	J:335426 Butera A, Agostini M, Cassandri M, De Nicola F, Fanciulli M, D'Ambrosio L, Falasca L, Nardacci R, Wang L, Piacentini M, Knight RA, Jia W, Sun Q, Shi Y, Wang Y, Candi E, Melino G, ZFP750 affects the cutaneous barrier through regulating lipid metabolism. Sci Adv. 2023 Apr 28;9(17):eadg5423
1*	J:52207 Chiang C, Swan RZ, Grachtchouk M, Bolinger M, Litingtung Y, Robertson EK, Cooper MK, Gaffield W, Westphal H, Beachy PA, Dlugosz AA, Essential role for Sonic hedgehog during hair follicle morphogenesis. Dev Biol. 1999 Jan 1;205(1):1-9
1*	J:142873 Collins CA, Watt FM, Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for beta-catenin and Notch signalling. Dev Biol. 2008 Dec 1;324(1):55-67
1*	J:217209 Cottle DL, Ursino GM, Ip SC, Jones LK, Ditommaso T, Hacking DF, Mangan NE, Mellett NA, Henley KJ, Sviridov D, Nold-Petry CA, Nold MF, Meikle PJ, Kile BT, Smyth IM, Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis. Hum Mol Genet. 2015 Jan 15;24(2):436-49
1	J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60
1	J:269851 Dainichi T, Hayden MS, Park SG, Oh H, Seeley JJ, Grinberg-Bleyer Y, Beck KM, Miyachi Y, Kabashima K, Hashimoto T, Ghosh S, PDK1 Is a Regulator of Epidermal Differentiation that Activates and Organizes Asymmetric Cell Division. Cell Rep. 2016 May 24;15(8):1615-23
1	J:337788 Descovich CP, Lough KJ, Jena A, Wu JJ, Yom J, Spitzer DC, Uppalapati M, Kedziora KM, Williams SE, AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis. Elife. 2023 Apr 5;12
1	J:242729 Ding X, Bloch W, Iden S, Ruegg MA, Hall MN, Leptin M, Partridge L, Eming SA, mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation. Nat Commun. 2016 Oct 27;7:13226
1	J:196515 Fu J, Hsu W, Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis. J Invest Dermatol. 2013 Apr;133(4):890-8
1	J:334122 Glover JD, Sudderick ZR, Shih BB, Batho-Samblas C, Charlton L, Krause AL, Anderson C, Riddell J, Balic A, Li J, Klika V, Woolley TE, Gaffney EA, Corsinotti A, Anderson RA, Johnston LJ, Brown SJ, Wang S, Chen Y, Crichton ML, Headon DJ, The developmental basis of fingerprint pattern formation and variation. Cell. 2023 Mar 2;186(5):940-956.e20
1	J:258233 Guo D, Yuan Z, Ru J, Gu X, Zhang W, Mao F, Ouyang H, Wu K, Liu Y, Liu C, A Spatiotemporal Requirement for Prickle 1-Mediated PCP Signaling in Eyelid Morphogenesis and Homeostasis. Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):952-966
1	J:203056 Hines EA, Jones MK, Verheyden JM, Harvey JF, Sun X, Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19444-9
1	J:118173 Jarvinen E, Salazar-Ciudad I, Birchmeier W, Taketo MM, Jernvall J, Thesleff I, Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18627-32
1	J:83259 Jaubert J, Cheng J, Segre JA, Ectopic expression of kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier. Development. 2003 Jun;130(12):2767-77
1	J:282774 Jia X, Min L, Zhu S, Zhang S, Huang X, Loss of sonic hedgehog gene leads to muscle development disorder and megaesophagus in mice. FASEB J. 2018 Oct;32(10):5703-5715
1*	J:207607 Keil KP, Abler LL, Mehta V, Altmann HM, Laporta J, Plisch EH, Suresh M, Hernandez LL, Vezina CM, DNA methylation of E-cadherin is a priming mechanism for prostate development. Dev Biol. 2014 Mar 15;387(2):142-53
1	J:180837 Kirschner N, Haftek M, Niessen CM, Behne MJ, Furuse M, Moll I, Brandner JM, CD44 regulates tight-junction assembly and barrier function. J Invest Dermatol. 2011 Apr;131(4):932-43
