Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Fgf8  fibroblast growth factor 8   (Synonyms: Aigf, Fgf-8)
Results	Reference
1	J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58
1	J:283343 Bastida MF, Perez-Gomez R, Trofka A, Zhu J, Rada-Iglesias A, Sheth R, Stadler HS, Mackem S, Ros MA, The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1090-1096
1	J:342014 Chen Y, Zhou T, Liao Z, Gao W, Wu J, Zhang S, Li Y, Liu H, Zhou H, Xu C, Su P, Hnrnpk is essential for embryonic limb bud development as a transcription activator and a collaborator of insulator protein Ctcf. Cell Death Differ. 2023 Oct;30(10):2293-2308
1	J:334109 Cova G, Glaser J, Schopflin R, Prada-Medina CA, Ali S, Franke M, Falcone R, Federer M, Ponzi E, Ficarella R, Novara F, Wittler L, Timmermann B, Gentile M, Zuffardi O, Spielmann M, Mundlos S, Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve split-hand/foot malformation type 3. Nat Commun. 2023 Mar 17;14(1):1475
1*	J:231094 Du W, Prochazka J, Prochazkova M, Klein OD, Expression of FGFs during early mouse tongue development. Gene Expr Patterns. 2016 Mar;20(2):81-7
1	J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457
1	J:204192 Hadjab S, Franck MC, Wang Y, Sterzenbach U, Sharma A, Ernfors P, Lallemend F, A local source of FGF initiates development of the unmyelinated lineage of sensory neurons. J Neurosci. 2013 Nov 6;33(45):17656-66
1	J:157252 Hiramatsu R, Harikae K, Tsunekawa N, Kurohmaru M, Matsuo I, Kanai Y, FGF signaling directs a center-to-pole expansion of tubulogenesis in mouse testis differentiation. Development. 2010 Jan;137(2):303-12
1	J:245137 Kawata M, Taniguchi Y, Mori D, Yano F, Ohba S, Chung UI, Shimogori T, Mills AA, Tanaka S, Saito T, Different regulation of limb development by p63 transcript variants. PLoS One. 2017;12(3):e0174122
1	J:191198 Kopecky BJ, Jahan I, Fritzsch B, Correct Timing of Proliferation and Differentiation is Necessary for Normal Inner Ear Development and Auditory Hair Cell Viability. Dev Dyn. 2013 Feb;242(2):132-47
1	J:237505 Norrie JL, Li Q, Co S, Huang BL, Ding D, Uy JC, Ji Z, Mackem S, Bedford MT, Galli A, Ji H, Vokes SA, PRMT5 is essential for the maintenance of chondrogenic progenitor cells in the limb bud. Development. 2016 Dec 15;143(24):4608-4619
1*	J:74134 Pickles JO, The expression of fibroblast growth factors and their receptors in the embryonic and neonatal mouse inner ear. Hear Res. 2001 May;155(1-2):54-62
1	J:210664 Restelli M, Lopardo T, Lo Iacono N, Garaffo G, Conte D, Rustighi A, Napoli M, Del Sal G, Perez-Morga D, Costanzo A, Merlo GR, Guerrini L, DLX5, FGF8 and the Pin1 isomerase control DeltaNp63alpha protein stability during limb development: a regulatory loop at the basis of the SHFM and EEC congenital malformations. Hum Mol Genet. 2014 Jul 15;23(14):3830-42
1	J:174490 Roussa E, Wiehle M, Dunker N, Becker-Katins S, Oehlke O, Krieglstein K, Transforming growth factor beta is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo: ectopic induction in dorsal mesencephalon. Stem Cells. 2006 Sep;24(9):2120-9
1	J:154113 Sacchetti P, Sousa KM, Hall AC, Liste I, Steffensen KR, Theofilopoulos S, Parish CL, Hazenberg C, Richter LA, Hovatta O, Gustafsson JA, Arenas E, Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells. Cell Stem Cell. 2009 Oct 2;5(4):409-19
1	J:205383 Salti A, Nat R, Neto S, Puschban Z, Wenning G, Dechant G, Expression of early developmental markers predicts the efficiency of embryonic stem cell differentiation into midbrain dopaminergic neurons. Stem Cells Dev. 2013 Feb 1;22(3):397-411
1	J:317430 Sharma D, Mirando AJ, Leinroth A, Long JT, Karner CM, Hilton MJ, HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly. PLoS Genet. 2021 Dec;17(12):e1009982
1*	J:276703 Shi J, Gao Q, Cao Y, Fu J, Dennd1a, a susceptibility gene for polycystic ovary syndrome, is essential for mouse embryogenesis. Dev Dyn. 2019 May;248(5):351-362
1	J:205284 Storer M, Mas A, Robert-Moreno A, Pecoraro M, Ortells MC, Di Giacomo V, Yosef R, Pilpel N, Krizhanovsky V, Sharpe J, Keyes WM, Senescence is a developmental mechanism that contributes to embryonic growth and patterning. Cell. 2013 Nov 21;155(5):1119-30
1*	J:166923 Wang B, Sinha T, Jiao K, Serra R, Wang J, Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B. Hum Mol Genet. 2011 Jan 15;20(2):271-85
1*	J:261953 Wang C, Wang J, Borer JG, Li X, Embryonic origin and remodeling of the urinary and digestive outlets. PLoS One. 2013;8(2):e55587
1*	J:165724 Yu S, Poe B, Schwarz M, Elliot SA, Albertine KH, Fenton S, Garg V, Moon AM, Fetal and postnatal lung defects reveal a novel and required role for Fgf8 in lung development. Dev Biol. 2010 Nov 1;347(1):92-108
1	J:264530 Zaffran S, Odelin G, Stefanovic S, Lescroart F, Etchevers HC, Ectopic expression of Hoxb1 induces cardiac and craniofacial malformations. Genesis. 2018 Jun;56(6-7):e23221