Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hbb-y  hemoglobin Y, beta-like embryonic chain   (Synonyms: epsilon Y globin, Ey, Hby)
Results	Reference
1*	J:175394 Alhashem YN, Vinjamur DS, Basu M, Klingmuller U, Gaensler KM, Lloyd JA, Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding. J Biol Chem. 2011 Jul 15;286(28):24819-27
1	J:149115 Basu P, Lung TK, Lemsaddek W, Sargent TG, Williams DC Jr, Basu M, Redmond LC, Lingrel JB, Haar JL, Lloyd JA, EKLF and KLF2 have compensatory roles in embryonic beta-globin gene expression and primitive erythropoiesis. Blood. 2007 Nov 1;110(9):3417-25
1*	J:119377 Basu P, Morris PE, Haar JL, Wani MA, Lingrel JB, Gaensler KM, Lloyd JA, KLF2 is essential for primitive erythropoiesis and regulates the human and murine embryonic beta-like globin genes in vivo. Blood. 2005 Oct 1;106(7):2566-71
1*	J:49955 Belaoussoff M, Farrington SM, Baron MH, Hematopoietic induction and respecification of A-P identity by visceral endoderm signaling in the mouse embryo. Development. 1998 Dec;125(24):5009-18
1	J:166627 Feng Y, Yang Y, Ortega MM, Copeland JN, Zhang M, Jacob JB, Fields TA, Vivian JL, Fields PE, Early mammalian erythropoiesis requires the Dot1L methyltransferase. Blood. 2010 Nov 25;116(22):4483-91
1*	J:28981 Fiering S, Epner E, Robinson K, Zhuang Y, Telling A, Hu M, Martin DI, Enver T, Ley TJ, Groudine M, Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus. Genes Dev. 1995 Sep 15;9(18):2203-13
1	J:204573 Funnell AP, Mak KS, Twine NA, Pelka GJ, Norton LJ, Radziewic T, Power M, Wilkins MR, Bell-Anderson KS, Fraser ST, Perkins AC, Tam PP, Pearson RC, Crossley M, Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing. Mol Cell Biol. 2013 Aug;33(15):2976-87
1*	J:33053 Hug BA, Wesselschmidt RL, Fiering S, Bender MA, Epner E, Groudine M, Ley TJ, Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3. Mol Cell Biol. 1996 Jun;16(6):2906-12
1	J:133333 Kingsley PD, Malik J, Emerson RL, Bushnell TP, McGrath KE, Bloedorn LA, Bulger M, Palis J, 'Maturational' globin switching in primary primitive erythroid cells. Blood. 2006 Feb 15;107(4):1665-72
1	J:345473 Lee JG, Yon JM, Kim G, Lee SG, Kim CY, Cheong SA, Kim HY, Yu J, Kim K, Sung YH, Yoo HJ, Woo DC, Rho JK, Ha CH, Pack CG, Oh SH, Lim JS, Han YM, Hong EJ, Seong JK, Lee HW, Lee SW, Lee KU, Kim CJ, Nam SY, Cho YS, Baek IJ, PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development. Nat Commun. 2024 Feb 19;15(1):1487
1	J:153993 Liang SY, Moghimi B, Crusselle-Davis VJ, Lin IJ, Rosenberg MH, Li X, Strouboulis J, Huang S, Bungert J, Defective erythropoiesis in transgenic mice expressing dominant-negative upstream stimulatory factor. Mol Cell Biol. 2009 Nov;29(21):5900-10
1	J:244545 Peraki I, Palis J, Mavrothalassitis G, The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive Hematopoiesis. Mol Cell Biol. 2017 Oct 01;37(19)
1	J:204328 Tondeleir D, Drogat B, Slowicka K, Bakkali K, Bartunkova S, Goossens S, Haigh JJ, Ampe C, Beta-Actin Is Involved in Modulating Erythropoiesis during Development by Fine-Tuning Gata2 Expression Levels. PLoS One. 2013;8(6):e67855
1	J:310313 Vinjamur DS, Wade KJ, Mohamad SF, Haar JL, Sawyer ST, Lloyd JA, Kruppel-like transcription factors KLF1 and KLF2 have unique and coordinate roles in regulating embryonic erythroid precursor maturation. Haematologica. 2014 Oct;99(10):1565-73
1	J:127025 Yasuda Y, Sasaki T, Takagawa M, Maeda M, Yasuda M, Atsumi T, Fujita Y, Fujita H, Erythropoietin contributes to implantation: ectopic hemoglobin synthesis in decidual cells of mice. Congenit Anom (Kyoto). 2007 Mar;47(1):22-33