Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cyp11a1  cytochrome P450, family 11, subfamily a, polypeptide 1   (Synonyms: cholesterol side chain cleavage, cscc, Cyp11a, D9Ertd411e, P450scc, Scc)
Results	Reference
1*	J:93500 Bouma GJ, Hart GT, Washburn LL, Recknagel AK, Eicher EM, Using real time RT-PCR analysis to determine multiple gene expression patterns during XX and XY mouse fetal gonad development. Gene Expr Patterns. 2004 Nov;5(1):141-9
1*	J:271281 Bowles J, Feng CW, Ineson J, Miles K, Spiller CM, Harley VR, Sinclair AH, Koopman P, Retinoic Acid Antagonizes Testis Development in Mice. Cell Rep. 2018 Jul 31;24(5):1330-1341
1	J:185786 Chawengsaksophak K, Svingen T, Ng ET, Epp T, Spiller CM, Clark C, Cooper H, Koopman P, Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice. Biol Reprod. 2012 Jan;86(1):1-12
1	J:204550 Fujimoto Y, Tanaka SS, Yamaguchi YL, Kobayashi H, Kuroki S, Tachibana M, Shinomura M, Kanai Y, Morohashi K, Kawakami K, Nishinakamura R, Homeoproteins Six1 and Six4 regulate male sex determination and mouse gonadal development. Dev Cell. 2013 Aug 26;26(4):416-30
1	J:303384 Ikeda Y, Tagami A, Maekawa M, Nagai A, The conditional deletion of steroidogenic factor 1 (Nr5a1) in Sox9-Cre mice compromises testis differentiation. Sci Rep. 2021 Feb 24;11(1):4486
1	J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810
1	J:334329 Ogawa Y, Terao M, Tsuji-Hosokawa A, Tsuchiya I, Hasegawa M, Takada S, SOX9 and SRY binding sites on mouse mXYSRa/Enh13 enhancer redundantly regulate Sox9 expression to varying degrees. Hum Mol Genet. 2023 Jan 1;32(1):55-64
1	J:222045 Padua MB, Jiang T, Morse DA, Fox SC, Hatch HM, Tevosian SG, Combined loss of the GATA4 and GATA6 transcription factors in male mice disrupts testicular development and confers adrenal-like function in the testes. Endocrinology. 2015 May;156(5):1873-86
1	J:143587 Tang H, Brennan J, Karl J, Hamada Y, Raetzman L, Capel B, Notch signaling maintains Leydig progenitor cells in the mouse testis. Development. 2008 Nov;135(22):3745-53
1*	J:216502 Wainwright EN, Svingen T, Ng ET, Wicking C, Koopman P, Primary cilia function regulates the length of the embryonic trunk axis and urogenital field in mice. Dev Biol. 2014 Nov 15;395(2):342-54
1*	J:333014 Wartenberg P, Farkas I, Csillag V, Colledge WH, Hrabovszky E, Boehm U, Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain. J Neurosci. 2021 Nov 3;41(44):9177-9191
1	J:340792 Whiley PAF, Luu MCM, O'Donnell L, Handelsman DJ, Loveland KL, Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure. Front Endocrinol (Lausanne). 2023;14:1234712
1	J:292644 Whiley PAF, O'Donnell L, Moody SC, Handelsman DJ, Young JC, Richards EA, Almstrup K, Western PS, Loveland KL, Activin A Determines Steroid Levels and Composition in the Fetal Testis. Endocrinology. 2020 Jul 1;161(7)
1*	J:240405 Zhao L, Arsenault M, Ng ET, Longmuss E, Chau TC, Hartwig S, Koopman P, SOX4 regulates gonad morphogenesis and promotes male germ cell differentiation in mice. Dev Biol. 2017 Mar 01;423(1):46-56
1*	J:220472 Zhao L, Svingen T, Ng ET, Koopman P, Female-to-male sex reversal in mice caused by transgenic overexpression of Dmrt1. Development. 2015 Mar 15;142(6):1083-8
1	J:338076 Zhao L, Thomson E, Ng ET, Longmuss E, Svingen T, Bagheri-Fam S, Quinn A, Harley VR, Harrison LC, Pelosi E, Koopman P, Functional Analysis of Mmd2 and Related PAQR Genes During Sex Determination in Mice. Sex Dev. 2022;16(4):270-282