Gene Expression Literature Summary

• Symbol: Idh2
• Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
• ID: MGI:96414

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10.5	E13.5	E14.5	E15	E16	E17.5	E18.5	E19.5	P
In situ RNA (section)			3
In situ RNA (whole mount)	1
In situ reporter (knock in)									1
Western blot	1	1				1		1	2
RT-PCR	1	1		1	1	2	1		4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Idh2  isocitrate dehydrogenase 2 (NADP+), mitochondrial   (Synonyms: Idh-2, IDPm)
Results	Reference
8*	J:215544 Bogdanovic E, Sadri AR, Catapano M, Vance JE, Jeschke MG, IDH1 regulates phospholipid metabolism in developing astrocytes. Neurosci Lett. 2014 Oct 17;582:87-92
1*	J:236179 Bowman CE, Zhao L, Hartung T, Wolfgang MJ, Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series. Mol Cell Biol. 2016 Aug 1;36(15):2089-104
1	J:240028 Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A, Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4
1*	J:125993 Cankaya M, Hernandez AM, Ciftci M, Beydemir S, Ozdemir H, Budak H, Gulcin I, Comakli V, Emircupani T, Ekinci D, Kuzu M, Jiang Q, Eichele G, Kufrevioglu OI, An analysis of expression patterns of genes encoding proteins with catalytic activities. BMC Genomics. 2007;8:232
2	J:336417 Chong D, Gu Y, Zhang T, Xu Y, Bu D, Chen Z, Xu N, Li L, Zhu X, Wang H, Li Y, Zheng F, Wang D, Li P, Xu L, Hu Z, Li C, Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming. Cell Discov. 2022 Oct 11;8(1):106
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
1	J:366814 Kasprzyk-Pawelec A, Tan M, Rahhal R, McIntosh A, Fernandez HR, Mosaoa RM, Jiang L, Pearson GW, Glasgow E, Vockley J, Albanese C, Avantaggiati ML, Inactivation of the SLC25A1 gene during embryogenesis induces a unique senescence program controlled by p53. Cell Death Differ. 2025 May;32(5):818-836
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:364201 Shi H, Li J, Li F, Yu H, Zhang F, Wu T, Yang L, Li Y, Hu R, Chen M, Sg N, Zhuang X, Feng S, Zhu L, Duan R, Vitamin C-Dependent Intergenerational Inheritance of Enhanced Endurance Performance Following Maternal Exercise. Adv Sci (Weinh). 2025 Apr;12(13):e2408912
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:363090 Yamamoto T, Maurya SK, Pruzinsky E, Batmanov K, Xiao Y, Sulon SM, Sakamoto T, Wang Y, Lai L, McDaid KS, Shewale SV, Leone TC, Koves TR, Muoio DM, Dierickx P, Lazar MA, Lewandowski ED, Kelly DP, RIP140 deficiency enhances cardiac fuel metabolism and protects mice from heart failure. J Clin Invest. 2023 May 1;133(9)