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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
10 DPC

7 matching records from 7 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Fgf4  fibroblast growth factor 4   (Synonyms: Fgf-4, Fgfk, Hst1, Hstf-1, kFGF)
Results  Reference
1J:29274 Chan DC, Wynshaw-Boris A, Leder P, Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud. Development. 1995 Oct;121(10):3151-62
1J:104411 Lu P, Minowada G, Martin GR, Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function. Development. 2006 Jan;133(1):33-42
1J:27442 Masuya H, Sagai T, Wakana S, Moriwaki K, Shiroishi T, A duplicated zone of polarizing activity in polydactylous mouse mutants. Genes Dev. 1995 Jul 1;9(13):1645-53
1J:91163 Mic FA, Sirbu IO, Duester G, Retinoic acid synthesis controlled by Raldh2 is required early for limb bud initiation and then later as a proximodistal signal during apical ectodermal ridge formation. J Biol Chem. 2004 Jun 18;279(25):26698-706
1*J:60091 Moon AM, Boulet AM, Capecchi MR, Normal limb development in conditional mutants of Fgf4. Development. 2000 Mar;127(5):989-96
1J:61886 Sun X, Lewandoski M, Meyers EN, Liu YH, Maxson RE Jr, Martin GR, Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development. Nat Genet. 2000 May;25(1):83-6
1J:58039 Zuniga A, Haramis AP, McMahon AP, Zeller R, Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds. Nature. 1999 Oct 7;401(6753):598-602

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory