Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hes5  hes family bHLH transcription factor 5   (Synonyms: bHLHb38)
Results	Reference
1	J:226938 Bagherie-Lachidan M, Reginensi A, Pan Q, Zaveri HP, Scott DA, Blencowe BJ, Helmbacher F, McNeill H, Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool. Development. 2015 Aug 1;142(15):2564-73
1	J:76133 Brennan J, Karl J, Capel B, Divergent Vascular Mechanisms Downstream of Sry Establish the Arterial System in the XY Gonad. Dev Biol. 2002 Apr 15;244(2):418-28
1	J:264379 Cardenas A, Villalba A, de Juan Romero C, Pico E, Kyrousi C, Tzika AC, Tessier-Lavigne M, Ma L, Drukker M, Cappello S, Borrell V, Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels. Cell. 2018 Jul 26;174(3):590-606.e21
1*	J:51598 Casarosa S, Fode C, Guillemot F, Mash1 regulates neurogenesis in the ventral telencephalon. Development. 1999 Feb;126(3):525-34
1*	J:75936 Cau E, Casarosa S, Guillemot F, Mash1 and Ngn1 control distinct steps of determination and differentiation in the olfactory sensory neuron lineage. Development. 2002 Apr;129(8):1871-80
1*	J:62024 Cau E, Gradwohl G, Casarosa S, Kageyama R, Guillemot F, Hes genes regulate sequential stages of neurogenesis in the olfactory epithelium. Development. 2000 Jun;127(11):2323-32
1	J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21
1	J:175535 Deng Q, Andersson E, Hedlund E, Alekseenko Z, Coppola E, Panman L, Millonig JH, Brunet JF, Ericson J, Perlmann T, Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development. Development. 2011 Aug;138(16):3399-408
1*	J:206224 Dixit R, Tachibana N, Touahri Y, Zinyk D, Logan C, Schuurmans C, Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation. Gene Expr Patterns. 2014 Jan;14(1):42-54
1	J:285759 Esteve P, Crespo I, Kaimakis P, Sandonis A, Bovolenta P, Sfrp1 Modulates Cell-signaling Events Underlying Telencephalic Patterning, Growth and Differentiation. Cereb Cortex. 2019 Mar 1;29(3):1059-1074
1	J:172287 Esteve P, Sandonis A, Cardozo M, Malapeira J, Ibanez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P, SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis. Nat Neurosci. 2011 May;14(5):562-9
1	J:59428 Fode C, Ma Q, Casarosa S, Ang SL, Anderson DJ, Guillemot F, A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons. Genes Dev. 2000 Jan 1;14(1):67-80
1	J:155627 Genethliou N, Panayiotou E, Panayi H, Orford M, Mean R, Lapathitis G, Gill H, Raoof S, De Gasperi R, Elder G, Kessaris N, Richardson WD, Malas S, SOX1 links the function of neural patterning and Notch signalling in the ventral spinal cord during the neuron-glial fate switch. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1114-20
1	J:229100 Goto M, Hojo M, Ando M, Kita A, Kitagawa M, Ohtsuka T, Kageyama R, Miyamoto S, Hes1 and Hes5 are required for differentiation of pituicytes and formation of the neurohypophysis in pituitary development. Brain Res. 2015 Nov 2;1625:206-17
1	J:119019 Gutin G, Fernandes M, Palazzolo L, Paek H, Yu K, Ornitz DM, McConnell SK, Hebert JM, FGF signalling generates ventral telencephalic cells independently of SHH. Development. 2006 Aug;133(15):2937-46
1*	J:293446 Han S, Dennis DJ, Balakrishnan A, Dixit R, Britz O, Zinyk D, Touahri Y, Olender T, Brand M, Guillemot F, Kurrasch D, Schuurmans C, A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis. Development. 2018 Oct 1;145(19):dev157719
1*	J:62163 Handler M, Yang X, Shen J, Presenilin-1 regulates neuronal differentiation during neurogenesis. Development. 2000 Jun;127(12):2593-606
1	J:164376 Hartman BH, Reh TA, Bermingham-McDonogh O, Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear. Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15792-7
1	J:170495 Ikeda K, Kageyama R, Suzuki Y, Kawakami K, Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development. Int J Dev Biol. 2010;54(10):1453-64
1	J:139170 Imayoshi I, Shimogori T, Ohtsuka T, Kageyama R, Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development. 2008 Aug;135(15):2531-41
1*	J:144373 Kinameri E, Inoue T, Aruga J, Imayoshi I, Kageyama R, Shimogori T, Moore AW, Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS One. 2008;3(12):e3859
1*	J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735
1*	J:173286 Long JE, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
1*	J:173287 Long JE, Swan C, Liang WS, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
1	J:160654 Machold RP, Kittell DJ, Fishell GJ, Antagonism between Notch and bone morphogenetic protein receptor signaling regulates neurogenesis in the cerebellar rhombic lip. Neural Dev. 2007;2:5
1	J:101735 Mason HA, Rakowiecki SM, Raftopoulou M, Nery S, Huang Y, Gridley T, Fishell G, Notch signaling coordinates the patterning of striatal compartments. Development. 2005 Oct;132(19):4247-58
1*	J:166398 Masserdotti G, Badaloni A, Green YS, Croci L, Barili V, Bergamini G, Vetter ML, Consalez GG, ZFP423 coordinates Notch and bone morphogenetic protein signaling, selectively up-regulating Hes5 gene expression. J Biol Chem. 2010 Oct 1;285(40):30814-24
1*	J:260421 Mesman S, Kruse SJ, Smidt MP, Expression analyzes of early factors in midbrain differentiation programs. Gene Expr Patterns. 2018 Jan;27:8-15
1	J:310534 Miao N, Bian S, Lee T, Mubarak T, Huang S, Wen Z, Hussain G, Sun T, Opposite Roles of Wnt7a and Sfrp1 in Modulating Proper Development of Neural Progenitors in the Mouse Cerebral Cortex. Front Mol Neurosci. 2018;11:247
1	J:279209 Murata J, Ohtsuka T, Tokunaga A, Nishiike S, Inohara H, Okano H, Kageyama R, Notch-Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1. J Neurosci Res. 2009 Dec;87(16):3521-34
1	J:285050 Ochi S, Imaizumi Y, Shimojo H, Miyachi H, Kageyama R, Oscillatory expression of Hes1 regulates cell proliferation and neuronal differentiation in the embryonic brain. Development. 2020 Feb 26;147(4):dev182204
1	J:74525 Parras CM, Schuurmans C, Scardigli R, Kim J, Anderson DJ, Guillemot F, Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity. Genes Dev. 2002 Feb 1;16(3):324-38
1	J:188279 Peng C, Li N, Ng YK, Zhang J, Meier F, Theis FJ, Merkenschlager M, Chen W, Wurst W, Prakash N, A Unilateral Negative Feedback Loop Between miR-200 microRNAs and Sox2/E2F3 Controls Neural Progenitor Cell-Cycle Exit and Differentiation. J Neurosci. 2012 Sep 19;32(38):13292-13308
1*	J:87368 Raetzman LT, Ross SA, Cook S, Dunwoodie SL, Camper SA, Thomas PQ, Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression. Dev Biol. 2004 Jan 15;265(2):329-40
1*	J:252115 Riesenberg AN, Conley KW, Le TT, Brown NL, Separate and coincident expression of Hes1 and Hes5 in the developing mouse eye. Dev Dyn. 2018 Jan;247(1):212-221
1	J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77
1	J:149456 Rocha SF, Lopes SS, Gossler A, Henrique D, Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity. Dev Biol. 2009 Apr 1;328(1):54-65
1	J:187684 Rodriguez M, Choi J, Park S, Sockanathan S, Gde2 regulates cortical neuronal identity by controlling the timing of cortical progenitor differentiation. Development. 2012 Oct;139(20):3870-9
1*	J:310127 Ruan X, Liu G, Zhou J, Chen P, Sun C, Liu W, Wu C, Hou L, Yin B, Qiang B, Shu P, Peng X, Zbed3 Is Indispensable for Wnt Signaling Regulation of Cortical Layers Formation in Developing Brain. Cereb Cortex. 2021 Jul 29;31(9):4078-4091
1*	J:215514 Saulnier A, Keruzore M, De Clercq S, Bar I, Moers V, Magnani D, Walcher T, Filippis C, Kricha S, Parlier D, Viviani L, Matson CK, Nakagawa Y, Theil T, Gotz M, Mallamaci A, Marine JC, Zarkower D, Bellefroid EJ, The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
1	J:130594 Schwarting GA, Gridley T, Henion TR, Notch1 expression and ligand interactions in progenitor cells of the mouse olfactory epithelium. J Mol Histol. 2007 Dec;38(6):543-53
1*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1	J:227685 Shimojo H, Isomura A, Ohtsuka T, Kori H, Miyachi H, Kageyama R, Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. Genes Dev. 2016 Jan 1;30(1):102-16
1	J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4
1	J:143587 Tang H, Brennan J, Karl J, Hamada Y, Raetzman L, Capel B, Notch signaling maintains Leydig progenitor cells in the mouse testis. Development. 2008 Nov;135(22):3745-53
1	J:196218 Wang B, Long JE, Flandin P, Pla R, Waclaw RR, Campbell K, Rubenstein JL, Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants. J Comp Neurol. 2013 May 1;521(7):1561-84
1	J:147161 Wang B, Waclaw RR, Allen ZJ 2nd, Guillemot F, Campbell K, Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon. Neural Dev. 2009;4:5
1	J:109482 Wildner H, Muller T, Cho SH, Brohl D, Cepko CL, Guillemot F, Birchmeier C, dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development. Development. 2006 Jun;133(11):2105-13
1*	J:314887 Zhang M, Zhou J, Jiao L, Xu L, Hou L, Yin B, Qiang B, Lu S, Shu P, Peng X, Long Non-coding RNA T-uc.189 Modulates Neural Progenitor Cell Fate by Regulating Srsf3 During Mouse Cerebral Cortex Development. Front Neurosci. 2021;15:709684
1	J:309104 Zheng MH, Shi M, Pei Z, Gao F, Han H, Ding YQ, The transcription factor RBP-J is essential for retinal cell differentiation and lamination. Mol Brain. 2009 Dec 18;2:38
1	J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168
1*	J:136395 Zordan P, Croci L, Hawkes R, Consalez GG, Comparative analysis of proneural gene expression in the embryonic cerebellum. Dev Dyn. 2008 Jun;237(6):1726-35