Gene Expression Literature Summary

• Symbol: Rcvrn
• Name: recoverin
• ID: MGI:97883

73 matching records from 73 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E12.5	E15	E15.5	E16.5	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)	2		1	1	1		4	1	60
In situ RNA (section)									1
Northern blot									1
Western blot									1
RT-PCR		1				1			9

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Rcvrn  recoverin   (Synonyms: cancer associated retinopathy protein, guanylate cyclase activator, S-modulin)
Results	Reference
3*	J:242163 Aavani T, Tachibana N, Wallace V, Biernaskie J, Schuurmans C, Temporal profiling of photoreceptor lineage gene expression during murine retinal development. Gene Expr Patterns. 2017 Jan;23-24:32-44
1	J:103009 Acosta ML, Kalloniatis M, Christie DL, Creatine transporter localization in developing and adult retina: importance of creatine to retinal function. Am J Physiol Cell Physiol. 2005 Oct;289(4):C1015-23
1	J:240005 Aldiri I, Ajioka I, Xu B, Zhang J, Chen X, Benavente C, Finkelstein D, Johnson D, Akiyama J, Pennacchio LA, Dyer MA, Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma. Development. 2015 Dec 01;142(23):4092-106
1*	J:191149 Alves CH, Sanz Sanz A, Park B, Pellissier LP, Tanimoto N, Beck SC, Huber G, Murtaza M, Richard F, Sridevi Gurubaran I, Garcia Garrido M, Levelt CN, Rashbass P, Le Bivic A, Seeliger MW, Wijnholds J, Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. Hum Mol Genet. 2013 Jan 1;22(1):35-50
1*	J:132131 Barton KM, Levine EM, Expression patterns and cell cycle profiles of PCNA, MCM6, cyclin D1, cyclin A2, cyclin B1, and phosphorylated histone H3 in the developing mouse retina. Dev Dyn. 2008 Mar;237(3):672-82
1	J:238712 Belanger MC, Robert B, Cayouette M, Msx1-Positive Progenitors in the Retinal Ciliary Margin Give Rise to Both Neural and Non-neural Progenies in Mammals. Dev Cell. 2017 Jan 23;40(2):137-150
1	J:70746 Brown NL, Patel S, Brzezinski J, Glaser T, Math5 is required for retinal ganglion cell and optic nerve formation. Development. 2001 Jul;128(13):2497-508
1	J:156665 Brzezinski JA 4th, Lamba DA, Reh TA, Blimp1 controls photoreceptor versus bipolar cell fate choice during retinal development. Development. 2010 Feb;137(4):619-29
1	J:174095 Cai Z, Simons DL, Fu XY, Feng GS, Wu SM, Zhang X, Loss of shp2-mediated mitogen-activated protein kinase signaling in muller glial cells results in retinal degeneration. Mol Cell Biol. 2011 Jul;31(14):2973-83
1	J:302526 Cao X, An J, Cao Y, Lv J, Wang J, Ding Y, Lin X, Zhou X, EMC3 Is Essential for Retinal Organization and Neurogenesis During Mouse Retinal Development. Invest Ophthalmol Vis Sci. 2021 Feb 1;62(2):31
1	J:294396 Chang KC, Sun C, Cameron EG, Madaan A, Wu S, Xia X, Zhang X, Tenerelli K, Nahmou M, Knasel CM, Russano KR, Hertz J, Goldberg JL, Opposing Effects of Growth and Differentiation Factors in Cell-Fate Specification. Curr Biol. 2019 Jun 17;29(12):1963-1975.e5
1	J:103461 Cheng CW, Chow RL, Lebel M, Sakuma R, Cheung HO, Thanabalasingham V, Zhang X, Bruneau BG, Birch DG, Hui CC, McInnes RR, Cheng SH, The Iroquois homeobox gene, Irx5, is required for retinal cone bipolar cell development. Dev Biol. 2005 Nov 1;287(1):48-60
1*	J:73287 Chow RL, Snow B, Novak J, Looser J, Freund C, Vidgen D, Ploder L, McInnes RR, Vsx1, a rapidly evolving paired-like homeobox gene expressed in cone bipolar cells. Mech Dev. 2001 Dec;109(2):315-22
1	J:248927 Clements R, Turk R, Campbell KP, Wright KM, Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development. J Neurosci. 2017 Aug 30;37(35):8559-8574
1	J:297748 Collin GB, Won J, Krebs MP, Hicks WJ, Charette JR, Naggert JK, Nishina PM, Disruption in murine Eml1 perturbs retinal lamination during early development. Sci Rep. 2020 Mar 27;10(1):5647
1*	J:107820 Corbo JC, Cepko CL, A Hybrid Photoreceptor Expressing Both Rod and Cone Genes in a Mouse Model of Enhanced S-Cone Syndrome. PLoS Genet. 2005 Aug 5;1(2):e11
1	J:171198 Cwinn MA, Mazerolle C, McNeill B, Ringuette R, Thurig S, Hui CC, Wallace VA, Suppressor of fused is required to maintain the multipotency of neural progenitor cells in the retina. J Neurosci. 2011 Mar 30;31(13):5169-80
1	J:160729 Das G, Choi Y, Sicinski P, Levine EM, Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells. Neural Dev. 2009;4:15
1*	J:214586 Duan X, Krishnaswamy A, De la Huerta I, Sanes JR, Type II cadherins guide assembly of a direction-selective retinal circuit. Cell. 2014 Aug 14;158(4):793-807
1	J:189829 Edqvist PH, Niklasson M, Vidal-Sanz M, Hallbook F, Forsberg-Nilsson K, Platelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation. PLoS One. 2012;7(8):e42488
1	J:134563 Elshatory Y, Deng M, Xie X, Gan L, Expression of the LIM-homeodomain protein Isl1 in the developing and mature mouse retina. J Comp Neurol. 2007 Jul 1;503(1):182-97
1	J:119663 Feng L, Xie X, Joshi PS, Yang Z, Shibasaki K, Chow RL, Gan L, Requirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retina. Development. 2006 Dec;133(24):4815-25
1	J:168595 Feng L, Xie ZH, Ding Q, Xie X, Libby RT, Gan L, MATH5 controls the acquisition of multiple retinal cell fates. Mol Brain. 2010;3:36
1	J:159105 Georgi SA, Reh TA, Dicer is required for the transition from early to late progenitor state in the developing mouse retina. J Neurosci. 2010 Mar 17;30(11):4048-61
1	J:249145 Goetz JJ, Laboissonniere LA, Wester AK, Lynch MR, Trimarchi JM, Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression. PLoS One. 2016;11(3):e0150878
1	J:135649 Horvat-Brocker A, Reinhard J, Illes S, Paech T, Zoidl G, Harroch S, Distler C, Knyazev P, Ullrich A, Faissner A, Receptor protein tyrosine phosphatases are expressed by cycling retinal progenitor cells and involved in neuronal development of mouse retina. Neuroscience. 2008 Mar 27;152(3):618-45
1	J:242258 Iida A, Iwagawa T, Baba Y, Satoh S, Mochizuki Y, Nakauchi H, Furukawa T, Koseki H, Murakami A, Watanabe S, Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation. Dev Neurobiol. 2015 Sep;75(9):947-60
1	J:337791 Iwagawa T, Fukushima M, Takeuchi S, Kawamura Y, Aihara Y, Ozawa M, Yakushiji-Kaminatsui N, Aihara M, Koseki H, Suzuki Y, Watanabe S, The histone H3K36 demethylase Fbxl11 plays pivotal roles in the development of retinal late-born cell types. Genes Cells. 2023 Jul;28(7):482-495
1	J:164295 Jin K, Jiang H, Mo Z, Xiang M, Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors. J Neurosci. 2010 Sep 8;30(36):11902-16
1	J:302827 Jin K, Jiang H, Xiao D, Zou M, Zhu J, Xiang M, Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis. Mol Brain. 2015 May 13;8:28
1	J:152506 Jin ZB, Hirokawa G, Gui L, Takahashi R, Osakada F, Hiura Y, Takahashi M, Yasuhara O, Iwai N, Targeted deletion of miR-182, an abundant retinal microRNA. Mol Vis. 2009;15:523-33
1	J:181926 Jo HS, Kang KH, Joe CO, Kim JW, Pten coordinates retinal neurogenesis by regulating Notch signalling. EMBO J. 2012 Feb 15;31(4):817-28
1	J:193195 Katoh K, Yamazaki R, Onishi A, Sanuki R, Furukawa T, G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells. J Neurosci. 2012 Dec 5;32(49):17658-70
1	J:185536 Lange CA, Luhmann UF, Mowat FM, Georgiadis A, West EL, Abrahams S, Sayed H, Powner MB, Fruttiger M, Smith AJ, Sowden JC, Maxwell PH, Ali RR, Bainbridge JW, Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development. Development. 2012 Jul;139(13):2340-50
1	J:92622 Li S, Mo Z, Yang X, Price SM, Shen MM, Xiang M, Foxn4 controls the genesis of amacrine and horizontal cells by retinal progenitors. Neuron. 2004 Sep 16;43(6):795-807
