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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
14.5 DPC

8 matching records from 8 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Foxc1  forkhead box C1   (Synonyms: fkh1, fkh-1, Fkh1, FREAC3, frkhda, Mf1, Mf4)
Results  Reference
1J:273024 DiNuoscio G, Atit RP, Wnt/beta-catenin signaling in the mouse embryonic cranial mesenchyme is required to sustain the emerging differentiated meningeal layers. Genesis. 2019 Jan;57(1):e23279
1J:297206 Lee YH, Lee HT, Chen CL, Chang CH, Hsu CY, Shyu WC, Role of FOXC1 in regulating APSCs self-renewal via STI-1/PrP(C) signaling. Theranostics. 2019;9(22):6443-6465
1J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381
1J:237944 Mishra S, Choe Y, Pleasure SJ, Siegenthaler JA, Cerebrovascular defects in Foxc1 mutants correlate with aberrant WNT and VEGF-A pathways downstream of retinoic acid from the meninges. Dev Biol. 2016 Dec 01;420(1):148-165
1J:157301 Siegenthaler JA, Ashique AM, Zarbalis K, Patterson KP, Hecht JH, Kane MA, Folias AE, Choe Y, May SR, Kume T, Napoli JL, Peterson AS, Pleasure SJ, Retinoic acid from the meninges regulates cortical neuron generation. Cell. 2009 Oct 30;139(3):597-609
1J:199438 Siegenthaler JA, Choe Y, Patterson KP, Hsieh I, Li D, Jaminet SC, Daneman R, Kume T, Huang EJ, Pleasure SJ, Foxc1 is required by pericytes during fetal brain angiogenesis. Biol Open. 2013 Jul 15;2(7):647-59
1*J:166528 Zacharias AL, Gage PJ, Canonical Wnt/beta-catenin signaling is required for maintenance but not activation of Pitx2 expression in neural crest during eye development. Dev Dyn. 2010 Dec;239(12):3215-25
1J:136459 Zarbalis K, Siegenthaler JA, Choe Y, May SR, Peterson AS, Pleasure SJ, Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development. Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):14002-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory