Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Msx2  msh homeobox 2   (Synonyms: Hox8, Hox-8, Hox8.1)
Results	Reference
1*	J:74162 Abdelwahid E, Rice D, Pelliniemi LJ, Jokinen E, Overlapping and differential localization of Bmp-2, Bmp-4, Msx-2 and apoptosis in the endocardial cushion and adjacent tissues of the developing mouse heart. Cell Tissue Res. 2001 Jul;305(1):67-78
1	J:98096 Aberg T, Rice R, Rice D, Thesleff I, Waltimo-Siren J, Chondrogenic potential of mouse calvarial mesenchyme. J Histochem Cytochem. 2005 May;53(5):653-63
1*	J:39336 Ahuja HS, James W, Zakeri Z, Rescue of the limb deformity in hammertoe mutant mice by retinoic acid-induced cell death. Dev Dyn. 1997 Apr;208(4):466-81
1	J:326693 Angelozzi M, Pellegrino da Silva R, Gonzalez MV, Lefebvre V, Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors. Cell Rep. 2022 Jul 12;40(2):111045
1	J:91667 Antonopoulou I, Mavrogiannis LA, Wilkie AO, Morriss-Kay GM, Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation. J Anat. 2004 Jun;204(6):487-99
1	J:161903 Boogerd KJ, Wong LY, Christoffels VM, Klarenbeek M, Ruijter JM, Moorman AF, Barnett P, Msx1 and Msx2 are functional interacting partners of T-box factors in the regulation of Connexin43. Cardiovasc Res. 2008 Jun 1;78(3):485-93
1	J:232481 Caronia-Brown G, Anderegg A, Awatramani R, Expression and functional analysis of the Wnt/beta-catenin induced mir-135a-2 locus in embryonic forebrain development. Neural Dev. 2016;11:9
1	J:46989 Celli G, LaRochelle WJ, Mackem S, Sharp R, Merlino G, Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning. EMBO J. 1998 Mar 16;17(6):1642-55
1*	J:267540 Cesario JM, Landin Malt A, Chung JU, Khairallah MP, Dasgupta K, Asam K, Deacon LJ, Choi V, Almaidhan AA, Darwiche NA, Kim J, Johnson RL, Jeong J, Anti-osteogenic function of a LIM-homeodomain transcription factor LMX1B is essential to early patterning of the calvaria. Dev Biol. 2018 Nov 15;443(2):103-116
1	J:282348 Dasgupta K, Chung JU, Asam K, Jeong J, Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling. Dev Biol. 2019 Nov 15;455(2):434-448
1	J:184618 Deckelbaum RA, Holmes G, Zhao Z, Tong C, Basilico C, Loomis CA, Regulation of cranial morphogenesis and cell fate at the neural crest-mesoderm boundary by engrailed 1. Development. 2012 Apr;139(7):1346-58
1*	J:48569 Grove EA, Tole S, Limon J, Yip L, Ragsdale CW, The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice. Development. 1998 Jun;125(12):2315-25
1*	J:21617 Gunther T, Struwe M, Aguzzi A, Schughart K, Open brain, a new mouse mutant with severe neural tube defects, shows altered gene expression patterns in the developing spinal cord. Development. 1994 Nov;120(11):3119-30
1*	J:125119 Han J, Ishii M, Bringas P Jr, Maas RL, Maxson RE Jr, Chai Y, Concerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone development. Mech Dev. 2007 Sep-Oct;124(9-10):729-45
1	J:139170 Imayoshi I, Shimogori T, Ohtsuka T, Kageyama R, Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development. 2008 Aug;135(15):2531-41
1*	J:87044 Ishii M, Merrill AE, Chan YS, Gitelman I, Rice DP, Sucov HM, Maxson RE Jr, Msx2 and Twist cooperatively control the development of the neural crest-derived skeletogenic mesenchyme of the murine skull vault. Development. 2003 Dec;130(24):6131-42
1*	J:4384 Jowett AK, Vainio S, Ferguson MW, Sharpe PT, Thesleff I, Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth. Development. 1993 Feb;117(2):461-70
1	J:51084 Keranen SV, Aberg T, Kettunen P, Thesleff I, Jernvall J, Association of developmental regulatory genes with the development of different molar tooth shapes in two species of rodents. Dev Genes Evol. 1998 Nov;208(9):477-86
1	J:130228 Liu F, Chu EY, Watt B, Zhang Y, Gallant NM, Andl T, Yang SH, Lu MM, Piccolo S, Schmidt-Ullrich R, Taketo MM, Morrisey EE, Atit R, Dlugosz AA, Millar SE, Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol. 2008 Jan 1;313(1):210-24
1	J:160654 Machold RP, Kittell DJ, Fishell GJ, Antagonism between Notch and bone morphogenetic protein receptor signaling regulates neurogenesis in the cerebellar rhombic lip. Neural Dev. 2007;2:5
1*	J:11525 Monaghan AP, Davidson DR, Sime C, Graham E, Baldock R, Bhattacharya SS, Hill RE, The Msh-like homeobox genes define domains in the developing vertebrate eye. Development. 1991 Aug;112(4):1053-61
1	J:262487 Murgai A, Altmeyer S, Wiegand S, Tylzanowski P, Stricker S, Cooperation of BMP and IHH signaling in interdigital cell fate determination. PLoS One. 2018;13(5):e0197535
1	J:162170 Roybal PG, Wu NL, Sun J, Ting MC, Schafer CA, Maxson RE, Inactivation of Msx1 and Msx2 in neural crest reveals an unexpected role in suppressing heterotopic bone formation in the head. Dev Biol. 2010 Jul 1;343(1-2):28-39
1*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1	J:196596 Singh N, Gupta M, Trivedi CM, Singh MK, Li L, Epstein JA, Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression. Dev Biol. 2013 May 15;377(2):333-44
1	J:194058 Sun J, Ishii M, Ting MC, Maxson R, Foxc1 controls the growth of the murine frontal bone rudiment by direct regulation of a Bmp response threshold of Msx2. Development. 2013 Mar;140(5):1034-44
1*	J:33667 Takahashi Y, Organization of the spina bifida neural tube in Splotch (Pax-3 defective) mouse embryos. Dev Growth Differ. 1996 FEB;38(1):23-31
1	J:101189 Timmer JR, Mak TW, Manova K, Anderson KV, Niswander L, Tissue morphogenesis and vascular stability require the Frem2 protein, product of the mouse myelencephalic blebs gene. Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11746-50
1*	J:28253 Tureckova J, Sahlberg C, Aberg T, Ruch JV, Thesleff I, Peterkova R, Comparison of expression of the msx-1, msx-2, BMP-2 and BMP-4 genes in the mouse upper diastemal and molar tooth primordia. Int J Dev Biol. 1995 Jun;39(3):459-68
1	J:311534 Wan Y, Lantz B, Cusack BJ, Szabo-Rogers HL, Prickle1 regulates differentiation of frontal bone osteoblasts. Sci Rep. 2018 Dec 21;8(1):18021
1*	J:35536 Wang W, Chen X, Xu H, Lufkin T, Msx3: a novel murine homologue of the Drosophila msh homeobox gene restricted to the dorsal embryonic central nervous system. Mech Dev. 1996 Aug;58(1-2):203-15
1*	J:83306 Zhang Z, Zhang X, Avniel WA, Song Y, Jones SM, Jones TA, Fermin C, Chen Y, Malleal processus brevis is dispensable for normal hearing in mice. Dev Dyn. 2003 May;227(1):69-77
1	J:184697 Zhao J, Kawai K, Wang H, Wu D, Wang M, Yue Z, Zhang J, Liu YH, Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly. Am J Pathol. 2012 Jun;180(6):2230-9