1	J:207483 Li Y, Hao H, Tzatzalos E, Lin RK, Doh S, Liu LF, Lyu YL, Cai L, Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells. Biol Open. 2014;3(2):172-84
2	J:343468 Li Y, Xiao D, Chen H, Zheng XFS, Xiang M, Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms. iScience. 2023 Dec 15;26(12):108544
1	J:184380 Li YN, Radner S, French MM, Pinzon-Duarte G, Daly GH, Burgeson RE, Koch M, Brunken WJ, The gamma3 chain of laminin is widely but differentially expressed in murine basement membranes: expression and functional studies. Matrix Biol. 2012 Mar;31(2):120-34
1	J:314167 Lim S, Kim YJ, Park S, Choi JH, Sung YH, Nishimori K, Kozmik Z, Lee HW, Kim JW, mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Muller glia. Elife. 2021 Oct 22;10:e70079
1	J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027
1	J:246467 Liu W, Cvekl A, Six3 in a small population of progenitors at E8.5 is required for neuroretinal specification via regulating cell signaling and survival in mice. Dev Biol. 2017 Aug 01;428(1):164-175
1	J:297697 Luft V, Reinhard J, Shibuya M, Fischer KD, Faissner A, The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina. Cell Tissue Res. 2015 Feb;359(2):423-440
1	J:181993 Luo H, Jin K, Xie Z, Qiu F, Li S, Zou M, Cai L, Hozumi K, Shima DT, Xiang M, Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):E553-62
1	J:301112 Maddala R, Gao J, Mathias RT, Lewis TR, Arshavsky VY, Levine A, Backer JM, Bresnick AR, Rao PV, Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract. Sci Rep. 2021 Jan 26;11(1):2203
3*	J:210433 Mandal NA, Tran JT, Saadi A, Rahman AK, Huynh TP, Klein WH, Cho JH, Expression and localization of CERKL in the mammalian retina, its response to light-stress, and relationship with NeuroD1 gene. Exp Eye Res. 2013 Jan;106:24-33
2	J:131387 Martins RA, Zindy F, Donovan S, Zhang J, Pounds S, Wey A, Knoepfler PS, Eisenman RN, Roussel MF, Dyer MA, N-myc coordinates retinal growth with eye size during mouse development. Genes Dev. 2008 Jan 15;22(2):179-93
1*	J:297493 Matos-Rodrigues GE, Tan PB, Rocha-Martins M, Charlier CF, Gomes AL, Cabral-Miranda F, Grigaravicius P, Hofmann TG, Frappart PO, Martins RAP, Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome. Dis Model Mech. 2020 Oct 30;13(10):dmm045807
1	J:321803 Niu F, Han P, Zhang J, She Y, Yang L, Yu J, Zhuang M, Tang K, Shi Y, Yang B, Liu C, Peng B, Ji SJ, The m(6)A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells. Elife. 2022 Feb 18;11:e75827
1	J:282593 Norrie JL, Lupo MS, Xu B, Al Diri I, Valentine M, Putnam D, Griffiths L, Zhang J, Johnson D, Easton J, Shao Y, Honnell V, Frase S, Miller S, Stewart V, Zhou X, Chen X, Dyer MA, Nucleome Dynamics during Retinal Development. Neuron. 2019 Nov 6;104(3):512-528.e11
1	J:206963 Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O, Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41
1	J:308304 Persiconi I, Cosmi F, Guadagno NA, Lupo G, De Stefano ME, Dystrophin Is Required for the Proper Timing in Retinal Histogenesis: A Thorough Investigation on the mdx Mouse Model of Duchenne Muscular Dystrophy. Front Neurosci. 2020;14:760
1	J:130904 Poche RA, Kwan KM, Raven MA, Furuta Y, Reese BE, Behringer RR, Lim1 is essential for the correct laminar positioning of retinal horizontal cells. J Neurosci. 2007 Dec 19;27(51):14099-107
1	J:309713 Rhee KD, Yu J, Zhao CY, Fan G, Yang XJ, Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival. Cell Death Dis. 2012 Nov 22;3:e427
2	J:149456 Rocha SF, Lopes SS, Gossler A, Henrique D, Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity. Dev Biol. 2009 Apr 1;328(1):54-65
1	J:204946 Rodrigues PM, Grigaravicius P, Remus M, Cavalheiro GR, Gomes AL, Martins MR, Frappart L, Reuss D, McKinnon PJ, von Deimling A, Martins RA, Frappart PO, Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye. PLoS One. 2013;8(7):e69209
1*	J:157665 Sanuki R, Omori Y, Koike C, Sato S, Furukawa T, Panky, a novel photoreceptor-specific ankyrin repeat protein, is a transcriptional cofactor that suppresses CRX-regulated photoreceptor genes. FEBS Lett. 2010 Feb 19;584(4):753-8
1	J:179784 Sanuki R, Onishi A, Koike C, Muramatsu R, Watanabe S, Muranishi Y, Irie S, Uneo S, Koyasu T, Matsui R, Cherasse Y, Urade Y, Watanabe D, Kondo M, Yamashita T, Furukawa T, miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression. Nat Neurosci. 2011 Sep;14(9):1125-34
1	J:293722 Sawant OB, Jidigam VK, Fuller RD, Zucaro OF, Kpegba C, Yu M, Peachey NS, Rao S, The circadian clock gene Bmal1 is required to control the timing of retinal neurogenesis and lamination of Muller glia in the mouse retina. FASEB J. 2019 Aug;33(8):8745-8758
2	J:86168 Sharma RK, O'Leary TE, Fields CM, Johnson DA, Development of the outer retina in the mouse. Brain Res Dev Brain Res. 2003 Oct 10;145(1):93-105
1*	J:189955 Star EN, Zhu M, Shi Z, Liu H, Pashmforoush M, Sauve Y, Bruneau BG, Chow RL, Regulation of retinal interneuron subtype identity by the Iroquois homeobox gene Irx6. Development. 2012 Dec;139(24):4644-55
1	J:91136 Tasheva ES, Ke A, Deng Y, Jun C, Takemoto LJ, Koester A, Conrad GW, Differentially expressed genes in the lens of mimecan-null mice. Mol Vis. 2004 Jun 17;10:403-16
2	J:274446 Wei W, Liu B, Jiang H, Jin K, Xiang M, Requirement of the Mowat-Wilson Syndrome Gene Zeb2 in the Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development. Mol Neurobiol. 2019 Mar;56(3):1719-1736
1	J:306055 Weir K, Kim DW, Blackshaw S, A potential role for somatostatin signaling in regulating retinal neurogenesis. Sci Rep. 2021 May 26;11(1):10962
1*	J:274764 Wu KC, Chen XJ, Jin GH, Wang XY, Yang DD, Li YP, Xiang L, Zhang BW, Zhou GH, Zhang CJ, Jin ZB, Deletion of miR-182 Leads to Retinal Dysfunction in Mice. Invest Ophthalmol Vis Sci. 2019 Mar 1;60(4):1265-1274
1	J:307191 Wu M, Deng Q, Lei X, Du Y, Shen Y, Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype. Invest Ophthalmol Vis Sci. 2021 Jun 1;62(7):1
1	J:280461 Xiao D, Jin K, Xiang M, Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development. Front Mol Neurosci. 2018;11:271
1	J:331692 Xin Y, He Q, Liang H, Zhang K, Guo J, Zhong Q, Chen D, Li J, Liu Y, Chen S, m(6)A epitranscriptomic modification regulates neural progenitor-to-glial cell transition in the retina. Elife. 2022 Dec 2;11
2	J:243794 Yan N, Cheng L, Cho K, Malik MT, Xiao L, Guo C, Yu H, Zhu R, Rao RC, Chen DF, Postnatal onset of retinal degeneration by loss of embryonic Ezh2 repression of Six1. Sci Rep. 2016 Sep 28;6:33887
1	J:334713 Zhang J, Roberts JM, Chang F, Schwakopf J, Vetter ML, Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1. Cell Rep. 2023 Mar 28;42(3):112237
1	J:225537 Zhang J, Taylor RJ, La Torre A, Wilken MS, Cox KE, Reh TA, Vetter ML, Ezh2 maintains retinal progenitor proliferation, transcriptional integrity, and the timing of late differentiation. Dev Biol. 2015 Jul 15;403(2):128-38
1	J:241572 Zhang Q, Zagozewski J, Cheng S, Dixit R, Zhang S, de Melo J, Mu X, Klein WH, Brown NL, Wigle JT, Schuurmans C, Eisenstat DD, Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina. Development. 2017 May 01;144(9):1698-1711
2	J:339443 Zocchi L, Mehta A, Wu SC, Wu J, Gu Y, Wang J, Suh S, Spitale RC, Benavente CA, Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression. Oncogenesis. 2020 Feb 18;9(2):25
1	J:217063 Zou M, Luo H, Xiang M, Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Dev Dyn. 2015 Jan;244(1):86-97