Gene Expression Literature Summary

• Symbol: Igfbp1
• Name: insulin-like growth factor binding protein 1
• ID: MGI:96436

39 matching records from 39 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E1.5	E2	E2.5	E3	E4	E4.5	E5.5	E7.5	E8.5	E9.5	E10	E10.5	E11.5	E12	E12.5	E13.5	E14	E14.5	E15	E15.5	E16.5	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)			1							1	1	2		1	1		1	3		1	1
In situ RNA (section)												1	1		2	1	1	4		4	1	1	1	1		2	1	1	5
In situ RNA (whole mount)												1								1								1
Northern blot															1		1	1		1							1		2
Western blot																													2
RT-PCR	1	1		1	1	1	1	1	1	1				2			1	3	2	3		1	4		1	2	5	1	17
cDNA clones																													2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Igfbp1  insulin-like growth factor binding protein 1   (Synonyms: IGFBP-1)
Results	Reference
1	J:305792 Ansarullah, Jain C, Far FF, Homberg S, Wissmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenlander L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Muller TD, Meier M, Tschop MH, Coskun U, Lickert H, Inceptor counteracts insulin signalling in beta-cells to control glycaemia. Nature. 2021 Feb;590(7845):326-331
2*	J:74084 Arnold PM, Ma JY, Citron BA, Zoubine MN, Festoff BW, Selective developmental regulation of gene expression for insulin-like growth factor-binding proteins in mouse spinal cord. Spine (Phila Pa 1976). 2000 Jul 15;25(14):1765-70
2	J:278550 Boing M, Brand-Saberi B, Napirei M, Murine transcription factor Math6 is a regulator of placenta development. Sci Rep. 2018 Oct 9;8(1):14997
1*	J:124356 Bondareva AA, Capecchi MR, Iverson SV, Li Y, Lopez NI, Lucas O, Merrill GF, Prigge JR, Siders AM, Wakamiya M, Wallin SL, Schmidt EE, Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome. Free Radic Biol Med. 2007 Sep 15;43(6):911-23
4	J:106102 Carter AM, Nygard K, Mazzuca DM, Han VK, The expression of insulin-like growth factor and insulin-like growth factor binding protein mRNAs in mouse placenta. Placenta. 2006 Feb-Mar;27(2-3):278-90
8*	J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9
1	J:21349 Cerro JA, Grewal A, Wood TL, Pintar JE, Tissue-specific expression of the insulin-like growth factor binding protein (IGFBP) mRNAs in mouse and rat development. Regul Pept. 1993 Oct 20;48(1-2):189-98
5	J:49984 Damario MA, Liu HC, Mele CA, Horenstein MG, Rosenwaks Z, Immunohistochemical analysis of insulin-like growth factor-binding proteins -1, -2, and -3 in implantation sites of the mouse. J Assist Reprod Genet. 1998 Sep;15(8):513-20
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
4	J:3784 Ferguson MW, Sharpe PM, Thomas BL, Beck F, Differential expression of insulin-like growth factors I and II (IGF I and II), mRNA, peptide and binding protein 1 during mouse palate development: comparison with TGF beta peptide distribution. J Anat. 1992 Oct;181(Pt 2):219-38
2*	J:78218 Foucher I, Volovitch M, Frain M, Kim JJ, Souberbielle JC, Gan L, Unterman TG, Prochiantz A, Trembleau A, Hoxa5 overexpression correlates with IGFBP1 upregulation and postnatal dwarfism: evidence for an interaction between Hoxa5 and Forkhead box transcription factors. Development. 2002 Sep;129(17):4065-74
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
3	J:245044 Janssen L, Dupont L, Bekhouche M, Noel A, Leduc C, Voz M, Peers B, Cataldo D, Apte SS, Dubail J, Colige A, ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis. Angiogenesis. 2016 Jan;19(1):53-65
3	J:326523 Kheirollahi V, Khadim A, Kiliaris G, Korfei M, Barroso MM, Alexopoulos I, Vazquez-Armendariz AI, Wygrecka M, Ruppert C, Guenther A, Seeger W, Herold S, El Agha E, Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis. Cells. 2022 Jun 20;11(12)
3	J:135979 Knox K, Baker JC, Genomic evolution of the placenta using co-option and duplication and divergence. Genome Res. 2008 May;18(5):695-705
1	J:106064 Kobielak A, Fuchs E, Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2322-7
2	J:42775 Lindenbergh-Kortleve DJ, Rosato RR, van Neck JW, Nauta J, van Kleffens M, Groffen C, Zwarthoff EC, Drop SL, Gene expression of the insulin-like growth factor system during mouse kidney development. Mol Cell Endocrinol. 1997 Sep 19;132(1-2):81-91
7*	J:39926 Liu HC, He ZY, Tang YX, Mele CA, Veeck LL, Davis O, Rosenwaks Z, Simultaneous detection of multiple gene expression in mouse and human individual preimplantation embryos. Fertil Steril. 1997 Apr;67(4):733-41
3	J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388
2	J:258670 Mahany EB, Han X, Borges BC, da Silveira Cruz-Machado S, Allen SJ, Garcia-Galiano D, Hoenerhoff MJ, Bellefontaine NH, Elias CF, Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome. Endocrinology. 2018 Apr 1;159(4):1718-1733
3	J:171849 Mori M, Kitazume M, Ose R, Kurokawa J, Koga K, Osuga Y, Arai S, Miyazaki T, Death effector domain-containing protein (DEDD) is required for uterine decidualization during early pregnancy in mice. J Clin Invest. 2011 Jan 4;121(1):318-27
2	J:122252 Ning Y, Hoang B, Schuller AG, Cominski TP, Hsu MS, Wood TL, Pintar JE, Delayed mammary gland involution in mice with mutation of the insulin-like growth factor binding protein 5 gene. Endocrinology. 2007 May;148(5):2138-47
3	J:201076 Okano T, Kelley MW, Expression of insulin-like growth factor binding proteins during mouse cochlear development. Dev Dyn. 2013 Oct;242(10):1210-21
7*	J:20162 Schuller AG, Groffen C, van Neck JW, Zwarthoff EC, Drop SL, cDNA cloning and mRNA expression of the six mouse insulin-like growth factor binding proteins. Mol Cell Endocrinol. 1994 Aug;104(1):57-66
4	J:12803 Schuller AG, Zwarthoff EC, Drop SL, Gene expression of the six insulin-like growth factor binding proteins in the mouse conceptus during mid- and late gestation. Endocrinology. 1993 Jun;132(6):2544-50
1	J:118123 Shen J, Liu J, Xie Y, Diwan BA, Waalkes MP, Fetal onset of aberrant gene expression relevant to pulmonary carcinogenesis in lung adenocarcinoma development induced by in utero arsenic exposure. Toxicol Sci. 2007 Feb;95(2):313-20
2*	J:129818 Stefan M, Ji H, Simmons RA, Cummings DE, Ahima RS, Friedman MI, Nicholls RD, Hormonal and metabolic defects in a prader-willi syndrome mouse model with neonatal failure to thrive. Endocrinology. 2005 Oct;146(10):4377-85
1*	J:88742 Stone SJ, Myers HM, Watkins SM, Brown BE, Feingold KR, Elias PM, Farese RV Jr, Lipopenia and skin barrier abnormalities in DGAT2-deficient mice. J Biol Chem. 2004 Mar 19;279(12):11767-76
2	J:138818 Tatarakis A, Margaritis T, Martinez-Jimenez CP, Kouskouti A, Mohan WS 2nd, Haroniti A, Kafetzopoulos D, Tora L, Talianidis I, Dominant and redundant functions of TFIID involved in the regulation of hepatic genes. Mol Cell. 2008 Aug 22;31(4):531-43
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:197621 Ueno M, Fujita Y, Tanaka T, Nakamura Y, Kikuta J, Ishii M, Yamashita T, Layer V cortical neurons require microglial support for survival during postnatal development. Nat Neurosci. 2013 May;16(5):543-51
2	J:138125 Umekawa T, Sugiyama T, Kihira T, Murabayashi N, Zhang L, Nagao K, Kamimoto Y, Ma N, Yodoi J, Sagawa N, Overexpression of thioredoxin-1 reduces oxidative stress in the placenta of transgenic mice and promotes fetal growth via glucose metabolism. Endocrinology. 2008 Aug;149(8):3980-8
6	J:59625 van Kleffens M, Groffen C, Neck JW, Vermeij-Keers C, Drop SL, mRNA and protein localization of the IGF system during mouse embryonic development in areas with apoptosis. Growth Horm IGF Res. 1999 Jun;9(3):195-204
3*	J:48168 van Kleffens M, Groffen C, Rosato RR, van den Eijnde SM, van Neck JW, Lindenbergh-Kortleve DJ, Zwarthoff EC, Drop SL, mRNA expression patterns of the IGF system during mouse limb bud development, determined by whole mount in situ hybridization. Mol Cell Endocrinol. 1998 Mar 16;138(1-2):151-61
2	J:58580 van Kleffens M, Groffen CA, Dits NF, Lindenbergh-Kortleve DJ, Schuller AG, Bradshaw SL, Pintar JE, Zwarthoff EC, Drop SL, van Neck JW, Generation of antisera to mouse insulin-like growth factor binding proteins (IGFBP)-1 to -6: comparison of IGFBP protein and messenger ribonucleic acid localization in the mouse embryo. Endocrinology. 1999 Dec;140(12):5944-52
2	J:25933 Wang E, Wang J, Chin E, Zhou J, Bondy CA, Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis. Endocrinology. 1995 Jun;136(6):2741-51
1	J:201463 Watson LA, Solomon LA, Li JR, Jiang Y, Edwards M, Shin-ya K, Beier F, Berube NG, Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span. J Clin Invest. 2013 May 1;123(5):2049-63
1	J:64338 Wood TL, Rogler LE, Czick ME, Schuller AG, Pintar JE, Selective alterations in organ sizes in mice with a targeted disruption of the insulin-like growth factor binding protein-2 gene. Mol Endocrinol. 2000 Sep;14(9):1472-82
1	J:312465 Yin Y, Haller ME, Chadchan SB, Kommagani R, Ma L, Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization. JCI Insight. 2021 Sep 8;6(17)