Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Fgfr1  fibroblast growth factor receptor 1   (Synonyms: Eask, Fgfr-1, FGFR-I, Flt-2, Fr1, Hspy)
Results	Reference
1*	J:92174 Aberg T, Wang XP, Kim JH, Yamashiro T, Bei M, Rice R, Ryoo HM, Thesleff I, Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis. Dev Biol. 2004 Jun 1;270(1):76-93
1	J:121107 Abraira VE, Hyun N, Tucker AF, Coling DE, Brown MC, Lu C, Hoffman GR, Goodrich LV, Changes in Sef levels influence auditory brainstem development and function. J Neurosci. 2007 Apr 18;27(16):4273-82
1	J:91667 Antonopoulou I, Mavrogiannis LA, Wilkie AO, Morriss-Kay GM, Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation. J Anat. 2004 Jun;204(6):487-99
1	J:160580 Borello U, Cobos I, Long JE, McWhirter JR, Murre C, Rubenstein JL, FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development. Neural Dev. 2008;3:17
1	J:183485 Chen D, Jarrell A, Guo C, Lang R, Atit R, Dermal beta-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation. Development. 2012 Apr;139(8):1522-33
1	J:206582 Ching ST, Cunha GR, Baskin LS, Basson MA, Klein OD, Coordinated activity of Spry1 and Spry2 is required for normal development of the external genitalia. Dev Biol. 2014 Feb 1;386(1):1-11
1	J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767
1	J:309721 Garaffo G, Provero P, Molineris I, Pinciroli P, Peano C, Battaglia C, Tomaiuolo D, Etzion T, Gothilf Y, Santoro M, Merlo GR, Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome. Front Endocrinol (Lausanne). 2013;4:203
1	J:204192 Hadjab S, Franck MC, Wang Y, Sterzenbach U, Sharma A, Ernfors P, Lallemend F, A local source of FGF initiates development of the unmyelinated lineage of sensory neurons. J Neurosci. 2013 Nov 6;33(45):17656-66
1	J:315113 Hafner R, Bohnenpoll T, Rudat C, Schultheiss TM, Kispert A, Fgfr2 is required for the expansion of the early adrenocortical primordium. Mol Cell Endocrinol. 2015 Sep 15;413:168-77
1	J:93900 Hasegawa H, Ashigaki S, Takamatsu M, Suzuki-Migishima R, Ohbayashi N, Itoh N, Takada S, Tanabe Y, Laminar patterning in the developing neocortex by temporally coordinated fibroblast growth factor signaling. J Neurosci. 2004 Oct 6;24(40):8711-9
1*	J:156926 Hayashi T, Ray CA, Younkins C, Bermingham-McDonogh O, Expression patterns of FGF receptors in the developing mammalian cochlea. Dev Dyn. 2010 Feb 3;239(3):1019-1026
1	J:343558 Ito A, Miller C, Imamura F, Suppression of BMP signaling restores mitral cell development impaired by FGF signaling deficits in mouse olfactory bulb. Mol Cell Neurosci. 2023 Dec 5;128:103913
1*	J:61352 Johnson D, Iseki S, Wilkie AO, Morriss-Kay GM, Expression patterns of Twist and Fgfr1, -2 and -3 in the developing mouse coronal suture suggest a key role for twist in suture initiation and biogenesis. Mech Dev. 2000 Mar 1;91(1-2):341-5
1	J:48564 Kettunen P, Karavanova I, Thesleff I, Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9. Dev Genet. 1998;22(4):374-85
1	J:119280 Klein OD, Minowada G, Peterkova R, Kangas A, Yu BD, Lesot H, Peterka M, Jernvall J, Martin GR, Sprouty genes control diastema tooth development via bidirectional antagonism of epithelial-mesenchymal FGF signaling. Dev Cell. 2006 Aug;11(2):181-90
1	J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60
1	J:233640 Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M, BCL11B regulates sutural patency in the mouse craniofacial skeleton. Dev Biol. 2016 Jul 15;415(2):251-60
1*	J:132412 Lee JM, Kim JY, Cho KW, Lee MJ, Cho SW, Kwak S, Cai J, Jung HS, Wnt11/Fgfr1b cross-talk modulates the fate of cells in palate development. Dev Biol. 2008 Feb 15;314(2):341-50
1	J:156171 Manuel M, Martynoga B, Yu T, West JD, Mason JO, Price DJ, The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice. Development. 2010 Feb;137(3):487-97
1	J:152616 McClellan KA, Vanderluit JL, Julian LM, Andrusiak MG, Dugal-Tessier D, Park DS, Slack RS, The p107/E2F pathway regulates fibroblast growth factor 2 responsiveness in neural precursor cells. Mol Cell Biol. 2009 Sep;29(17):4701-13
1	J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124
1*	J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
1*	J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109
1	J:75880 Ohbayashi N, Shibayama M, Kurotaki Y, Imanishi M, Fujimori T, Itoh N, Takada S, FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 2002 Apr 1;16(7):870-9
1*	J:1618 Orr-Urtreger A, Givol D, Yayon A, Yarden Y, Lonai P, Developmental expression of two murine fibroblast growth factor receptors, flg and bek. Development. 1991 Dec;113(4):1419-34
1	J:336513 Patzek S, Liu Z, de la O S, Chang S, Byrnes LE, Zhang X, Ornitz DM, Sneddon JB, Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia. iScience. 2023 Apr 21;26(4):106500
1*	J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8
1*	J:149737 Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ, The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511
1*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1	J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:300975 Weiss AC, Rivera-Reyes R, Englert C, Kispert A, Expansion of the renal capsular stroma, ureteric bud branching defects and cryptorchidism in mice with Wilms tumor 1 gene deletion in the stromal compartment of the developing kidney. J Pathol. 2020 Nov;252(3):290-303
1	J:277430 Yang LM, Cheah KSE, Huh SH, Ornitz DM, Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner. PLoS Genet. 2019 Jul;15(7):e1008254
1*	J:101025 Yaylaoglu MB, Titmus A, Visel A, Alvarez-Bolado G, Thaller C, Eichele G, Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform. Dev Dyn. 2005 Oct;234(2):371-86
1	J:226187 Yu K, Karuppaiah K, Ornitz DM, Mesenchymal fibroblast growth factor receptor signaling regulates palatal shelf elevation during secondary palate formation. Dev Dyn. 2015 Nov;244(11):1427-38