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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
11.5 DPC

16 matching records from 16 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cxcr4  C-X-C motif chemokine receptor 4   (Synonyms: b2b220Clo, CD184, Cmkar4, fusin, PB-CKR, Sdf1r)
Results  Reference
1J:113151 Borrell V, Marin O, Meninges control tangential migration of hem-derived Cajal-Retzius cells via CXCL12/CXCR4 signaling. Nat Neurosci. 2006 Oct;9(10):1284-93
1J:167212 Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ, Subtypes of medulloblastoma have distinct developmental origins. Nature. 2010 Dec 23;468(7327):1095-9
1J:333567 Gonzalez-Meljem JM, Ivins S, Andoniadou CL, Le Tissier P, Scambler P, Martinez-Barbera JP, An expression and function analysis of the CXCR4/SDF-1 signalling axis during pituitary gland development. PLoS One. 2023;18(2):e0280001
1J:239364 Ivins S, Chappell J, Vernay B, Suntharalingham J, Martineau A, Mohun TJ, Scambler PJ, The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development. Dev Cell. 2015 May 26;33(4):455-68
1*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1*J:57676 McGrath KE, Koniski AD, Maltby KM, McGann JK, Palis J, Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4. Dev Biol. 1999 Sep 15;213(2):442-56
1*J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
1J:267985 Page M, Ridge L, Gold Diaz D, Tsogbayar T, Scambler PJ, Ivins S, Loss of CXCL12/CXCR4 signalling impacts several aspects of cardiovascular development but does not exacerbate Tbx1 haploinsufficiency. PLoS One. 2018;13(11):e0207251
1*J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*J:272319 Tiveron MC, Boutin C, Daou P, Moepps B, Cremer H, Expression and function of CXCR7 in the mouse forebrain. J Neuroimmunol. 2010;224(1-2):72-9
1J:286078 Whitman MC, Miyake N, Nguyen EH, Bell JL, Matos Ruiz PM, Chan WM, Di Gioia SA, Mukherjee N, Barry BJ, Bosley TM, Khan AO, Engle EC, Decreased ACKR3 (CXCR7) function causes oculomotor synkinesis in mice and humans. Hum Mol Genet. 2019 Sep 15;28(18):3113-3125
1J:266591 Whitman MC, Nguyen EH, Bell JL, Tenney AP, Gelber A, Engle EC, Loss of CXCR4/CXCL12 Signaling Causes Oculomotor Nerve Misrouting and Development of Motor Trigeminal to Oculomotor Synkinesis. Invest Ophthalmol Vis Sci. 2018 Oct 1;59(12):5201-5209
1J:204963 Yang S, Edman LC, Sanchez-Alcaniz JA, Fritz N, Bonilla S, Hecht J, Uhlen P, Pleasure SJ, Villaescusa JC, Marin O, Arenas E, Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons. Development. 2013 Nov;140(22):4554-64
1J:289516 Yang S, Toledo EM, Rosmaninho P, Peng C, Uhlen P, Castro DS, Arenas E, A Zeb2-miR-200c loop controls midbrain dopaminergic neuron neurogenesis and migration. Commun Biol. 2018;1:75
1J:331054 Zhang W, Yu J, Fu G, Li J, Huang H, Liu J, Yu D, Qiu M, Li F, ISL1/SHH/CXCL12 signaling regulates myogenic cell migration during mouse tongue development. Development. 2022 Nov 1;149(21):dev200788
1J:222550 Zhu Y, Matsumoto T, Nagasawa T, Mackay F, Murakami F, Chemokine Signaling Controls Integrity of Radial Glial Scaffold in Developing Spinal Cord and Consequential Proper Position of Boundary Cap Cells. J Neurosci. 2015 Jun 17;35(24):9211-24

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory