Gene Expression Literature Summary

• Symbol: Casp1
• Name: caspase 1
• ID: MGI:96544

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E3.5	E4	E10.5	E11	E12	E13	E13.5	E15	E15.5	E17	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)						1		1			2			1	1				1
Northern blot																		1
Western blot						1								1		1		1	3
RT-PCR	1	1	1	1	1	1		1		1	2	1		1		2	1		3
RNase protection							1		1		1		1						2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Casp1  caspase 1   (Synonyms: Caspase-1, ICE, Il1bc, interleukin 1 beta-converting enzyme)
Results	Reference
3*	J:54598 Araki T, Saruta T, Okano H, Miura M, Caspase activity is required for nephrogenesis in the developing mouse metanephros. Exp Cell Res. 1999 May 1;248(2):423-9
2	J:262187 Cautivo KM, Lizama CO, Tapia PJ, Agarwal AK, Garg A, Horton JD, Cortes VA, AGPAT2 is essential for postnatal development and maintenance of white and brown adipose tissue. Mol Metab. 2016 Jul;5(7):491-505
1	J:291945 De Arcangelis A, Hamade H, Alpy F, Normand S, Bruyere E, Lefebvre O, Mechine-Neuville A, Siebert S, Pfister V, Lepage P, Laquerriere P, Dembele D, Delanoye-Crespin A, Rodius S, Robine S, Kedinger M, Van Seuningen I, Simon-Assmann P, Chamaillard M, Labouesse M, Georges-Labouesse E, Hemidesmosome integrity protects the colon against colitis and colorectal cancer. Gut. 2017 Oct;66(10):1748-1760
4*	J:56116 Exley GE, Tang C, McElhinny AS, Warner CM, Expression of caspase and BCL-2 apoptotic family members in mouse preimplantation embryos. Biol Reprod. 1999 Jul;61(1):231-9
2	J:307825 Fisher AL, Sangkhae V, Balusikova K, Palaskas NJ, Ganz T, Nemeth E, Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy. Nat Commun. 2021 Jun 29;12(1):4026
1	J:285930 Fritsch M, Gunther SD, Schwarzer R, Albert MC, Schorn F, Werthenbach JP, Schiffmann LM, Stair N, Stocks H, Seeger JM, Lamkanfi M, Kronke M, Pasparakis M, Kashkar H, Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis. Nature. 2019 Nov;575(7784):683-687
1*	J:333003 Griewahn L, Muller-Foxworth M, Peintner L, Wissler M, Weiss M, Brauns-Schubert P, Massoumi R, Borner C, Gross O, Yabal M, Charvet C, Maurer U, SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD. Cell Rep. 2023 Jan 31;42(1):111961
3	J:155983 Ikeda T, Kanazawa T, Otsuka S, Ichii O, Hashimoto Y, Kon Y, Expression of caspase family and muscle- and apoptosis-specific genes during skeletal myogenesis in mouse embryo. J Vet Med Sci. 2009 Sep;71(9):1161-8
1	J:50202 Jurisicova A, Latham KE, Casper RF, Casper RF, Varmuza SL, Expression and regulation of genes associated with cell death during murine preimplantation embryo development. Mol Reprod Dev. 1998 Nov;51(3):243-53
1*	J:262835 Ke FFS, Vanyai HK, Cowan AD, Delbridge ARD, Whitehead L, Grabow S, Czabotar PE, Voss AK, Strasser A, Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK. Cell. 2018 May 17;173(5):1217-1230.e17
1	J:74158 Kuechle MK, Predd HM, Fleckman P, Dale BA, Presland RB, Caspase-14, a keratinocyte specific caspase: mRNA splice variants and expression pattern in embryonic and adult mouse. Cell Death Differ. 2001 Aug;8(8):868-70
1	J:154022 Lopez RG, Garcia-Silva S, Moore SJ, Bereshchenko O, Martinez-Cruz AB, Ermakova O, Kurz E, Paramio JM, Nerlov C, C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation. Nat Cell Biol. 2009 Oct;11(10):1181-90
2*	J:252121 McCoy AM, Herington JL, Stouch AN, Mukherjee AB, Lakhdari O, Blackwell TS, Prince LS, IKKbeta Activation in the Fetal Lung Mesenchyme Alters Lung Vascular Development but Not Airway Morphogenesis. Am J Pathol. 2017 Dec;187(12):2635-2644
2	J:285940 Newton K, Wickliffe KE, Maltzman A, Dugger DL, Reja R, Zhang Y, Roose-Girma M, Modrusan Z, Sagolla MS, Webster JD, Dixit VM, Activity of caspase-8 determines plasticity between cell death pathways. Nature. 2019 Nov;575(7784):679-682
3*	J:310899 Ramesova A, Vesela B, Svandova E, Lesot H, Matalova E, Caspase-1 Inhibition Impacts the Formation of Chondrogenic Nodules, and the Expression of Markers Related to Osteogenic Differentiation and Lipid Metabolism. Int J Mol Sci. 2021 Sep 3;22(17)
5*	J:59317 Roth KA, Kuan C, Haydar TF, D'Sa-Eipper C, Shindler KS, Zheng TS, Kuida K, Flavell RA, Rakic P, Epistatic and independent functions of caspase-3 and Bcl-X(L) in developmental programmed cell death. Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):466-71
2	J:316173 Vesela B, Svandova E, Vanden Berghe T, Tucker AS, Vandenabeele P, Matalova E, Non-apoptotic role for caspase-7 in hair follicles and the surrounding tissue. J Mol Histol. 2015 Oct;46(4-5):443-55
1*	J:49788 Warner CM, Exley GE, McElhinny AS, Tang C, Genetic regulation of preimplantation mouse embryo survival. J Exp Zool. 1998 Sep-Oct 1;282(1-2):272-9
1*	J:43079 Yang C, Li SW, Helminen HJ, Khillan JS, Bao Y, Prockop DJ, Apoptosis of chondrocytes in transgenic mice lacking collagen II. Exp Cell Res. 1997 Sep 15;235(2):370-3
2	J:309361 Zhang Y, Huang K, Zhang Y, Han T, Li L, Ruan C, Sun YH, Shi W, Han W, Wu SQ, Song J, Liu J, Han J, A unique death pathway keeps RIPK1 D325A mutant mice in check at embryonic day 10.5. PLoS Biol. 2021 Aug;19(8):e3001304