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Gene Expression Literature Summary
Assay
Age
RT-PCR
11.5 DPC

16 matching records from 16 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Col2a1  collagen, type II, alpha 1   (Synonyms: Col2, Col2a, Col2a-1, Del1, Lpk, M100413, M100856, Rgsc413, Rgsc856)
Results  Reference
1J:316273 Bashur LA, Chen D, Chen Z, Liang B, Pardi R, Murakami S, Zhou G, Loss of jab1 in osteochondral progenitor cells severely impairs embryonic limb development in mice. J Cell Physiol. 2014 Nov;229(11):1607-17
1J:166182 Bruce SJ, Butterfield NC, Metzis V, Town L, McGlinn E, Wicking C, Inactivation of Patched1 in the mouse limb has novel inhibitory effects on the chondrogenic program. J Biol Chem. 2010 Sep 3;285(36):27967-81
1*J:149242 Cameron TL, Belluoccio D, Farlie PG, Brachvogel B, Bateman JF, Global comparative transcriptome analysis of cartilage formation in vivo. BMC Dev Biol. 2009;9:20
1J:308882 Dennison BJC, Larson ED, Fu R, Mo J, Fantauzzo KA, Srsf3 mediates alternative RNA splicing downstream of PDGFRalpha signaling in the facial mesenchyme. Development. 2021 Jul 15;148(14):dev199448
1*J:125386 Kim JS, Ryoo ZY, Chun JS, Cytokine-like 1 (CYTL1) Regulates the Chondrogenesis of Mesenchymal Cells. J Biol Chem. 2007 Oct 5;282(40):29359-67
1J:264111 Liu CF, Angelozzi M, Haseeb A, Lefebvre V, SOX9 is dispensable for the initiation of epigenetic remodeling and the activation of marker genes at the onset of chondrogenesis. Development. 2018 Jul 18;145(14):dev164459
1*J:82986 McClive PJ, Sinclair AH, Type II and Type IX Collagen Transcript Isoforms Are Expressed During Mouse Testis Development. Biol Reprod. 2003 May;68(5):1742-7
1*J:14821 Ng LJ, Tam PP, Cheah KS, Preferential expression of alternatively spliced mRNAs encoding type II procollagen with a cysteine-rich amino-propeptide in differentiating cartilage and nonchondrogenic tissues during early mouse development. Dev Biol. 1993 Oct;159(2):403-17
1*J:317548 Nishida S, Yoshizaki H, Yasui Y, Kuwahara T, Kiyokawa E, Kohno M, Collagen VI suppresses fibronectin-induced enteric neural crest cell migration by downregulation of focal adhesion proteins. Biochem Biophys Res Commun. 2018 Jan 1;495(1):1461-1467
1J:237505 Norrie JL, Li Q, Co S, Huang BL, Ding D, Uy JC, Ji Z, Mackem S, Bedford MT, Galli A, Ji H, Vokes SA, PRMT5 is essential for the maintenance of chondrogenic progenitor cells in the limb bud. Development. 2016 Dec 15;143(24):4608-4619
1J:345597 Quilez S, Dumontier E, Baim C, Kam J, Cloutier JF, Loss of Neogenin alters branchial arch development and leads to craniofacial skeletal defects. Front Cell Dev Biol. 2024;12:1256465
1J:247121 Rutkowski TP, Kohn A, Sharma D, Ren Y, Mirando AJ, Hilton MJ, HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage development. J Cell Sci. 2016 Jun 01;129(11):2145-55
1J:95959 Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'keefe RJ, Stein GS, Drissi MH, Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol. 2005 Apr;203(1):133-43
1J:241783 Tang L, Wu X, Zhang H, Lu S, Wu M, Shen C, Chen X, Wang Y, Wang W, Shen Y, Gu M, Ding X, Jin X, Fei J, Wang Z, A point mutation in Fgf9 impedes joint interzone formation leading to multiple synostoses syndrome. Hum Mol Genet. 2017 Apr 01;26(7):1280-1293
1J:316121 Wang JR, Wang CJ, Xu CY, Wu XK, Hong D, Shi W, Gong Y, Chen HX, Long F, Wu XM, Signaling Cascades Governing Cdc42-Mediated Chondrogenic Differentiation and Mensenchymal Condensation. Genetics. 2016 Mar;202(3):1055-69
1J:257921 Wang JS, Infante CR, Park S, Menke DB, PITX1 promotes chondrogenesis and myogenesis in mouse hindlimbs through conserved regulatory targets. Dev Biol. 2018 Feb 1;434(1):186-195

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory