Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ddx4  DEAD box helicase 4   (Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 4, Mvh, mvh / m'vasa, VASA)
Results	Reference
1	J:335514 Bird AD, Frost ER, Bagheri-Fam S, Croft BM, Ryan JM, Zhao L, Koopman P, Harley VR, Somatic FGFR2 is Required for Germ Cell Maintenance in the Mouse Ovary. Endocrinology. 2023 Mar 13;164(5)
1	J:333943 Cen C, Chen J, Lin L, Chen M, Dong F, Shen Z, Cui X, Hou X, Gao F, Fancb deficiency causes premature ovarian insufficiency in mice. Biol Reprod. 2022 Sep 12;107(3):790-799
1	J:191131 Chen L, Faire M, Kissner MD, Laird DJ, Primordial germ cells and gastrointestinal stromal tumors respond distinctly to a cKit overactivating allele. Hum Mol Genet. 2013 Jan 15;22(2):313-27
1	J:305337 Chen M, Wang Y, Lin L, Dong F, Wu H, Bao S, Gao F, PRMT7 is involved in regulation of germ cell proliferation during embryonic stage. Biochem Biophys Res Commun. 2020 Dec 17;533(4):938-944
1	J:224163 Hu YC, Nicholls PK, Soh YQ, Daniele JR, Junker JP, van Oudenaarden A, Page DC, Licensing of primordial germ cells for gametogenesis depends on genital ridge signaling. PLoS Genet. 2015 Mar;11(3):e1005019
1	J:131838 Huang X, Andreu-Vieyra CV, York JP, Hatcher R, Lu T, Matzuk MM, Zhang P, Inhibitory phosphorylation of separase is essential for genome stability and viability of murine embryonic germ cells. PLoS Biol. 2008 Jan;6(1):e15
1	J:82464 Kimura T, Suzuki A, Fujita Y, Yomogida K, Lomeli H, Asada N, Ikeuchi M, Nagy A, Mak TW, Nakano T, Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production. Development. 2003 Apr;130(8):1691-700
1*	J:175228 Medeiros LA, Dennis LM, Gill ME, Houbaviy H, Markoulaki S, Fu D, White AC, Kirak O, Sharp PA, Page DC, Jaenisch R, Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14163-8
1	J:316523 Messiaen S, Le Bras A, Duquenne C, Barroca V, Moison D, Dechamps N, Doussau M, Bauchet AL, Guerquin MJ, Livera G, Essers J, Kanaar R, Habert R, Bernardino-Sgherri J, Rad54 is required for the normal development of male and female germ cells and contributes to the maintainance of their genome integrity after genotoxic stress. Cell Death Dis. 2013 Aug 15;4:e774
1*	J:176205 Moniot B, Farhat A, Aritake K, Declosmenil F, Nef S, Eguchi N, Urade Y, Poulat F, Boizet-Bonhoure B, Hematopoietic prostaglandin D synthase (H-Pgds) is expressed in the early embryonic gonad and participates to the initial nuclear translocation of the SOX9 protein. Dev Dyn. 2011 Oct;240(10):2335-43
1	J:172637 Park S, Zeidan K, Shin JS, Taketo T, SRY upregulation of SOX9 is inefficient and delayed, allowing ovarian differentiation, in the B6.Y(TIR) gonad. Differentiation. 2011 Jul;82(1):18-27
1*	J:189072 Spiller CM, Feng CW, Jackson A, Gillis AJ, Rolland AD, Looijenga LH, Koopman P, Bowles J, Endogenous Nodal signaling regulates germ cell potency during mammalian testis development. Development. 2012 Nov;139(22):4123-32
1	J:324297 Thomson E, Zhao L, Chen YS, Longmuss E, Ng ET, Sreenivasan R, Croft B, Song X, Sinclair A, Weiss M, Koopman P, Pelosi E, Generation and mutational analysis of a transgenic mouse model of human SRY. Hum Mutat. 2022 Mar;43(3):362-379
1*	J:62087 Toyooka Y, Tsunekawa N, Takahashi Y, Matsui Y, Satoh M, Noce T, Expression and intracellular localization of mouse Vasa-homologue protein during germ cell development. Mech Dev. 2000 May;93(1-2):139-49
1	J:277545 Wang Y, Li Q, Liu C, Han F, Chen M, Zhang L, Cui X, Qin Y, Bao S, Gao F, Protein arginine methyltransferase 5 (Prmt5) is required for germ cell survival during mouse embryonic development. Biol Reprod. 2015 Apr;92(4):104
1	J:320185 Windley SP, Mayere C, McGovern AE, Harvey NL, Nef S, Schwarz Q, Kumar S, Wilhelm D, Loss of NEDD4 causes complete XY gonadal sex reversal in mice. Cell Death Dis. 2022 Jan 24;13(1):75
1	J:223223 Wu Q, Fukuda K, Weinstein M, Graff JM, Saga Y, SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice. Development. 2015 Feb 1;142(3):575-86
1*	J:302181 Xu Y, Xie J, Etomoxir regulates the differentiation of male germ cells by specifically reducing H3K27ac level. BMC Dev Biol. 2021 Feb 1;21(1):5
1	J:237560 Yamashiro C, Hirota T, Kurimoto K, Nakamura T, Yabuta Y, Nagaoka SI, Ohta H, Yamamoto T, Saitou M, Persistent Requirement and Alteration of the Key Targets of PRDM1 During Primordial Germ Cell Development in Mice. Biol Reprod. 2016 Jan;94(1):7
1*	J:306910 Yu DCW, Wu FC, Wu CE, Chow LP, Ho HN, Chen HF, Human pluripotent stem cell-derived DDX4 and KRT-8 positive cells participate in ovarian follicle-like structure formation. iScience. 2021 Jan 22;24(1):102003
1	J:274106 Zaqout S, Bessa P, Kramer N, Stoltenburg-Didinger G, Kaindl AM, CDK5RAP2 Is Required to Maintain the Germ Cell Pool during Embryonic Development. Stem Cell Reports. 2017 Feb 14;8(2):198-204
1	J:316098 Zhao J, Lu P, Wan C, Huang Y, Cui M, Yang X, Hu Y, Zheng Y, Dong J, Wang M, Zhang S, Liu Z, Bian S, Wang X, Wang R, Ren S, Wang D, Yao Z, Chang G, Tang F, Zhao XY, Cell-fate transition and determination analysis of mouse male germ cells throughout development. Nat Commun. 2021 Nov 25;12(1):6839
1	J:318865 Zheng B, Zhao D, Zhang P, Shen C, Guo Y, Zhou T, Guo X, Zhou Z, Sha J, Quantitative Proteomics Reveals the Essential Roles of Stromal Interaction Molecule 1 (STIM1) in the Testicular Cord Formation in Mouse Testis. Mol Cell Proteomics. 2015 Oct;14(10):2682-91