Gene Expression Literature Summary

• Symbol: Nefl
• Name: neurofilament, light polypeptide
• ID: MGI:97313

141 matching records from 141 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19.5	P
Immunohistochemistry (section)		1		7	2	6	2	9	1	7	2	5	1	5	1	5	5	1	4	10		32
In situ RNA (section)				5	1	2	1	7		7		12		5		3		2	1		1	10
Immunohistochemistry (whole mount)				3		1				2	1	6	1			1				6		8
In situ RNA (whole mount)				2
Northern blot	1		1	1	1		1	1				1	1			1						3
Western blot																1						7
RT-PCR				1				2	1		1	2	2	2	1	1			1			10

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nefl  neurofilament, light polypeptide   (Synonyms: CMT2E, NF68, Nfl, NF-L)
Results	Reference
2	J:119656 Andrieu D, Meziane H, Marly F, Angelats C, Fernandez PA, Muscatelli F, Sensory defects in Necdin deficient mice result from a loss of sensory neurons correlated within an increase of developmental programmed cell death. BMC Dev Biol. 2006;6:56
1	J:310136 Armfield BA, Cohn MJ, Single cell transcriptomic analysis of external genitalia reveals complex and sexually dimorphic cell populations in the early genital tubercle. Dev Biol. 2021 Sep;477:145-154
1*	J:63629 Baas D, Bumsted KM, Martinez JA, Vaccarino FM, Wikler KC, Barnstable CJ, The subcellular localization of OTX2 is cell-type specific and developmentally regulated in the mouse retina. Brain Res Mol Brain Res. 2000 May 31;78(1-2):26-37
1*	J:140337 Balastik M, Ferraguti F, Pires-da Silva A, Lee TH, Alvarez-Bolado G, Lu KP, Gruss P, Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12016-21
2	J:110726 Banks GB, Choy PT, Lavidis NA, Noakes PG, Neuromuscular synapses mediate motor axon branching and motoneuron survival during the embryonic period of programmed cell death. Dev Biol. 2003 May 1;257(1):71-84
1*	J:181601 Bassett EA, Korol A, Deschamps PA, Buettner R, Wallace VA, Williams T, West-Mays JA, Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:200759 Bok J, Zenczak C, Hwang CH, Wu DK, Auditory ganglion source of Sonic hedgehog regulates timing of cell cycle exit and differentiation of mammalian cochlear hair cells. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13869-74
1	J:311855 Brudvig JJ, Cain JT, Schmidt-Grimminger GG, Stumpo DJ, Roux KJ, Blackshear PJ, Weimer JM, MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation. Mol Neurobiol. 2018 Nov;55(11):8388-8402
1	J:92326 Burton Q, Cole LK, Mulheisen M, Chang W, Wu DK, The role of Pax2 in mouse inner ear development. Dev Biol. 2004 Aug 1;272(1):161-75
2	J:171024 Calmont A, Thapar N, Scambler PJ, Burns AJ, Absence of the vagus nerve in the stomach of Tbx1-/- mutant mice. Neurogastroenterol Motil. 2011 Feb;23(2):125-30
3	J:333392 Cao R, Chen P, Wang H, Jing H, Zhang H, Xing G, Luo B, Pan J, Yu Z, Xiong WC, Mei L, Intrafusal-fiber LRP4 for muscle spindle formation and maintenance in adult and aged animals. Nat Commun. 2023 Feb 10;14(1):744
1	J:332132 Cattaneo P, Hayes MGB, Baumgarten N, Hecker D, Peruzzo S, Aslan GS, Kunderfranco P, Larcher V, Zhang L, Contu R, Fonseca G, Spinozzi S, Chen J, Condorelli G, Dimmeler S, Schulz MH, Heinz S, Guimaraes-Camboa N, Evans SM, DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. Nat Commun. 2022 Dec 2;13(1):7444
1*	J:80954 Chapman DL, Papaioannou VE, Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6. Nature. 1998 Feb 12;391(6668):695-7
1	J:138244 Chatzopoulou E, Miguez A, Savvaki M, Levasseur G, Muzerelle A, Muriel MP, Goureau O, Watanabe K, Goutebroze L, Gaspar P, Zalc B, Karagogeos D, Thomas JL, Structural requirement of TAG-1 for retinal ganglion cell axons and myelin in the mouse optic nerve. J Neurosci. 2008 Jul 23;28(30):7624-36
