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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
12.5 DPC

18 matching records from 18 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Sema3c  sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C   (Synonyms: 1110036B02Rik, Semae)
Results  Reference
1*J:71241 Brown CB, Feiner L, Lu MM, Li J, Ma X, Webber AL, Jia L, Raper JA, Epstein JA, PlexinA2 and semaphorin signaling during cardiac neural crest development. Development. 2001 Aug;128(16):3071-80
1J:333925 Chen T, Song S, Jiang H, Lian H, Hu S, Single Cell Sequencing Reveals Mechanisms of Persistent Truncus Arteriosus Formation after PDGFRalpha and PDGFRbeta Double Knockout in Cardiac Neural Crest Cells. Genes (Basel). 2022 Sep 23;13(10)
1*J:100439 Cohen S, Funkelstein L, Livet J, Rougon G, Henderson CE, Castellani V, Mann F, A semaphorin code defines subpopulations of spinal motor neurons during mouse development. Eur J Neurosci. 2005 Apr;21(7):1767-76
1J:282348 Dasgupta K, Chung JU, Asam K, Jeong J, Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling. Dev Biol. 2019 Nov 15;455(2):434-448
1J:174966 Erskine L, Reijntjes S, Pratt T, Denti L, Schwarz Q, Vieira JM, Alakakone B, Shewan D, Ruhrberg C, VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm. Neuron. 2011 Jun 9;70(5):951-65
1*J:71240 Feiner L, Webber AL, Brown CB, Lu MM, Jia L, Feinstein P, Mombaerts P, Epstein JA, Raper JA, Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption. Development. 2001 Aug;128(16):3061-70
1*J:182314 Lee MP, Yutzey KE, Twist1 directly regulates genes that promote cell proliferation and migration in developing heart valves. PLoS One. 2011;6(12):e29758
1J:107814 Lepore JJ, Mericko PA, Cheng L, Lu MM, Morrisey EE, Parmacek MS, GATA-6 regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis. J Clin Invest. 2006 Apr;116(4):929-39
1*J:68163 Loes S, Kettunen P, Kvinnsland IH, Taniguchi M, Fujisawa H, Luukko K, Expression of class 3 semaphorins and neuropilin receptors in the developing mouse tooth. Mech Dev. 2001 Mar;101(1-2):191-4
1*J:93141 Mattar P, Britz O, Johannes C, Nieto M, Ma L, Rebeyka A, Klenin N, Polleux F, Guillemot F, Schuurmans C, A screen for downstream effectors of Neurogenin2 in the embryonic neocortex. Dev Biol. 2004 Sep 15;273(2):373-89
1J:197897 Mi D, Carr CB, Georgala PA, Huang YT, Manuel MN, Jeanes E, Niisato E, Sansom SN, Livesey FJ, Theil T, Hasenpusch-Theil K, Simpson TI, Mason JO, Price DJ, Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb. Neuron. 2013 Apr 24;78(2):269-84
1J:225355 Plein A, Calmont A, Fantin A, Denti L, Anderson NA, Scambler PJ, Ruhrberg C, Neural crest-derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation. J Clin Invest. 2015 Jul 1;125(7):2661-76
1*J:25500 Puschel AW, Adams RH, Betz H, Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension. Neuron. 1995 May;14(5):941-8
1*J:37600 Puschel AW, Adams RH, Betz H, The sensory innervation of the mouse spinal cord may be patterned by differential expression of and differential responsiveness to semaphorins. Mol Cell Neurosci. 1996 May;7(5):419-31
1*J:156467 Saxena A, Tabin CJ, miRNA-processing enzyme Dicer is necessary for cardiac outflow tract alignment and chamber septation. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):87-91
1J:332242 Vieira JR, Shah B, Dupraz S, Paredes I, Himmels P, Schermann G, Adler H, Motta A, Gartner L, Navarro-Aragall A, Ioannou E, Dyukova E, Bonnavion R, Fischer A, Bonanomi D, Bradke F, Ruhrberg C, Ruiz de Almodovar C, Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development. Neuron. 2022 Dec 21;110(24):4074-4089.e6
1*J:308710 Vincentz JW, Firulli BA, Toolan KP, Osterwalder M, Pennacchio LA, Firulli AB, HAND transcription factors cooperatively specify the aorta and pulmonary trunk. Dev Biol. 2021 Aug;476:1-10
1*J:138310 Xu C, Fan CM, Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei. Gene Expr Patterns. 2008 Sep;8(7-8):502-7

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory