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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
14.5 DPC

12 matching records from 12 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cxcr4  C-X-C motif chemokine receptor 4   (Synonyms: b2b220Clo, CD184, Cmkar4, fusin, PB-CKR, Sdf1r)
Results  Reference
1J:226478 Abe P, Molnar Z, Tzeng YS, Lai DM, Arnold SJ, Stumm R, Intermediate Progenitors Facilitate Intracortical Progression of Thalamocortical Axons and Interneurons through CXCL12 Chemokine Signaling. J Neurosci. 2015 Sep 23;35(38):13053-63
1*J:213419 Abe P, Mueller W, Schutz D, MacKay F, Thelen M, Zhang P, Stumm R, CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons. Development. 2014 May;141(9):1857-63
1J:108714 Holt JE, Jackson A, Roman SD, Aitken RJ, Koopman P, McLaughlin EA, CXCR4/SDF1 interaction inhibits the primordial to primary follicle transition in the neonatal mouse ovary. Dev Biol. 2006 May 15;293(2):449-60
1J:239364 Ivins S, Chappell J, Vernay B, Suntharalingham J, Martineau A, Mohun TJ, Scambler PJ, The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development. Dev Cell. 2015 May 26;33(4):455-68
1J:204198 Memi F, Abe P, Cariboni A, MacKay F, Parnavelas JG, Stumm R, CXC chemokine receptor 7 (CXCR7) affects the migration of GnRH neurons by regulating CXCL12 availability. J Neurosci. 2013 Oct 30;33(44):17527-37
1J:275071 Mimura-Yamamoto Y, Shinohara H, Kashiwagi T, Sato T, Shioda S, Seki T, Dynamics and function of CXCR4 in formation of the granule cell layer during hippocampal development. Sci Rep. 2017 Jul 17;7(1):5647
1J:310651 Ridge LA, Kewbank D, Schutz D, Stumm R, Scambler PJ, Ivins S, Dual role for CXCL12 signaling in semilunar valve development. Cell Rep. 2021 Aug 24;36(8):109610
1J:275611 Saaber F, Schutz D, Miess E, Abe P, Desikan S, Ashok Kumar P, Balk S, Huang K, Beaulieu JM, Schulz S, Stumm R, ACKR3 Regulation of Neuronal Migration Requires ACKR3 Phosphorylation, but Not beta-Arrestin. Cell Rep. 2019 Feb 5;26(6):1473-1488.e9
1J:215784 Sennett R, Rezza A, Dauber KL, Clavel C, Rendl M, Cxcr4 is transiently expressed in both epithelial and mesenchymal compartments of nascent hair follicles but is not required for follicle formation. Exp Dermatol. 2014 Oct;23(10):748-50
1J:204963 Yang S, Edman LC, Sanchez-Alcaniz JA, Fritz N, Bonilla S, Hecht J, Uhlen P, Pleasure SJ, Villaescusa JC, Marin O, Arenas E, Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons. Development. 2013 Nov;140(22):4554-64
1J:294199 Zhu Y, Hirata T, Mackay F, Murakami F, Chemokine receptor CXCR7 non-cell-autonomously controls pontine neuronal migration and nucleus formation. Sci Rep. 2020 Jul 16;10(1):11830
1J:149543 Zhu Y, Matsumoto T, Mikami S, Nagasawa T, Murakami F, SDF1/CXCR4 signalling regulates two distinct processes of precerebellar neuronal migration and its depletion leads to abnormal pontine nuclei formation. Development. 2009 Jun;136(11):1919-28

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory