Gene Expression Literature Summary

• Symbol: Pdha1
• Name: pyruvate dehydrogenase E1 alpha 1
• ID: MGI:97532

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E3	E3.5	E4	E6.5	E9.5	E10.5	E11.5	E14.5	E15.5	E17.5	E18.5	P
Immunohistochemistry (section)						1		2		1		1
In situ RNA (section)									2		1		1
In situ RNA (whole mount)							1
Northern blot	1												1
Western blot												1	1
RT-PCR		2	1	1	1	2		1		1	1	2	4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pdha1  pyruvate dehydrogenase E1 alpha 1   (Synonyms: Pdha-1)
Results	Reference
1*	J:142334 Blewitt ME, Gendrel AV, Pang Z, Sparrow DB, Whitelaw N, Craig JM, Apedaile A, Hilton DJ, Dunwoodie SL, Brockdorff N, Kay GF, Whitelaw E, SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation. Nat Genet. 2008 May;40(5):663-9
1	J:236179 Bowman CE, Zhao L, Hartung T, Wolfgang MJ, Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series. Mol Cell Biol. 2016 Aug 1;36(15):2089-104
1	J:240028 Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A, Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2	J:222220 Iso T, Maeda K, Hanaoka H, Suga T, Goto K, Syamsunarno MR, Hishiki T, Nagahata Y, Matsui H, Arai M, Yamaguchi A, Abumrad NA, Sano M, Suematsu M, Endo K, Hotamisligil GS, Kurabayashi M, Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle. Arterioscler Thromb Vasc Biol. 2013 Nov;33(11):2549-57
2	J:150959 Kalantry S, Purushothaman S, Bowen RB, Starmer J, Magnuson T, Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation. Nature. 2009 Jul 30;460(7255):647-51
1*	J:344337 Mishra A, Tavasoli M, Sokolenko S, McMaster CR, Pasumarthi KBS, Atrial natriuretic peptide signaling co-regulates lipid metabolism and ventricular conduction system gene expression in the embryonic heart. iScience. 2024 Jan 19;27(1):108748
1	J:185555 Mugford JW, Yee D, Magnuson T, Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation. Development. 2012 Jun;139(12):2130-8
1*	J:149737 Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ, The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511
1*	J:249661 Schatton D, Pla-Martin D, Marx MC, Hansen H, Mourier A, Nemazanyy I, Pessia A, Zentis P, Corona T, Kondylis V, Barth E, Schauss AC, Velagapudi V, Rugarli EI, CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017 Mar 06;216(3):675-693
9*	J:16409 Takakubo F, Dahl HH, Analysis of pyruvate dehydrogenase expression in embryonic mouse brain: localization and developmental regulation. Brain Res Dev Brain Res. 1994 Jan 14;77(1):63-76
2	J:169365 Turner JM, Mahadevaiah SK, Benavente R, Offenberg HH, Heyting C, Burgoyne PS, Analysis of male meiotic 'sex body' proteins during XY female meiosis provides new insights into their functions. Chromosoma. 2000 Sep;109(6):426-32
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2	J:40650 Wang Q, Latham KE, Requirement for protein synthesis during embryonic genome activation in mice. Mol Reprod Dev. 1997 Jul;47(3):265-70
3	J:171449 Williams LH, Kalantry S, Starmer J, Magnuson T, Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass. Development. 2011 May;138(10):2049-57