Gene Expression Literature Summary
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Assay
Age
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Western blot
14.5 DPC
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| Pkd1 polycystin 1, transient receptor potential channel interacting (Synonyms: PC1, PC-1, polycystin-1) | |
| Results | Reference |
| 1 | J:317220 Cebotaru V, Cebotaru L, Kim H, Chiaravalli M, Boletta A, Qian F, Guggino WB, Polycystin-1 negatively regulates Polycystin-2 expression via the aggresome/autophagosome pathway. J Biol Chem. 2014 Mar 7;289(10):6404-6414 |
| 1 | J:165114 Garcia-Gonzalez MA, Outeda P, Zhou Q, Zhou F, Menezes LF, Qian F, Huso DL, Germino GG, Piontek KB, Watnick T, Pkd1 and Pkd2 are required for normal placental development. PLoS One. 2010;5(9) |
| 1* | J:40260 Geng L, Segal Y, Pavlova A, Barros EJ, Lohning C, Lu W, Nigam SK , Frischauf AM , Reeders ST , Zhou J, Distribution and developmentally regulated expression of murine polycystin. Am J Physiol. 1997 Apr;272(4 Pt 2):F451-9 |
| 1 | J:224268 Kurbegovic A, Kim H, Xu H, Yu S, Cruanes J, Maser RL, Boletta A, Trudel M, Qian F, Novel functional complexity of polycystin-1 by GPS cleavage in vivo: role in polycystic kidney disease. Mol Cell Biol. 2014 Sep;34(17):3341-53 |
| 1 | J:153606 Wodarczyk C, Rowe I, Chiaravalli M, Pema M, Qian F, Boletta A, A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus. PLoS One. 2009;4(9):e7137 |
| 1 | J:127628 Yu S, Hackmann K, Gao J, He X, Piontek K, Garcia Gonzalez MA, Menezes LF, Xu H, Germino GG, Zuo J, Qian F, Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18688-93 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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