1	J:309667 Kousa YA, Fuller E, Schutte BC, IRF6 and AP2A Interaction Regulates Epidermal Development. J Invest Dermatol. 2018 Dec;138(12):2578-2588
1	J:257613 Kuony A, Michon F, Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation. Front Physiol. 2017;8:739
1*	J:93615 Kurita T, Medina RT, Mills AA, Cunha GR, Role of p63 and basal cells in the prostate. Development. 2004 Oct;131(20):4955-64
1	J:213415 Lee B, Villarreal-Ponce A, Fallahi M, Ovadia J, Sun P, Yu QC, Ito S, Sinha S, Nie Q, Dai X, Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells. Dev Cell. 2014 Apr 14;29(1):47-58
1	J:301558 Lee DH, Olson AW, Wang J, Kim WK, Mi J, Zeng H, Le V, Aldahl J, Hiroto A, Wu X, Sun Z, Androgen action in cell fate and communication during prostate development at single-cell resolution. Development. 2021 Jan 11;148(1):dev196048
1	J:134270 Lee JH, Kim TS, Yang TH, Koo BK, Oh SP, Lee KP, Oh HJ, Lee SH, Kong YY, Kim JM, Lim DS, A crucial role of WW45 in developing epithelial tissues in the mouse. EMBO J. 2008 Apr 23;27(8):1231-42
1	J:158528 Lee R, Chang SY, Trinh H, Tu Y, White AC, Davies BS, Bergo MO, Fong LG, Lowry WE, Young SG, Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. Hum Mol Genet. 2010 Apr 15;19(8):1603-17
1	J:316189 Lin C, Hindes A, Burns CJ, Koppel AC, Kiss A, Yin Y, Ma L, Blumenberg M, Khnykin D, Jahnsen FL, Crosby SD, Ramanan N, Efimova T, Serum response factor controls transcriptional network regulating epidermal function and hair follicle morphogenesis. J Invest Dermatol. 2013 Mar;133(3):608-617
1	J:291487 Liu D, Kousa AI, O'Neill KE, Rouse P, Popis M, Farley AM, Tomlinson SR, Ulyanchenko S, Guillemot F, Seymour PA, Jorgensen MC, Serup P, Koch U, Radtke F, Blackburn CC, Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development. Development. 2020 Jun 22;147(12):dev178582
1*	J:316269 Mehta V, Schmitz CT, Keil KP, Joshi PS, Abler LL, Lin TM, Taketo MM, Sun X, Vezina CM, Beta-catenin (CTNNB1) induces Bmp expression in urogenital sinus epithelium and participates in prostatic bud initiation and patterning. Dev Biol. 2013 Apr 15;376(2):125-35
1	J:94921 Mirosevich J, Gao N, Matusik RJ, Expression of Foxa transcription factors in the developing and adult murine prostate. Prostate. 2005 Mar 1;62(4):339-352
1	J:226707 Mizoguchi S, Suzuki K, Zhang J, Yamanaka O, Liu CY, Okada Y, Miyajima M, Kokado M, Kao WW, Yamada G, Saika S, Disruption of eyelid and cornea morphogenesis by epithelial beta-catenin gain-of-function. Mol Vis. 2015;21:793-803
1	J:173538 Packard A, Schnittke N, Romano RA, Sinha S, Schwob JE, {Delta}Np63 regulates stem cell dynamics in the Mammalian olfactory epithelium. J Neurosci. 2011 Jun 15;31(24):8748-59
1	J:240059 Park KC, Lee M, Jeon Y, Jeon R, Baek SH, Lee H, Kim KI, Skin-Specific Deletion of Mis18alpha Impedes Proliferation and Stratification of Epidermal Keratinocytes. J Invest Dermatol. 2017 Feb;137(2):414-421
1*	J:85732 Petiot A, Conti FJ, Grose R, Revest JM, Hodivala-Dilke KM, Dickson C, A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning. Development. 2003 Nov;130(22):5493-501
1	J:266746 Rudkouskaya A, Welch I, Dagnino L, ILK modulates epithelial polarity and matrix formation in hair follicles. Mol Biol Cell. 2014 Mar;25(5):620-32
1	J:341642 Schwartz B, Levi H, Menon G, Maria R, Upcher A, Kotlovski Y, Oss-Ronen L, Cohen I, ZNF750 Regulates Skin Barrier Function by Driving Cornified Envelope and Lipid Processing Pathways. J Invest Dermatol. 2023 Sep 3;
1	J:265031 Sequeira I, Neves JF, Carrero D, Peng Q, Palasz N, Liakath-Ali K, Lord GM, Morgan PR, Lombardi G, Watt FM, Immunomodulatory role of Keratin 76 in oral and gastric cancer. Nat Commun. 2018 Aug 24;9(1):3437
1	J:237499 Sima J, Piao Y, Chen Y, Schlessinger D, Molecular dynamics of Dkk4 modulates Wnt action and regulates meibomian gland development. Development. 2016 Dec 15;143(24):4723-4735
1	J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178
1	J:215310 Sun W, Wilhelmina Aalders T, Oosterwijk E, Identification of potential bladder progenitor cells in the trigone. Dev Biol. 2014 Sep 1;393(1):84-92
1*	J:108338 Tanifuji-Terai N, Terai K, Hayashi Y, Chikama T, Kao WW, Expression of keratin 12 and maturation of corneal epithelium during development and postnatal growth. Invest Ophthalmol Vis Sci. 2006 Feb;47(2):545-51
1	J:196491 Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR, Aurora kinase-A deficiency during skin development impairs cell division and stratification. J Invest Dermatol. 2013 Jan;133(1):78-86
1*	J:117802 Troy TC, Li Y, O'malley L, Turksen K, The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice. Gene Expr Patterns. 2007 Feb;7(4):423-30
1	J:59036 van der Neut R, Cachaco AS, Thorsteinsdottir S, Janssen H, Prins D, Bulthuis J, van der Valk M, Calafat J, Sonnenberg A, Partial rescue of epithelial phenotype in integrin beta4 null mice by a keratin-5 promoter driven human integrin beta4 transgene. J Cell Sci. 1999 Nov;112(Pt 22):3911-22
1	J:215769 Wang DH, Tiwari A, Kim ME, Clemons NJ, Regmi NL, Hodges WA, Berman DM, Montgomery EA, Watkins DN, Zhang X, Zhang Q, Jie C, Spechler SJ, Souza RF, Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia. J Clin Invest. 2014 Sep 2;124(9):3767-80
1*	J:329314 Wang Y, Yao B, Duan X, Li J, Song W, Enhejirigala, Li Z, Yuan X, Kong Y, Zhang Y, Fu X, Huang S, Notch1 down-regulation in lineage-restricted niches is involved in the development of mouse eccrine sweat glands. J Mol Histol. 2022 Oct;53(5):857-867
1*	J:145849 Wu X, Ferrara C, Shapiro E, Grishina I, Bmp7 expression and null phenotype in the urogenital system suggest a role in re-organization of the urethral epithelium. Gene Expr Patterns. 2009 Apr;9(4):224-30
1	J:169856 Xin Y, Lu Q, Li Q, IKK1 Control of Epidermal Differentiation Is Modulated by Notch Signaling. Am J Pathol. 2011 Apr;178(4):1568-77
1	J:330323 Yamaguchi H, Shen J, Little DR, Li M, Sozen S, Suzuki K, Mishina Y, Komatsu Y, Enhanced BMP signaling through ALK2 attenuates keratinocyte differentiation. Biochem Biophys Res Commun. 2022 Nov 12;629:101-105
1	J:100612 Yu WY, Slack JM, Tosh D, Conversion of columnar to stratified squamous epithelium in the developing mouse oesophagus. Dev Biol. 2005 Aug 1;284(1):157-70
1	J:103004 Zhang H, Hara M, Seki K, Fukuda K, Nishida T, Eyelid fusion and epithelial differentiation at the ocular surface during mouse embryonic development. Jpn J Ophthalmol. 2005 May-Jun;49(3):195-204
1	J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93
1*	J:293298 Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, Yan Y, Huang M, Tang H, Deng Y, Huang S, Zhou Z, Zhang L, Zhang L, Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development. Theranostics. 2019;9(17):5065-5084
1	J:136961 Zhang Y, Andl T, Yang SH, Teta M, Liu F, Seykora JT, Tobias JW, Piccolo S, Schmidt-Ullrich R, Nagy A, Taketo MM, Dlugosz AA, Millar SE, Activation of {beta}-catenin signaling programs embryonic epidermis to hair follicle fate. Development. 2008 Jun;135(12):2161-72