Gene Expression Literature Summary

• Symbol: Srsf2
• Name: serine and arginine-rich splicing factor 2
• ID: MGI:98284

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E3.5	E5	E6	E7	E7.5	E9	E11	E11.5	E12.5	E13.5	E15.5	E16.5	E18.5	P
Immunohistochemistry (section)	1		1												1		3
In situ RNA (section)											1		1		1		1
Immunohistochemistry (whole mount)	2	2	1	1													1
Northern blot					1	1	1		1	1							1
RT-PCR					1			1				1	2	1	1	1	3
cDNA clones								1									1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Srsf2  serine and arginine-rich splicing factor 2   (Synonyms: D11Wsu175e, MRF-1, SC35, Sfrs10, Sfrs2)
Results	Reference
4*	J:222615 Abe K, Yamamoto R, Franke V, Cao M, Suzuki Y, Suzuki MG, Vlahovicek K, Svoboda P, Schultz RM, Aoki F, The first murine zygotic transcription is promiscuous and uncoupled from splicing and 3' processing. EMBO J. 2015 Jun 3;34(11):1523-37
1*	J:88432 Ding JH, Xu X, Yang D, Chu PH, Dalton ND, Ye Z, Yeakley JM, Cheng H, Xiao RP, Ross J, Chen J, Fu XD, Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. EMBO J. 2004 Feb 25;23(4):885-96
1	J:23142 Ferreira J, Carmo-Fonseca M, The biogenesis of the coiled body during early mouse development. Development. 1995 Feb;121(2):601-12
1*	J:137989 Hahn P, Bose J, Edler S, Lengeling A, Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteins. BMC Genomics. 2008;9:293
2*	J:50869 Ko MSH, Threat TA, Wang X, Horton JH, Cui Y, Pryor E, Paris J , Wells-Smith J , Kitchen JR , Rowe LB , Eppig J , Satoh T , Brant L , Fujiwara H , Yotsumoto S , Nakashima H, Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
1*	J:109158 Leu S, Ouyang P, Spatial and temporal expression profile of pinin during mouse development. Gene Expr Patterns. 2006 Aug;6(6):620-31
2	J:206588 Mardaryev AN, Gdula MR, Yarker JL, Emelianov VN, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Chambon P, Botchkarev VA, Fessing MY, p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells. Development. 2014 Jan;141(1):101-11
4*	J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
2*	J:305251 Meinke S, Goldammer G, Weber AI, Tarabykin V, Neumann A, Preussner M, Heyd F, Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression. Elife. 2020 Apr 27;9:e56075
9*	J:66654 Nie GY, Li Y, Batten L, Griffiths B, Wang J, Findlay JK, Salamonsen LA, Uterine expression of alternatively spliced mRNAs of mouse splicing factor SC35 during early pregnancy. Mol Hum Reprod. 2000 Dec;6(12):1131-9
1*	J:86824 Payer B, Saitou M, Barton SC, Thresher R, Dixon JP, Zahn D, Colledge WH, Carlton MB, Nakano T, Surani MA, stella is a maternal effect gene required for normal early development in mice. Curr Biol. 2003 Dec 2;13(23):2110-7
1*	J:320422 Petit FG, Jamin SP, Kernanec PY, Becker E, Halet G, Primig M, EXOSC10/Rrp6 is essential for the eight-cell embryo/morula transition. Dev Biol. 2022 Mar;483:58-65
1	J:163097 Thoren LA, Norgaard GA, Weischenfeldt J, Waage J, Jakobsen JS, Damgaard I, Bergstrom FC, Blom AM, Borup R, Bisgaard HC, Porse BT, UPF2 is a critical regulator of liver development, function and regeneration. PLoS One. 2010;5(7):e11650
3	J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918
2*	J:336921 Younis S, Jouneau A, Larsson M, Oudin JF, Adenot P, Omar J, Brochard V, Andersson L, Ablation of ZC3H11A causes early embryonic lethality and dysregulation of metabolic processes. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2216799120
1	J:324155 Zhang J, Liu W, Li G, Xu C, Nie X, Qin D, Wang Q, Lu X, Liu J, Li L, BCAS2 is involved in alternative splicing and mouse oocyte development. FASEB J. 2022 Feb;36(2):e22128