1	J:154602 Chen Y, Wu H, Wang S, Koito H, Li J, Ye F, Hoang J, Escobar SS, Gow A, Arnett HA, Trapp BD, Karandikar NJ, Hsieh J, Lu QR, The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination. Nat Neurosci. 2009 Nov;12(11):1398-406
2	J:51146 Chien CL, Lee TH, Lu KS, Distribution of neuronal intermediate filament proteins in the developing mouse olfactory system. J Neurosci Res. 1998 Nov 1;54(3):353-63
1	J:104329 Choo D, Ward J, Reece A, Dou H, Lin Z, Greinwald J, Molecular mechanisms underlying inner ear patterning defects in kreisler mutants. Dev Biol. 2006 Jan 15;289(2):308-17
1	J:36170 Cifuentes-Diaz C, Goudou D, Padilla F, Facchinetti P, Nicolet M, Mege RM, Rieger F, M-cadherin distribution in the mouse adult neuromuscular system suggests a role in muscle innervation. Eur J Neurosci. 1996 Aug;8(8):1666-76
1	J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4
1*	J:152211 Coulpier F, Le Crom S, Maro GS, Manent J, Giovannini M, Maciorowski Z, Fischer A, Gessler M, Charnay P, Topilko P, Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers. Glia. 2009 Oct;57(13):1450-7
1	J:40384 Craig JC, Eberwine JH, Calvin JA, Wlodarczyk B, Bennett GD, Finnell RH, Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. Biochem Mol Med. 1997 Apr;60(2):81-91
4*	J:22536 Dahlstrand J, Lardelli M, Lendahl U, Nestin mRNA expression correlates with the central nervous system progenitor cell state in many, but not all, regions of developing central nervous system. Brain Res Dev Brain Res. 1995 Jan 14;84(1):109-29
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2	J:345130 Eguchi T, Tezuka T, Watanabe Y, Inoue-Yamauchi A, Sagara H, Ozawa M, Yamanashi Y, Calcium-binding protein 7 expressed in muscle negatively regulates age-related degeneration of neuromuscular junctions in mice. iScience. 2024 Feb 16;27(2):108997
1	J:196080 Elsen GE, Hodge RD, Bedogni F, Daza RA, Nelson BR, Shiba N, Reiner SL, Hevner RF, The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4081-6
4	J:54791 Faussone-Pellegrini MS, Matini P, DeFelici M, The cytoskeleton of the myenteric neurons during murine embryonic life. Anat Embryol (Berl). 1999 May;199(5):459-69
1	J:260112 Filipova D, Henry M, Rotshteyn T, Brunn A, Carstov M, Deckert M, Hescheler J, Sachinidis A, Pfitzer G, Papadopoulos S, Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5. PLoS One. 2018;13(3):e0194428
6	J:164131 Formstone CJ, Moxon C, Murdoch J, Little P, Mason I, Basal enrichment within neuroepithelia suggests novel function(s) for Celsr1 protein. Mol Cell Neurosci. 2010 Jul;44(3):210-22
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
2	J:311153 Gahankari A, Dong C, Bartoletti G, Galazo M, He F, Deregulated Rac1 Activity in Neural Crest Controls Cell Proliferation, Migration and Differentiation During Midbrain Development. Front Cell Dev Biol. 2021;9:704769
1*	J:282756 Ganay T, Boizot A, Burrer R, Chauvin JP, Bomont P, Sensory-motor deficits and neurofilament disorganization in gigaxonin-null mice. Mol Neurodegener. 2011 Apr 12;6:25
3	J:200901 Gilley J, Adalbert R, Yu G, Coleman MP, Rescue of Peripheral and CNS Axon Defects in Mice Lacking NMNAT2. J Neurosci. 2013 Aug 14;33(33):13410-24
1*	J:138147 Gros-Louis F, Kriz J, Kabashi E, McDearmid J, Millecamps S, Urushitani M, Lin L, Dion P, Zhu Q, Drapeau P, Julien JP, Rouleau GA, Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish. Hum Mol Genet. 2008 Sep 1;17(17):2691-702
1*	J:316668 Guo J, Ma YH, Yan Q, Wang L, Zeng YS, Wu JL, Li J, Fig4 expression in the rodent nervous system and its potential role in preventing abnormal lysosomal accumulation. J Neuropathol Exp Neurol. 2012 Jan;71(1):28-39
3	J:101728 Gut P, Huber K, Lohr J, Bruhl B, Oberle S, Treier M, Ernsberger U, Kalcheim C, Unsicker K, Lack of an adrenal cortex in Sf1 mutant mice is compatible with the generation and differentiation of chromaffin cells. Development. 2005 Oct;132(20):4611-9
1	J:31946 Hatton KS, Mahon K, Chin L, Chiu FC, Lee HW, Peng D, Morgenbesser SD, Horner J, DePinho RA, Expression and activity of L-Myc in normal mouse development. Mol Cell Biol. 1996 Apr;16(4):1794-804
3	J:192196 Hicks AN, Lorenzetti D, Gilley J, Lu B, Andersson KE, Miligan C, Overbeek PA, Oppenheim R, Bishop CE, Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo. PLoS One. 2012;7(10):e47869
1	J:160258 Holley M, Rhodes C, Kneebone A, Herde MK, Fleming M, Steel KP, Emx2 and early hair cell development in the mouse inner ear. Dev Biol. 2010 Apr 15;340(2):547-56
5	J:48411 Howard MJ, Gershon MD, Development of LBP110 expression by neural crest-derived enteric precursors: migration and differentiation potential in ls/ls mutant mice. J Neurobiol. 1998 Jun 15;35(4):341-54
1	J:208050 Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP, Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Nat Neurosci. 2014 Feb;17(2):240-7
2	J:79390 Huber K, Bruhl B, Guillemot F, Olson EN, Ernsberger U, Unsicker K, Development of chromaffin cells depends on MASH1 function. Development. 2002 Oct;129(20):4729-38
2*	J:96531 Huber K, Karch N, Ernsberger U, Goridis C, Unsicker K, The role of Phox2B in chromaffin cell development. Dev Biol. 2005 Mar 15;279(2):501-8
2	J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98
2	J:113326 Izmiryan A, Cheraud Y, Khanamiryan L, Leterrier JF, Federici T, Peltekian E, Moura-Neto V, Paulin D, Li Z, Xue ZG, Different expression of synemin isoforms in glia and neurons during nervous system development. Glia. 2006 Aug 15;54(3):204-13
2	J:105970 Jadhav AP, Mason HA, Cepko CL, Notch 1 inhibits photoreceptor production in the developing mammalian retina. Development. 2006 Mar;133(5):913-23
1	J:314108 Jecrois ES, Zheng W, Bornhorst M, Li Y, Treisman DM, Muguyo D, Huynh S, Andrew SF, Wang Y, Jiang J, Pierce BR, Mao H, Krause MK, Friend A, Nadal-Nicolas F, Stasheff SF, Li W, Zong H, Packer RJ, Zhu Y, Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors. Dev Cell. 2021 Oct 25;56(20):2871-2885.e6
3*	J:11960 Julien JP, Meyer D, Flavell D, Hurst J, Grosveld F, Cloning and developmental expression of the murine neurofilament gene family. Brain Res Mol Brain Res. 1986 Dec;387(3):243-50
1	J:156937 Kanadia RN, Cepko CL, Alternative splicing produces high levels of noncoding isoforms of bHLH transcription factors during development. [RETRACTED Genes Dev. 2011 25: 1344]. Genes Dev. 2010 Feb 1;24(3):229-34
2	J:143205 Kanadia RN, Clark VE, Punzo C, Trimarchi JM, Cepko CL, Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons. Development. 2008 Dec;135(23):3923-33
1	J:70131 Khalyfa A, Bourbeau D, Chen E, Petroulakis E, Pan J, Xu S, Wang E, Characterization of elongation factor-1A (eEF1A-1) and eEF1A-2/S1 protein expression in normal and wasted mice. J Biol Chem. 2001 Jun 22;276(25):22915-22
1	J:99244 Kim J, Wu HH, Lander AD, Lyons KM, Matzuk MM, Calof AL, GDF11 controls the timing of progenitor cell competence in developing retina. Science. 2005 Jun 24;308(5730):1927-30
1	J:312458 Kisseleff E, Vigouroux RJ, Hottin C, Lourdel S, Thomas L, Shah P, Chedotal A, Perron M, Swaroop A, Roger JE, Glycogen Synthase Kinase 3 Regulates the Genesis of Displaced Retinal Ganglion Cells3. eNeuro. 2021 Sep-Oct;8(5):ENEURO.0171-21.2021
1	J:67679 Knoll B, Zarbalis K, Wurst W, Drescher U, A role for the EphA family in the topographic targeting of vomeronasal axons. Development. 2001 Mar;128(6):895-906
1	J:51970 Kubota Y, Morita T, Kusakabe M, Sakakura T, Ito K, Spatial and temporal changes in chondroitin sulfate distribution in the sclerotome play an essential role in the formation of migration patterns of mouse neural crest cells. Dev Dyn. 1999 Jan;214(1):55-65
1	J:41229 Lazzaro MA, Albert PR, Julien JP, A novel cdc2-related protein kinase expressed in the nervous system. J Neurochem. 1997 Jul;69(1):348-64
1	J:306873 Li L, Jin J, Yang XJ, Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells. iScience. 2019 Oct 25;20:148-167
1	J:239195 Li R, Wu F, Ruonala R, Sapkota D, Hu Z, Mu X, Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells. PLoS One. 2014;9(3):e92105
1*	J:94557 Liang S, Zhao S, Mu X, Thomas T, Klein WH, Novel retinal genes discovered by mining the mouse embryonic RetinalExpress database. Mol Vis. 2004 Oct 8;10:773-86
1*	J:68159 Lillevali K, Kulla A, Ord T, Comparative expression analysis of the genes encoding polypyrimidine tract binding protein (PTB) and its neural homologue (brPTB) in prenatal and postnatal mouse brain. Mech Dev. 2001 Mar;101(1-2):217-20
1	J:98487 Lin Z, Cantos R, Patente M, Wu DK, Gbx2 is required for the morphogenesis of the mouse inner ear: a downstream candidate of hindbrain signaling. Development. 2005 May;132(10):2309-18
2	J:181885 Liu C, Bakeri H, Li T, Swaroop A, Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma. Hum Mol Genet. 2012 Apr 15;21(8):1848-60
1	J:267913 Liu WA, Chen S, Li Z, Lee CH, Mirzaa G, Dobyns WB, Ross ME, Zhang J, Shi SH, PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia. Genes Dev. 2018 Jun 1;32(11-12):763-780
1	J:242127 Liu Z, Li W, Ma X, Ding N, Spallotta F, Southon E, Tessarollo L, Gaetano C, Mukouyama YS, Thiele CJ, Essential role of the zinc finger transcription factor Casz1 for mammalian cardiac morphogenesis and development. J Biol Chem. 2014 Oct 24;289(43):29801-16
1	J:264943 Manganelli G, Fico A, Masullo U, Pizzolongo F, Cimmino A, Filosa S, Modulation of the pentose phosphate pathway induces endodermal differentiation in embryonic stem cells. PLoS One. 2012;7(1):e29321
1	J:319652 Mao CA, Agca C, Mocko-Strand JA, Wang J, Ullrich-Luter E, Pan P, Wang SW, Arnone MI, Frishman LJ, Klein WH, Substituting mouse transcription factor Pou4f2 with a sea urchin orthologue restores retinal ganglion cell development. Proc Biol Sci. 2016 Mar 16;283(1826):20152978
1	J:194077 Mao CA, Cho JH, Wang J, Gao Z, Pan P, Tsai WW, Frishman LJ, Klein WH, Reprogramming amacrine and photoreceptor progenitors into retinal ganglion cells by replacing Neurod1 with Atoh7. Development. 2013 Feb 1;140(3):541-51
2	J:130570 Mao CA, Kiyama T, Pan P, Furuta Y, Hadjantonakis AK, Klein WH, Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse. Development. 2008 Jan;135(2):271-80
1	J:141248 Mao CA, Wang SW, Pan P, Klein WH, Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5. Development. 2008 Oct;135(20):3379-88
4	J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89
1*	J:49251 Matise MP, Epstein DJ, Park HL, Platt KA, Joyner AL, Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development. 1998 Aug;125(15):2759-70
3	J:221340 Messeant J, Dobbertin A, Girard E, Delers P, Manuel M, Mangione F, Schmitt A, Le Denmat D, Molgo J, Zytnicki D, Schaeffer L, Legay C, Strochlic L, MuSK frizzled-like domain is critical for mammalian neuromuscular junction formation and maintenance. J Neurosci. 2015 Mar 25;35(12):4926-41
4	J:274139 Messeant J, Ezan J, Delers P, Glebov K, Marchiol C, Lager F, Renault G, Tissir F, Montcouquiol M, Sans N, Legay C, Strochlic L, Wnt proteins contribute to neuromuscular junction formation through distinct signaling pathways. Development. 2017 May 1;144(9):1712-1724
1	J:119026 Morcillo J, Martinez-Morales JR, Trousse F, Fermin Y, Sowden JC, Bovolenta P, Proper patterning of the optic fissure requires the sequential activity of BMP7 and SHH. Development. 2006 Aug;133(16):3179-90
1	J:53713 Morsli H, Tuorto F, Choo D, Postiglione MP, Simeone A, Wu DK, Otx1 and Otx2 activities are required for the normal development of the mouse inner ear. Development. 1999 Jun;126(11):2335-43
2*	J:88577 Mu X, Beremand PD, Zhao S, Pershad R, Sun H, Scarpa A, Liang S, Thomas TL, Klein WH, Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina. Development. 2004 Mar;131(6):1197-210
5	J:21480 Narisawa S, Hasegawa H, Watanabe K, Millan JL, Stage-specific expression of alkaline phosphatase during neural development in the mouse. Dev Dyn. 1994 Nov;201(3):227-35
1	J:229930 Nechiporuk T, McGann J, Mullendorff K, Hsieh J, Wurst W, Floss T, Mandel G, The REST remodeling complex protects genomic integrity during embryonic neurogenesis. Elife. 2016;5:e09584
2	J:37005 Noakes PG, Phillips WD, Hanley TA, Sanes JR, Merlie JP, 43K protein and acetylcholine receptors colocalize during the initial stages of neuromuscular synapse formation in vivo. Dev Biol. 1991;155(1):275-80
2	J:110011 Okada K, Inoue A, Okada M, Murata Y, Kakuta S, Jigami T, Kubo S, Shiraishi H, Eguchi K, Motomura M, Akiyama T, Iwakura Y, Higuchi O, Yamanashi Y, The muscle protein Dok-7 is essential for neuromuscular synaptogenesis. Science. 2006 Jun 23;312(5781):1802-5
1	J:288307 Ou MY, Ju XC, Cai YJ, Sun XY, Wang JF, Fu XQ, Sun Q, Luo ZG, Heterogeneous nuclear ribonucleoprotein A3 controls mitotic progression of neural progenitors via interaction with cohesin. Development. 2020 May 15;147(10):dev185132
2	J:88820 Pan J, Ruest LB, Xu S, Wang E, Immuno-characterization of the switch of peptide elongation factors eEF1A-1/EF-1alpha and eEF1A-2/S1 in the central nervous system during mouse development. Brain Res Dev Brain Res. 2004 Mar 22;149(1):1-8
1	J:303303 Pan M, Yin Y, Wang X, Wang Q, Zhang L, Hu H, Wang C, Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation. Autophagy. 2020 Aug 2;:1-16
1	J:168641 Park D, Xiang AP, Mao FF, Zhang L, Di CG, Liu XM, Shao Y, Ma BF, Lee JH, Ha KS, Walton N, Lahn BT, Nestin is required for the proper self-renewal of neural stem cells. Stem Cells. 2010 Dec;28(12):2162-71
1	J:317904 Parmhans N, Sajgo S, Niu J, Luo W, Badea TC, Characterization of retinal ganglion cell, horizontal cell, and amacrine cell types expressing the neurotrophic receptor tyrosine kinase Ret. J Comp Neurol. 2018 Mar 1;526(4):742-766
1	J:225736 Payne S, Burney MJ, McCue K, Popal N, Davidson SM, Anderson RH, Scambler PJ, A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular development. Dev Biol. 2015 Sep 1;405(1):82-95
1	J:310341 Perez-Garcia CG, ErbB4 in Laminated Brain Structures: A Neurodevelopmental Approach to Schizophrenia. Front Cell Neurosci. 2015;9:472
2	J:71188 Pernas-Alonso R, Perrone-Capano C, Volpicelli F, di Porzio U, Regionalized neurofilament accumulation and motoneuron degeneration are linked phenotypes in wobbler neuromuscular disease. Neurobiol Dis. 2001 Aug;8(4):581-9
5*	J:33482 Pernas-Alonso R, Schaffner AE, Perrone-Capano C, Orlando A, Morelli F, Hansen CT, Barker JL, Esposito B, Cacucci F, di Porzio U, Early upregulation of medium neurofilament gene expression in developing spinal cord of the wobbler mouse mutant. Brain Res Mol Brain Res. 1996 Jun;38(2):267-75
2*	J:4754 Phelps DE, Dressler GR, Aberrant expression of Pax-2 in Danforth's short tail (Sd) mice. Dev Biol. 1993 May;157(1):251-8
2	J:72516 Pirvola U, Spencer-Dene B, Xing-Qun L, Kettunen P, Thesleff I, Fritzsch B, Dickson C, Ylikoski J, FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis. J Neurosci. 2000 Aug 15;20(16):6125-34
1	J:160742 Pla P, Hirsch MR, Le Crom S, Reiprich S, Harley VR, Goridis C, Identification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors. Neural Dev. 2008;3:14
1	J:135299 Plachez C, Andrews W, Liapi A, Knoell B, Drescher U, Mankoo B, Zhe L, Mambetisaeva E, Annan A, Bannister L, Parnavelas JG, Richards LJ, Sundaresan V, Robos are required for the correct targeting of retinal ganglion cell axons in the visual pathway of the brain. Mol Cell Neurosci. 2008 Apr;37(4):719-30
1	J:73904 Plump AS, Erskine L, Sabatier C, Brose K, Epstein CJ, Goodman CS, Mason CA, Tessier-Lavigne M, Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system. Neuron. 2002 Jan 17;33(2):219-32
3*	J:3291 Puschel AW, Westerfield M, Dressler GR, Comparative analysis of Pax-2 protein distributions during neurulation in mice and zebrafish. Mech Dev. 1992 Sep;38(3):197-208
1	J:338811 Qu F, Li W, Xu J, Zhang R, Ke J, Ren X, Meng X, Qin L, Zhang J, Lu F, Zhou X, Luo X, Zhang Z, Wang M, Wu G, Pei D, Chen J, Cui G, Suo S, Peng G, Three-dimensional molecular architecture of mouse organogenesis. Nat Commun. 2023 Jul 31;14(1):4599
1	J:156199 Robel S, Mori T, Zoubaa S, Schlegel J, Sirko S, Faissner A, Goebbels S, Dimou L, Gotz M, Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis. Glia. 2009 Nov 15;57(15):1630-47
1	J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425
1	J:97218 Rossel M, Loulier K, Feuillet C, Alonso S, Carroll P, Reelin signaling is necessary for a specific step in the migration of hindbrain efferent neurons. Development. 2005 Mar;132(6):1175-85
2	J:154244 Rudiger R, Binder E, Tsarovina K, Schmidt M, Reiff T, Stubbusch J, Rohrer H, In vivo role for CREB signaling in the noradrenergic differentiation of sympathetic neurons. Mol Cell Neurosci. 2009 Oct;42(2):142-51
1	J:233532 Scekic-Zahirovic J, Sendscheid O, El Oussini H, Jambeau M, Sun Y, Mersmann S, Wagner M, Dieterle S, Sinniger J, Dirrig-Grosch S, Drenner K, Birling MC, Qiu J, Zhou Y, Li H, Fu XD, Rouaux C, Shelkovnikova T, Witting A, Ludolph AC, Kiefer F, Storkebaum E, Lagier-Tourenne C, Dupuis L, Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss. EMBO J. 2016 May 17;35(10):1077-97
2	J:173638 Schmidt M, Huber L, Majdazari A, Schutz G, Williams T, Rohrer H, The transcription factors AP-2beta and AP-2alpha are required for survival of sympathetic progenitors and differentiated sympathetic neurons. Dev Biol. 2011 Jul 1;355(1):89-100
6	J:329261 Sefton EM, Gallardo M, Tobin CE, Collins BC, Colasanto MP, Merrell AJ, Kardon G, Fibroblast-derived Hgf controls recruitment and expansion of muscle during morphogenesis of the mammalian diaphragm. Elife. 2022 Sep 26;11:e74592
1	J:248896 Shah B, Lutter D, Bochenek ML, Kato K, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Adams RH, Puschel AW, C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development. PLoS One. 2016;11(4):e0154174
1	J:241040 Shah B, Lutter D, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Puschel AW, Rap1 GTPases Are Master Regulators of Neural Cell Polarity in the Developing Neocortex. Cereb Cortex. 2017 Feb 01;27(2):1253-1269
1	J:302395 Shah K, King GD, Jiang H, A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells. J Mol Cell Biol. 2020 Jan 22;12(1):4-16
2	J:277434 Shen C, Li L, Zhao K, Bai L, Wang A, Shu X, Xiao Y, Zhang J, Zhang K, Hui T, Chen W, Zhang B, Hsu W, Xiong WC, Mei L, Motoneuron Wnts regulate neuromuscular junction development. Elife. 2018 Aug 16;7:e34625
4*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1	J:121332 Sieber MA, Storm R, Martinez-de-la-Torre M, Muller T, Wende H, Reuter K, Vasyutina E, Birchmeier C, Lbx1 acts as a selector gene in the fate determination of somatosensory and viscerosensory relay neurons in the hindbrain. J Neurosci. 2007 May 2;27(18):4902-9
2	J:164856 Smorodchenko A, Rupprecht A, Sarilova I, Ninnemann O, Brauer AU, Franke K, Schumacher S, Techritz S, Nitsch R, Schuelke M, Pohl EE, Comparative analysis of uncoupling protein 4 distribution in various tissues under physiological conditions and during development. Biochim Biophys Acta. 2009 Oct;1788(10):2309-19
1*	J:30246 Sommer L, Shah N, Rao M, Anderson DJ, The cellular function of MASH1 in autonomic neurogenesis. Neuron. 1995 Dec;15(6):1245-58
1	J:32557 Staecker H, Van De Water TR, Lefebvre PP, Liu W, Moghadassi M, Galinovic-Schwartz V, Malgrange B, Moonen G, NGF, BDNF and NT-3 play unique roles in the in vitro development and patterning of innervation of the mammalian inner ear. Brain Res Dev Brain Res. 1996 Mar 29;92(1):49-60
1	J:143526 Storm R, Cholewa-Waclaw J, Reuter K, Brohl D, Sieber M, Treier M, Muller T, Birchmeier C, The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei. Development. 2009 Jan;136(2):295-305
3	J:201069 Stubbusch J, Narasimhan P, Huber K, Unsicker K, Rohrer H, Ernsberger U, Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev. 2013 Aug 20;8(1):16
1	J:144999 Su H, Trombly MI, Chen J, Wang X, Essential and overlapping functions for mammalian Argonautes in microRNA silencing. Genes Dev. 2009 Feb 1;23(3):304-17
3	J:28346 Taylor LE, Bennett GD, Finnell RH, Altered gene expression in murine branchial arches following in utero exposure to retinoic acid. J Craniofac Genet Dev Biol. 1995 Jan-Mar;15(1):13-25
2	J:224628 Tevosian SG, Jimenez E, Hatch HM, Jiang T, Morse DA, Fox SC, Padua MB, Adrenal Development in Mice Requires GATA4 and GATA6 Transcription Factors. Endocrinology. 2015 Jul;156(7):2503-17
1*	J:62161 Thomas T, Voss AK, Chowdhury K, Gruss P, Querkopf, a MYST family histone acetyltransferase, is required for normal cerebral cortex development. Development. 2000 Jun;127(12):2537-48
1	J:252682 Toutounchian JJ, McCarty JH, Selective expression of eGFP in mouse perivascular astrocytes by modification of the Mlc1 gene using T2A-based ribosome skipping. Genesis. 2017 Oct;55(10)
3*	J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65
1	J:105216 Trokovic N, Trokovic R, Partanen J, Fibroblast growth factor signalling and regional specification of the pharyngeal ectoderm. Int J Dev Biol. 2005;49(7):797-805
1	J:317051 Tushaus J, Muller SA, Shrouder J, Arends M, Simons M, Plesnila N, Blobel CP, Lichtenthaler SF, The pseudoprotease iRhom1 controls ectodomain shedding of membrane proteins in the nervous system. FASEB J. 2021 Nov;35(11):e21962
4	J:30612 Uetsuki T, Takagi K, Sugiura H, Yoshikawa K, Structure and expression of the mouse necdin gene. Identification of a postmitotic neuron-restrictive core promoter. J Biol Chem. 1996 Jan 12;271(2):918-24
1	J:290264 Vagnozzi AN, Garg K, Dewitz C, Moore MT, Cregg JM, Jeannotte L, Zampieri N, Landmesser LT, Philippidou P, Phrenic-specific transcriptional programs shape respiratory motor output. Elife. 2020 Jan 16;9:e52859
2	J:256148 Varadarajan SG, Kong JH, Phan KD, Kao TJ, Panaitof SC, Cardin J, Eltzschig H, Kania A, Novitch BG, Butler SJ, Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord. Neuron. 2017 May 17;94(4):790-799.e3
1	J:167894 Vondran MW, Clinton-Luke P, Honeywell JZ, Dreyfus CF, BDNF+/- mice exhibit deficits in oligodendrocyte lineage cells of the basal forebrain. Glia. 2010 May;58(7):848-56
1	J:73779 Wang SW, Mu X, Bowers WJ, Kim DS, Plas DJ, Crair MC, Federoff HJ, Gan L, Klein WH, Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development. 2002 Jan;129(2):467-77
1	J:235702 Wang Y, Wu Q, Yang P, Wang C, Liu J, Ding W, Liu W, Bai Y, Yang Y, Wang H, Gao S, Wang X, LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain. Nat Commun. 2016;7:10481
1	J:171395 Weaving L, Mihelec M, Storen R, Sosic D, Grigg JR, Tam PP, Jamieson RV, Twist2: role in corneal stromal keratocyte proliferation and corneal thickness. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5561-70
1	J:214811 Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A, Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development. 2014 Sep;141(17):3420-30
1	J:279388 Weiss AC, Bohnenpoll T, Kurz J, Blank P, Airik R, Ludtke TH, Kleppa MJ, Deuper L, Kaiser M, Mamo TM, Costa R, von Hahn T, Trowe MO, Kispert A, Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. J Pathol. 2019 Aug;248(4):452-463
1*	J:82167 White PH, Farkas DR, McFadden EE, Chapman DL, Defective somite patterning in mouse embryos with reduced levels of Tbx6. Development. 2003 Apr;130(8):1681-90
1	J:121250 Whitlon DS, Rutishauser US, NCAM in the organ of Corti of the developing mouse. J Neurocytol. 1990 Dec;19(6):970-7
3	J:60159 Wolpowitz D, Mason TB, Dietrich P, Mendelsohn M, Talmage DA, Role LW, Cysteine-rich domain isoforms of the neuregulin-1 gene are required for maintenance of peripheral synapses. Neuron. 2000 Jan;25(1):79-91
1	J:235644 Wu Y, Wei FY, Kawarada L, Suzuki T, Araki K, Komohara Y, Fujimura A, Kaitsuka T, Takeya M, Oike Y, Suzuki T, Tomizawa K, Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury. PLoS Genet. 2016 Sep;12(9):e1006355
4*	J:16894 Yamagata T, Momoi MY, Yanagisawa M, Kumagai H, Yamakado M, Momoi T, Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos. Brain Res Dev Brain Res. 1994 Feb 18;77(2):163-76
1*	J:256083 Yang T, Moore M, He F, Pten regulates neural crest proliferation and differentiation during mouse craniofacial development. Dev Dyn. 2018 Feb;247(2):304-314
1	J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54
2	J:309104 Zheng MH, Shi M, Pei Z, Gao F, Han H, Ding YQ, The transcription factor RBP-J is essential for retinal cell differentiation and lamination. Mol Brain. 2009 Dec 18;2:38
2	J:343450 Zhou J, Shi Q, Ge YY, He W, Hu X, Xia W, Yan R, Reticulons 1 and 3 are essential for axonal growth and synaptic maintenance associated with intellectual development. Hum Mol Genet. 2023 Aug 7;32(16):2587-2599
2	J:153073 Zhu X, Liu Y, Yin Y, Shao A, Zhang B, Kim S, Zhou J, MSC p43 required for axonal development in motor neurons. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15944-9