Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sox2  SRY (sex determining region Y)-box 2   (Synonyms: lcc, Sox-2, ysb)
Results	Reference
1	J:251150 Aoki H, Ogino H, Tomita H, Hara A, Kunisada T, Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells. PLoS One. 2016;11(9):e0163042
1	J:216617 Benito-Gonzalez A, Doetzlhofer A, Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling. J Neurosci. 2014 Sep 17;34(38):12865-76
1	J:303700 Cajigas I, Chakraborty A, Lynam M, Swyter KR, Bastidas M, Collens L, Luo H, Ay F, Kohtz JD, Sox2-Evf2 lncRNA-mediated mechanisms of chromosome topological control in developing forebrain. Development. 2021 Mar 15;148(6):dev197202
1	J:342647 Chakraborty S, Kopitchinski N, Zuo Z, Eraso A, Awasthi P, Chari R, Mitra A, Tobias IC, Moorthy SD, Dale RK, Mitchell JA, Petros TJ, Rocha PP, Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness. Nat Genet. 2023 Feb;55(2):280-290
1	J:172213 Gill ME, Hu YC, Lin Y, Page DC, Licensing of gametogenesis, dependent on RNA binding protein DAZL, as a gateway to sexual differentiation of fetal germ cells. Proc Natl Acad Sci U S A. 2011 May 3;108(18):7443-8
1*	J:331688 Hashimoto M, Takeichi K, Murata K, Kozakai A, Yagi A, Ishikawa K, Suzuki-Nakagawa C, Kasuya Y, Fukamizu A, Nakagawa T, Regulation of neural stem cell proliferation and survival by protein arginine methyltransferase 1. Front Neurosci. 2022;16:948517
1*	J:119300 Jiao Z, Zhang ZG, Hornyak TJ, Hozeska A, Zhang RL, Wang Y, Wang L, Roberts C, Strickland FM, Chopp M, Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation. Dev Biol. 2006 Aug 15;296(2):396-408
1	J:172044 Katayama K, Melendez J, Baumann JM, Leslie JR, Chauhan BK, Nemkul N, Lang RA, Kuan CY, Zheng Y, Yoshida Y, Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation. Proc Natl Acad Sci U S A. 2011 May 3;108(18):7607-12
1	J:191198 Kopecky BJ, Jahan I, Fritzsch B, Correct Timing of Proliferation and Differentiation is Necessary for Normal Inner Ear Development and Auditory Hair Cell Viability. Dev Dyn. 2013 Feb;242(2):132-47
1*	J:308476 Le Rolle M, Massa F, Siggers P, Turchi L, Loubat A, Koo BK, Clevers H, Greenfield A, Schedl A, Chaboissier MC, Chassot AA, Arrest of WNT/beta-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2023376118
1	J:175097 Lee SH, Jeyapalan JN, Appleby V, Mohamed Noor DA, Sottile V, Scotting PJ, Dynamic methylation and expression of Oct4 in early neural stem cells. J Anat. 2010 Sep;217(3):203-13
1	J:339532 Li J, Sun L, Peng XL, Yu XM, Qi SJ, Lu ZJ, Han JJ, Shen Q, Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons. PLoS Genet. 2021 Mar;17(3):e1009355
1	J:288268 Miwa T, Ohta K, Ito N, Hattori S, Miyakawa T, Takeo T, Nakagata N, Song WJ, Minoda R, Tsukushi is essential for the development of the inner ear. Mol Brain. 2020 Mar 3;13(1):29
1	J:214809 Moniot B, Ujjan S, Champagne J, Hirai H, Aritake K, Nagata K, Dubois E, Nidelet S, Nakamura M, Urade Y, Poulat F, Boizet-Bonhoure B, Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis. Development. 2014 Sep;141(18):3561-71
1	J:261627 Mori K, Nakamura H, Kurooka H, Miyachi H, Tamada K, Sugai M, Takumi T, Yokota Y, Id2 determines intestinal identity through repression of the foregut transcription factor, Irx5. Mol Cell Biol. 2018 Feb 20;
1	J:188114 Munnamalai V, Hayashi T, Bermingham-McDonogh O, Notch prosensory effects in the Mammalian cochlea are partially mediated by fgf20. J Neurosci. 2012 Sep 12;32(37):12876-84
1	J:229930 Nechiporuk T, McGann J, Mullendorff K, Hsieh J, Wurst W, Floss T, Mandel G, The REST remodeling complex protects genomic integrity during embryonic neurogenesis. Elife. 2016;5:e09584
1	J:178908 Okano T, Xuan S, Kelley MW, Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea. J Neurosci. 2011 Dec 7;31(49):18104-18
1	J:148018 Sagai T, Amano T, Tamura M, Mizushina Y, Sumiyama K, Shiroishi T, A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings. Development. 2009 May;136(10):1665-74
1	J:145841 Tanaka S, Kamachi Y, Tanouchi A, Hamada H, Jing N, Kondoh H, Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells. Mol Cell Biol. 2004 Oct;24(20):8834-46
1	J:277545 Wang Y, Li Q, Liu C, Han F, Chen M, Zhang L, Cui X, Qin Y, Bao S, Gao F, Protein arginine methyltransferase 5 (Prmt5) is required for germ cell survival during mouse embryonic development. Biol Reprod. 2015 Apr;92(4):104
1	J:235702 Wang Y, Wu Q, Yang P, Wang C, Liu J, Ding W, Liu W, Bai Y, Yang Y, Wang H, Gao S, Wang X, LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain. Nat Commun. 2016;7:10481
1*	J:104307 Wilson ME, Yang KY, Kalousova A, Lau J, Kosaka Y, Lynn FC, Wang J, Mrejen C, Episkopou V, Clevers HC, German MS, The HMG Box Transcription Factor Sox4 Contributes to the Development of the Endocrine Pancreas. Diabetes. 2005 Dec;54(12):3402-9
1	J:223223 Wu Q, Fukuda K, Weinstein M, Graff JM, Saga Y, SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice. Development. 2015 Feb 1;142(3):575-86
1	J:317033 Xie C, Abrams SR, Herranz-Perez V, Garcia-Verdugo JM, Reiter JF, Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity. Dev Cell. 2021 Dec 20;56(24):3334-3348.e6
1	J:323100 Xu J, Xu L, Sui P, Chen J, Moya EA, Hume P, Janssen WJ, Duran JM, Thistlethwaite P, Carlin A, Gulleman P, Banaschewski B, Goldy MK, Yuan JX, Malhotra A, Pryhuber G, Crotty-Alexander L, Deutsch G, Young LR, Sun X, Excess neuropeptides in lung signal through endothelial cells to impair gas exchange. Dev Cell. 2022 Apr 11;57(7):839-853.e6
1*	J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37
1*	J:187393 Zhang L, Yuan G, Liu H, Lin H, Wan C, Chen Z, Expression pattern of Sox2 during mouse tooth development. Gene Expr Patterns. 2012 Aug;12(7-8):273-81
1*	J:240405 Zhao L, Arsenault M, Ng ET, Longmuss E, Chau TC, Hartwig S, Koopman P, SOX4 regulates gonad morphogenesis and promotes male germ cell differentiation in mice. Dev Biol. 2017 Mar 01;423(1):46-56