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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
11.5 DPC

10 matching records from 10 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cxcr4  C-X-C motif chemokine receptor 4   (Synonyms: b2b220Clo, CD184, Cmkar4, fusin, PB-CKR, Sdf1r)
Results  Reference
1J:98453 Ara T, Tokoyoda K, Okamoto R, Koni PA, Nagasawa T, The role of CXCL12 in the organ-specific process of artery formation. Blood. 2005 Apr 15;105(8):3155-61
1J:208337 Bodea GO, Spille JH, Abe P, Andersson AS, Acker-Palmer A, Stumm R, Kubitscheck U, Blaess S, Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system. Development. 2014 Feb;141(3):661-73
1J:239363 Cavallero S, Shen H, Yi C, Lien CL, Kumar SR, Sucov HM, CXCL12 Signaling Is Essential for Maturation of the Ventricular Coronary Endothelial Plexus and Establishment of Functional Coronary Circulation. Dev Cell. 2015 May 26;33(4):469-77
1*J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
1J:267985 Page M, Ridge L, Gold Diaz D, Tsogbayar T, Scambler PJ, Ivins S, Loss of CXCL12/CXCR4 signalling impacts several aspects of cardiovascular development but does not exacerbate Tbx1 haploinsufficiency. PLoS One. 2018;13(11):e0207251
1J:310651 Ridge LA, Kewbank D, Schutz D, Stumm R, Scambler PJ, Ivins S, Dual role for CXCL12 signaling in semilunar valve development. Cell Rep. 2021 Aug 24;36(8):109610
1*J:100909 Vasyutina E, Stebler J, Brand-Saberi B, Schulz S, Raz E, Birchmeier C, CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells. Genes Dev. 2005 Sep 15;19(18):2187-98
1J:286078 Whitman MC, Miyake N, Nguyen EH, Bell JL, Matos Ruiz PM, Chan WM, Di Gioia SA, Mukherjee N, Barry BJ, Bosley TM, Khan AO, Engle EC, Decreased ACKR3 (CXCR7) function causes oculomotor synkinesis in mice and humans. Hum Mol Genet. 2019 Sep 15;28(18):3113-3125
1J:266591 Whitman MC, Nguyen EH, Bell JL, Tenney AP, Gelber A, Engle EC, Loss of CXCR4/CXCL12 Signaling Causes Oculomotor Nerve Misrouting and Development of Motor Trigeminal to Oculomotor Synkinesis. Invest Ophthalmol Vis Sci. 2018 Oct 1;59(12):5201-5209
1J:204963 Yang S, Edman LC, Sanchez-Alcaniz JA, Fritz N, Bonilla S, Hecht J, Uhlen P, Pleasure SJ, Villaescusa JC, Marin O, Arenas E, Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons. Development. 2013 Nov;140(22):4554-64

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory