Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Fgf9  fibroblast growth factor 9   (Synonyms: Eks, glia activating factor)
Results	Reference
1*	J:187602 Al Alam D, Sala FG, Baptista S, Galzote R, Danopoulos S, Tiozzo C, Gage P, Grikscheit T, Warburton D, Frey MR, Bellusci S, FGF9-Pitx2-FGF10 signaling controls cecal formation in mice. Dev Biol. 2012 Sep 15;369(2):340-8
1	J:185582 Barak H, Huh SH, Chen S, Jeanpierre C, Martinovic J, Parisot M, Bole-Feysot C, Nitschke P, Salomon R, Antignac C, Ornitz DM, Kopan R, FGF9 and FGF20 Maintain the Stemness of Nephron Progenitors in Mice and Man. Dev Cell. 2012 Jun 12;22(6):1191-207
1*	J:93500 Bouma GJ, Hart GT, Washburn LL, Recknagel AK, Eicher EM, Using real time RT-PCR analysis to determine multiple gene expression patterns during XX and XY mouse fetal gonad development. Gene Expr Patterns. 2004 Nov;5(1):141-9
1*	J:164280 Bowles J, Feng CW, Spiller C, Davidson TL, Jackson A, Koopman P, FGF9 suppresses meiosis and promotes male germ cell fate in mice. Dev Cell. 2010 Sep 14;19(3):440-9
1*	J:167039 Brade T, Kumar S, Cunningham TJ, Chatzi C, Zhao X, Cavallero S, Li P, Sucov HM, Ruiz-Lozano P, Duester G, Retinoic acid stimulates myocardial expansion by induction of hepatic erythropoietin which activates epicardial Igf2. Development. 2011 Jan;138(1):139-48
1	J:176242 Charles C, Hovorakova M, Ahn Y, Lyons DB, Marangoni P, Churava S, Biehs B, Jheon A, Lesot H, Balooch G, Krumlauf R, Viriot L, Peterkova R, Klein OD, Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. Development. 2011 Sep;138(18):4063-73
1	J:179634 Chassot AA, Gregoire EP, Lavery R, Taketo MM, de Rooij DG, Adams IR, Chaboissier MC, RSPO1/beta-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary. PLoS One. 2011;6(10):e25641
1	J:133933 Chassot AA, Ranc F, Gregoire EP, Roepers-Gajadien HL, Taketo MM, Camerino G, de Rooij DG, Schedl A, Chaboissier MC, Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary. Hum Mol Genet. 2008 May 1;17(9):1264-77
1	J:339854 Chen SY, Liu FC, The Fgf9-Nolz1-Wnt2 axis regulates morphogenesis of the lung. Development. 2023 Aug 15;150(16):dev201827
1	J:129651 Chi L, Itaranta P, Zhang S, Vainio S, Sprouty2 is involved in male sex organogenesis by controlling fibroblast growth factor 9-induced mesonephric cell migration to the developing testis. Endocrinology. 2006 Aug;147(8):3777-88
1*	J:177793 Combes AN, Bowles J, Feng CW, Chiu HS, Khoo PL, Jackson A, Little MH, Tam PP, Koopman P, Expression and functional analysis of Dkk1 during early gonadal development. Sex Dev. 2011;5(3):124-30
1	J:158334 Combes AN, Spiller CM, Harley VR, Sinclair AH, Dunwoodie SL, Wilhelm D, Koopman P, Gonadal defects in Cited2-mutant mice indicate a role for SF1 in both testis and ovary differentiation. Int J Dev Biol. 2010;54(4):683-9
1	J:199496 Cornett B, Snowball J, Varisco BM, Lang R, Whitsett J, Sinner D, Wntless is required for peripheral lung differentiation and pulmonary vascular development. Dev Biol. 2013 Jul 1;379(1):38-52
1	J:325442 Dai H, Zhu M, Li W, Si G, Xing Y, Activation of PI3K/p110alpha in the Lung Mesenchyme Affects Branching Morphogenesis and Club Cell Differentiation. Front Cell Dev Biol. 2022;10:880206
1*	J:231094 Du W, Prochazka J, Prochazkova M, Klein OD, Expression of FGFs during early mouse tongue development. Gene Expr Patterns. 2016 Mar;20(2):81-7
1	J:308828 Gilbert RM, Schappell LE, Gleghorn JP, Defective mesothelium and limited physical space are drivers of dysregulated lung development in a genetic model of congenital diaphragmatic hernia. Development. 2021 May 15;148(10):dev199460
1	J:167078 Gregoire EP, Lavery R, Chassot AA, Akiyama H, Treier M, Behringer RR, Chaboissier MC, Transient development of ovotestes in XX Sox9 transgenic mice. Dev Biol. 2011 Jan 1;349(1):65-77
1*	J:139637 Hotta Y, Sasaki S, Konishi M, Kinoshita H, Kuwahara K, Nakao K, Itoh N, Fgf16 is required for cardiomyocyte proliferation in the mouse embryonic heart. Dev Dyn. 2008 Sep 24;237(10):2947-2954
1	J:232894 Hrycaj SM, Dye BR, Baker NC, Larsen BM, Burke AC, Spence JR, Wellik DM, Hox5 Genes Regulate the Wnt2/2b-Bmp4-Signaling Axis during Lung Development. Cell Rep. 2015 Aug 11;12(6):903-12
1	J:239872 Larsen BM, Hrycaj SM, Newman M, Li Y, Wellik DM, Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation. Development. 2015 Nov 15;142(22):3859-68
1	J:316151 Lin FJ, You LR, Yu CT, Hsu WH, Tsai MJ, Tsai SY, Endocardial cushion morphogenesis and coronary vessel development require chicken ovalbumin upstream promoter-transcription factor II. Arterioscler Thromb Vasc Biol. 2012 Nov;32(11):e135-46
1	J:149544 Moniot B, Declosmenil F, Barrionuevo F, Scherer G, Aritake K, Malki S, Marzi L, Cohen-Solal A, Georg I, Klattig J, Englert C, Kim Y, Capel B, Eguchi N, Urade Y, Boizet-Bonhoure B, Poulat F, The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation. Development. 2009 Jun;136(11):1813-21
1	J:276879 Noe N, Shim A, Millette K, Luo Y, Azhar M, Shi W, Warburton D, Turcatel G, Mesenchyme-specific deletion of Tgf-beta1 in the embryonic lung disrupts branching morphogenesis and induces lung hypoplasia. Lab Invest. 2019 Apr 25;
1	J:276812 Ortega EA, Salvador Q, Fernandez M, Ward MA, Alterations of sex determination pathways in the genital ridges of males with limited Y chromosome genes. Biol Reprod. 2019 Mar 1;100(3):810-823
1	J:197599 Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S, Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet. 2013;9(1):e1003160
1*	J:209131 Saba R, Wu Q, Saga Y, CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways. Dev Biol. 2014 May 15;389(2):173-81
1	J:92065 Schmahl J, Kim Y, Colvin JS, Ornitz DM, Capel B, Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination. Development. 2004 Aug;131(15):3627-36
1	J:173650 Sgantzis N, Yiakouvaki A, Remboutsika E, Kontoyiannis DL, HuR controls lung branching morphogenesis and mesenchymal FGF networks. Dev Biol. 2011 Jun 15;354(2):267-79
1	J:119030 Spater D, Hill TP, O'sullivan RJ, Gruber M, Conner DA, Hartmann C, Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis. Development. 2006 Aug;133(15):3039-49
1	J:193313 Takase HM, Itoh T, Ino S, Wang T, Koji T, Akira S, Takikawa Y, Miyajima A, FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration. Genes Dev. 2013 Jan 15;27(2):169-81
1	J:305205 Tang F, Richardson N, Albina A, Chaboissier MC, Perea-Gomez A, Mouse Gonad Development in the Absence of the Pro-Ovary Factor WNT4 and the Pro-Testis Factor SOX9. Cells. 2020 Apr 29;9(5):1103
1	J:325558 Torres-Cano A, Portella-Fortuny R, Muller-Sanchez C, Porras-Marfil S, Ramiro-Pareta M, Chau YY, Reina M, Soriano FX, Martinez-Estrada OM, Deletion of Wt1 during early gonadogenesis leads to differences of sex development in male and female adult mice. PLoS Genet. 2022 Jun;18(6):e1010240
1	J:292644 Whiley PAF, O'Donnell L, Moody SC, Handelsman DJ, Young JC, Richards EA, Almstrup K, Western PS, Loveland KL, Activin A Determines Steroid Levels and Composition in the Fetal Testis. Endocrinology. 2020 Jul 1;161(7)
1*	J:103443 Wilhelm D, Martinson F, Bradford S, Wilson MJ, Combes AN, Beverdam A, Bowles J, Mizusaki H, Koopman P, Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. Dev Biol. 2005 Nov 1;287(1):111-24
1*	J:297585 Yang Y, Zhu X, Jia X, Hou W, Zhou G, Ma Z, Yu B, Pi Y, Zhang X, Wang J, Wang G, Phosphorylation of Msx1 promotes cell proliferation through the Fgf9/18-MAPK signaling pathway during embryonic limb development. Nucleic Acids Res. 2020 Nov 18;48(20):11452-11467
1	J:242896 Yao C, Carraro G, Konda B, Guan X, Mizuno T, Chiba N, Kostelny M, Kurkciyan A, David G, McQualter JL, Stripp BR, Sin3a regulates epithelial progenitor cell fate during lung development. Development. 2017 Jul 15;144(14):2618-2628
1	J:224791 Yin Y, Castro AM, Hoekstra M, Yan TJ, Kanakamedala AC, Dehner LP, Hill DA, Ornitz DM, Fibroblast Growth Factor 9 Regulation by MicroRNAs Controls Lung Development and Links DICER1 Loss to the Pathogenesis of Pleuropulmonary Blastoma. PLoS Genet. 2015 May;11(5):e1005242