Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cdh5  cadherin 5   (Synonyms: 7B4/cadherin-5, CD144, VEC, VEcad, VE-Cad, VE-cadherin, VECD)
Results	Reference
1	J:213517 Azzoni E, Conti V, Campana L, Dellavalle A, Adams RH, Cossu G, Brunelli S, Hemogenic endothelium generates mesoangioblasts that contribute to several mesodermal lineages in vivo. Development. 2014 May;141(9):1821-34
1	J:137137 Carlson TR, Hu H, Braren R, Kim YH, Wang RA, Cell-autonomous requirement for {beta}1 integrin in endothelial cell adhesion, migration and survival during angiogenesis in mice. Development. 2008 Jun;135(12):2193-202
1	J:85505 Cattelino A, Liebner S, Gallini R, Zanetti A, Balconi G, Corsi A, Bianco P, Wolburg H, Moore R, Oreda B, Kemler R, Dejana E, The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility. J Cell Biol. 2003 Sep 15;162(6):1111-22
1	J:224419 Clouthier DL, Harris CN, Harris RA, Martin CE, Puri MC, Jones N, Requisite role for Nck adaptors in cardiovascular development, endothelial-to-mesenchymal transition, and directed cell migration. Mol Cell Biol. 2015 May;35(9):1573-87
1	J:263837 Dave JM, Mirabella T, Weatherbee SD, Greif DM, Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain. Dev Cell. 2018 Mar 26;44(6):665-678.e6
1	J:143564 Francois M, Caprini A, Hosking B, Orsenigo F, Wilhelm D, Browne C, Paavonen K, Karnezis T, Shayan R, Downes M, Davidson T, Tutt D, Cheah KS, Stacker SA, Muscat GE, Achen MG, Dejana E, Koopman P, Sox18 induces development of the lymphatic vasculature in mice. Nature. 2008 Dec 4;456(7222):643-7
1	J:303664 Gama Sosa MA, De Gasperi R, Perez GM, Hof PR, Elder GA, Hemovasculogenic origin of blood vessels in the developing mouse brain. J Comp Neurol. 2021 Feb;529(2):340-366
1	J:70266 Graef IA, Chen F, Chen L, Kuo A, Crabtree GR, Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature. Cell. 2001 Jun 29;105(7):863-75
1	J:307823 Hoover C, Kondo Y, Shao B, McDaniel MJ, Lee R, McGee S, Whiteheart S, Bergmeier W, McEver RP, Xia L, Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin. Blood. 2021 May 20;137(20):2756-2769
1	J:207517 Ingram KG, Curtis CD, Silasi-Mansat R, Lupu F, Griffin CT, The NuRD chromatin-remodeling enzyme CHD4 promotes embryonic vascular integrity by transcriptionally regulating extracellular matrix proteolysis. PLoS Genet. 2013 Dec;9(12):e1004031
1	J:340487 Kazenwadel J, Venugopal P, Oszmiana A, Toubia J, Arriola-Martinez L, Panara V, Piltz SG, Brown C, Ma W, Schreiber AW, Koltowska K, Taoudi S, Thomas PQ, Scott HS, Harvey NL, A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature. Nature. 2023 Feb;614(7947):343-348
1	J:344312 Liu H, Zhou R, Li S, Dong J, Fang Y, Luo Y, Su H, Lai B, Liang L, Zhang D, Zhang Y, Shyy JY, Zhou B, Yuan Z, Wang Y, Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development. iScience. 2024 Jan 19;27(1):108722
1	J:219728 Liu Q, Hu T, He L, Huang X, Tian X, Zhang H, He L, Pu W, Zhang L, Sun H, Fang J, Yu Y, Duan S, Hu C, Hui L, Zhang H, Quertermous T, Xu Q, Red-Horse K, Wythe JD, Zhou B, Genetic targeting of sprouting angiogenesis using Apln-CreER. Nat Commun. 2015;6:6020
1	J:224446 Lizama CO, Hawkins JS, Schmitt CE, Bos FL, Zape JP, Cautivo KM, Borges Pinto H, Rhyner AM, Yu H, Donohoe ME, Wythe JD, Zovein AC, Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition. Nat Commun. 2015;6:7739
