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Gene Expression Literature Summary
Assay
Age
RT-PCR
10.5 DPC

9 matching records from 9 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Nr5a1  nuclear receptor subfamily 5, group A, member 1   (Synonyms: Ad4BP, adrenal 4-binding protein, ELP, Ftzf1, Ftz-F1, SF1, SF-1, steroidogenic factor 1)
Results  Reference
1J:158334 Combes AN, Spiller CM, Harley VR, Sinclair AH, Dunwoodie SL, Wilhelm D, Koopman P, Gonadal defects in Cited2-mutant mice indicate a role for SF1 in both testis and ovary differentiation. Int J Dev Biol. 2010;54(4):683-9
1*J:183829 Correa SM, Washburn LL, Kahlon RS, Musson MC, Bouma GJ, Eicher EM, Albrecht KH, Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway. PLoS Genet. 2012 Apr;8(4):e1002569
1J:204550 Fujimoto Y, Tanaka SS, Yamaguchi YL, Kobayashi H, Kuroki S, Tachibana M, Shinomura M, Kanai Y, Morohashi K, Kawakami K, Nishinakamura R, Homeoproteins Six1 and Six4 regulate male sex determination and mouse gonadal development. Dev Cell. 2013 Aug 26;26(4):416-30
1J:191095 Gierl MS, Gruhn WH, von Seggern A, Maltry N, Niehrs C, GADD45G functions in male sex determination by promoting p38 signaling and Sry expression. Dev Cell. 2012 Nov 13;23(5):1032-42
1*J:148612 Jin Z, Liu L, Bian W, Chen Y, Xu G, Cheng L, Jing N, Different transcription factors regulate nestin gene expression during P19 cell neural differentiation and central nervous system development. J Biol Chem. 2009 Mar 20;284(12):8160-73
1J:178424 Kashimada K, Svingen T, Feng CW, Pelosi E, Bagheri-Fam S, Harley VR, Schlessinger D, Bowles J, Koopman P, Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice. FASEB J. 2011 Oct;25(10):3561-9
1J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27
1J:135126 Val P, Martinez-Barbera JP, Swain A, Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage. Development. 2007 Jun;134(12):2349-58
1J:77996 Wilhelm D, Englert C, The Wilms tumor suppressor WT1 regulates early gonad development by activation of Sf1. Genes Dev. 2002 Jul 15;16(14):1839-51

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory