Gene Expression Literature Summary

• Symbol: Txn1
• Name: thioredoxin 1
• ID: MGI:98874

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E9	E10.5	E11.5	E12.5	E13.5	E14.5	E15	E16.5	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)	2		3	3	1	3	1		3			1	1	3
In situ RNA (section)							1
Western blot		1						1					2	3
RT-PCR								1		1	1		1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Txn1  thioredoxin 1   (Synonyms: Trx1)
Results	Reference
4*	J:150363 Chung YW, Jeong D, Noh OJ, Park YH, Kang SI, Lee MG, Lee TH, Yim MB, Kim IY, Antioxidative role of selenoprotein W in oxidant-induced mouse embryonic neuronal cell death. Mol Cells. 2009 May;27(5):609-13
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2	J:163352 Kamimoto Y, Sugiyama T, Kihira T, Zhang L, Murabayashi N, Umekawa T, Nagao K, Ma N, Toyoda N, Yodoi J, Sagawa N, Transgenic mice overproducing human thioredoxin-1, an antioxidative and anti-apoptotic protein, prevents diabetic embryopathy. Diabetologia. 2010 Sep;53(9):2046-55
6	J:74095 Kobayashi M, Nakamura H, Yodoi J, Shiota K, Immunohistochemical localization of thioredoxin and glutaredoxin in mouse embryos and fetuses. Antioxid Redox Signal. 2000 Winter;2(4):653-63
5	J:74208 Kobayashi M, Nakamura H, Yodoi J, Shiota K, Ontogenesis of anti-oxidative enzymes in mouse embryos and fetuses: an immunohistochemical study. Ital J Anat Embryol. 2001;106(2 Suppl 2):137-42
8*	J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617
1	J:176499 Rederstorff M, Castets P, Arbogast S, Laine J, Vassilopoulos S, Beuvin M, Dubourg O, Vignaud A, Ferry A, Krol A, Allamand V, Guicheney P, Ferreiro A, Lescure A, Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy. PLoS One. 2011;6(8):e23094
6	J:138125 Umekawa T, Sugiyama T, Kihira T, Murabayashi N, Zhang L, Nagao K, Kamimoto Y, Ma N, Yodoi J, Sagawa N, Overexpression of thioredoxin-1 reduces oxidative stress in the placenta of transgenic mice and promotes fetal growth via glucose metabolism. Endocrinology. 2008 Aug;149(8):3980-8
1	J:226104 Wang F, Wu Y, Quon MJ, Li X, Yang P, ASK1 mediates the teratogenicity of diabetes in the developing heart by inducing ER stress and inhibiting critical factors essential for cardiac development. Am J Physiol Endocrinol Metab. 2015 Sep 1;309(5):E487-99
1*	J:260330 Yang P, Li X, Xu C, Eckert RL, Reece EA, Zielke HR, Wang F, Maternal hyperglycemia activates an ASK1-FoxO3a-caspase 8 pathway that leads to embryonic neural tube defects. Sci Signal. 2013 Aug 27;6(290):ra74