1	J:327182 Moulis M, Runser SVM, Glorieux L, Dauguet N, Vanderaa C, Gatto L, Tyteca D, Henriet P, Spagnoli FM, Iber D, Pierreux CE, Identification and implication of tissue-enriched ligands in epithelial-endothelial crosstalk during pancreas development. Sci Rep. 2022 Jul 21;12(1):12498
1	J:170867 Oas RG, Xiao K, Summers S, Wittich KB, Chiasson CM, Martin WD, Grossniklaus HE, Vincent PA, Reynolds AB, Kowalczyk AP, p120-Catenin is required for mouse vascular development. Circ Res. 2010 Mar 19;106(5):941-51
1*	J:315091 Roques M, Durand C, Gautier R, Canto PY, Petit-Cocault L, Yvernogeau L, Dunon D, Souyri M, Jaffredo T, Endoglin expression level discriminates long-term hematopoietic from short-term clonogenic progenitor cells in the aorta. Haematologica. 2012 Jul;97(7):975-9
1	J:195902 Rossdeutsch A, Smart N, Dube KN, Turner M, Riley PR, Essential role for thymosin beta4 in regulating vascular smooth muscle cell development and vessel wall stability. Circ Res. 2012 Aug 3;111(4):e89-102
1*	J:316590 Rybtsov S, Batsivari A, Bilotkach K, Paruzina D, Senserrich J, Nerushev O, Medvinsky A, Tracing the origin of the HSC hierarchy reveals an SCF-dependent, IL-3-independent CD43(-) embryonic precursor. Stem Cell Reports. 2014 Sep 9;3(3):489-501
1	J:314577 Shao X, Liu K, Fan Y, Ding Z, Chen M, Zhu M, Weinstein LS, Li H, Li H, Galphas Relays Sphingosine-1-Phosphate Receptor 1 Signaling to Stabilize Vascular Endothelial-Cadherin at Endothelial Junctions to Control Mouse Embryonic Vascular Integrity. J Genet Genomics. 2015 Nov 20;42(11):613-624
1	J:142352 Stenman JM, Rajagopal J, Carroll TJ, Ishibashi M, McMahon J, McMahon AP, Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature. Science. 2008 Nov 21;322(5905):1247-50
1*	J:341715 Sui Y, Kou S, Ge K, Cao J, Liu C, Zhang H, Expression analysis of plvap in mouse heart development, homeostasis and injury. Gene Expr Patterns. 2023 Sep 28;50:119343
1	J:296040 Takahashi S, Nobuhisa I, Saito K, Gerel M, Itabashi A, Harada K, Osawa M, Endo TA, Iwama A, Taga T, Sox17-mediated expression of adherent molecules is required for the maintenance of undifferentiated hematopoietic cluster formation in midgestation mouse embryos. Differentiation. 2020 Sep - Oct;115:53-61
1	J:188920 Vijayaraj P, Le Bras A, Mitchell N, Kondo M, Juliao S, Wasserman M, Beeler D, Spokes K, Aird WC, Baldwin HS, Oettgen P, Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis. Development. 2012 Nov;139(21):3973-85
1*	J:57646 Wigle JT, Oliver G, Prox1 function is required for the development of the murine lymphatic system. Cell. 1999 Sep 17;98(6):769-78
1	J:191306 Yang Y, Garcia-Verdugo JM, Soriano-Navarro M, Srinivasan RS, Scallan JP, Singh MK, Epstein JA, Oliver G, Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos. Blood. 2012 Sep 13;120(11):2340-8
1	J:262529 Zhang H, Huang X, Liu K, Tang J, He L, Pu W, Liu Q, Li Y, Tian X, Wang Y, Zhang L, Yu Y, Wang H, Hu R, Wang F, Chen T, Wang QD, Qiao Z, Zhang L, Lui KO, Zhou B, Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium. Cell Res. 2017 Sep;27(9):1157-1177
1*	J:256775 Zhang H, Pu W, Li G, Huang X, He L, Tian X, Liu Q, Zhang L, Wu SM, Sucov HM, Zhou B, Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls. Circ Res. 2016 Jun 10;118(12):1880-93
1	J:231966 Zhang H, Pu W, Tian X, Huang X, He L, Liu Q, Li Y, Zhang L, He L, Liu K, Gillich A, Zhou B, Genetic lineage tracing identifies endocardial origin of liver vasculature. Nat Genet. 2016 May;48(5):537-43