Gene Expression Literature Summary

• Symbol: Icam1
• Name: intercellular adhesion molecule 1
• ID: MGI:96392

47 matching records from 47 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2.5	E3	E4	E10.5	E11	E11.5	E12	E12.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19.5	E	P
Immunohistochemistry (section)						1	1	2	1	3		3	1	1		4		3	2	4	2	2	15
In situ RNA (section)												1								1
Immunohistochemistry (whole mount)	1	1	1	1	1						1	1			1	1	2	1	1				1
Western blot																			1		1
RT-PCR								2				1								1	2		7

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Icam1  intercellular adhesion molecule 1   (Synonyms: CD54, Icam-1, Ly-47, MALA-2, MGC:6195)
Results	Reference
1	J:159868 Benezech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, Ware CF, Anderson G, Caamano JH, Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010 Apr 15;184(8):4521-30
3*	J:148493 Briot A, Deraison C, Lacroix M, Bonnart C, Robin A, Besson C, Dubus P, Hovnanian A, Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome. J Exp Med. 2009 May 11;206(5):1135-47
2*	J:180855 Briot A, Lacroix M, Robin A, Steinhoff M, Deraison C, Hovnanian A, Par2 inactivation inhibits early production of TSLP, but not cutaneous inflammation, in Netherton syndrome adult mouse model. J Invest Dermatol. 2010 Dec;130(12):2736-42
4*	J:36690 Buck CA, Edelman JM, Buck CE, Kennedy G, Baldwin HS, Expression patterns of adhesion receptors in the developing mouse lung: functional implications. Cell Adhes Commun. 1996 Aug;4(2):69-87
1	J:286704 Cheng HW, Onder L, Novkovic M, Soneson C, Lutge M, Pikor N, Scandella E, Robinson MD, Miyazaki JI, Tersteegen A, Sorg U, Pfeffer K, Rulicke T, Hehlgans T, Ludewig B, Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp. Nat Commun. 2019 Apr 15;10(1):1739
2	J:283927 Choi SY, Bae H, Jeong SH, Park I, Cho H, Hong SP, Lee DH, Lee CK, Park JS, Suh SH, Choi J, Yang MJ, Jang JY, Onder L, Moon JH, Jeong HS, Adams RH, Kim JM, Ludewig B, Song JH, Lim DS, Koh GY, YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells. Nat Commun. 2020 Jan 24;11(1):519
4	J:166533 Daneman R, Zhou L, Kebede AA, Barres BA, Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature. 2010 Nov 25;468(7323):562-6
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:87395 Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR, An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol. 2004 Jan;5(1):64-73
1	J:143564 Francois M, Caprini A, Hosking B, Orsenigo F, Wilhelm D, Browne C, Paavonen K, Karnezis T, Shayan R, Downes M, Davidson T, Tutt D, Cheah KS, Stacker SA, Muscat GE, Achen MG, Dejana E, Koopman P, Sox18 induces development of the lymphatic vasculature in mice. Nature. 2008 Dec 4;456(7222):643-7
1*	J:183953 Francois M, Short K, Secker GA, Combes A, Schwarz Q, Davidson TL, Smyth I, Hong YK, Harvey NL, Koopman P, Segmental territories along the cardinal veins generate lymph sacs via a ballooning mechanism during embryonic lymphangiogenesis in mice. Dev Biol. 2012 Apr 15;364(2):89-98
1	J:139005 Geske MJ, Zhang X, Patel KK, Ornitz DM, Stappenbeck TS, Fgf9 signaling regulates small intestinal elongation and mesenchymal development. Development. 2008 Sep;135(17):2959-68
1	J:22425 Gurtner GC, Davis V, Li H, McCoy MJ, Sharpe A, Cybulsky MI, Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation. Genes Dev. 1995 Jan 1;9(1):1-14
1	J:289854 Haglin S, Berghard A, Bohm S, Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia. J Neurosci. 2020 May 20;40(21):4116-4129
1*	J:64178 Hart A, Melet F, Grossfeld P, Chien K, Jones C, Tunnacliffe A, Favier R, Bernstein A, Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia. Immunity. 2000 Aug;13(2):167-77
1	J:96392 Herron BJ, Rao C, Liu S, Laprade L, Richardson JA, Olivieri E, Semsarian C, Millar SE, Stubbs L, Beier DR, A mutation in NFkB interacting protein 1 results in cardiomyopathy and abnormal skin development in wa3 mice. Hum Mol Genet. 2005 Mar 1;14(5):667-77
2*	J:28133 Heyward SA, Dubois-Stringfellow N, Rapoport R, Bautch VL, Expression and inducibility of vascular adhesion receptors in development. FASEB J. 1995 Jul;9(10):956-62
1*	J:296375 Holmes G, Gonzalez-Reiche AS, Lu N, Zhou X, Rivera J, Kriti D, Sebra R, Williams AA, Donovan MJ, Potter SS, Pinto D, Zhang B, van Bakel H, Jabs EW, Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis. Cell Rep. 2020 Jul 7;32(1):107871
3*	J:67917 Honda K, Nakano H, Yoshida H, Nishikawa S, Rennert P, Ikuta K, Tamechika M, Yamaguchi K, Fukumoto T, Chiba T, Nishikawa SI, Molecular basis for hematopoietic/mesenchymal interaction during initiation of peyer's patch organogenesis. J Exp Med. 2001 Mar 5;193(5):621-30
1	J:277787 Ikuta K, Fukuda A, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Tsuda M, Kimura Y, Matsumoto Y, Kimura Y, Maruno T, Kanda K, Nishi K, Takaori K, Uemoto S, Takaishi S, Chiba T, Nishi E, Seno H, Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice. Gut. 2019 May;68(5):882-892
2*	J:238698 Kasparek P, Ileninova Z, Zbodakova O, Kanchev I, Benada O, Chalupsky K, Brattsand M, Beck IM, Sedlacek R, KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype. PLoS Genet. 2017 Jan;13(1):e1006566
1	J:309103 Katoh H, Shibata S, Fukuda K, Sato M, Satoh E, Nagoshi N, Minematsu T, Matsuzaki Y, Akazawa C, Toyama Y, Nakamura M, Okano H, The dual origin of the peripheral olfactory system: placode and neural crest. Mol Brain. 2011 Sep 23;4:34
1*	J:101334 Kojima N, Shiojiri N, Sakai Y, Miyajima A, Expression of neuritin during liver maturation and regeneration. FEBS Lett. 2005 Aug 29;579(21):4562-6
1	J:283314 Kraut B, Maier HJ, Kokai E, Fiedler K, Boettger T, Illing A, Kostin S, Walther P, Braun T, Wirth T, Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality. PLoS One. 2015;10(11):e0141591
1	J:337772 Liang X, Aranyi T, Zhou J, Guan Y, Hu H, Liu H, Susztak K, Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment. J Am Soc Nephrol. 2023 Apr 1;34(4):572-589
6	J:81855 Lu DP, Tian L, O'Neill C, King NJ, Regulation of cellular adhesion molecule expression in murine oocytes, peri-implantation and post-implantation embryos. Cell Res. 2002 Dec;12(5-6):373-83
1	J:133954 Martinez-Sanz E, Del Rio A, Barrio C, Murillo J, Maldonado E, Garcillan B, Amoros M, Fuerte T, Fernandez A, Trinidad E, Rabadan MA, Lopez Y, Martinez ML, Martinez-Alvarez C, Alteration of medial-edge epithelium cell adhesion in two Tgf-beta3 null mouse strains. Differentiation. 2008 Apr;76(4):417-30
1	J:144402 Miralles F, Hebrard S, Lamotte L, Durel B, Gilgenkrantz H, Li Z, Daegelen D, Tuil D, Joshi RL, Conditional inactivation of the murine serum response factor in the pancreas leads to severe pancreatitis. Lab Invest. 2006 Oct;86(10):1020-36
1	J:162556 Murdoch B, DelConte C, Garcia-Castro MI, Embryonic Pax7-expressing progenitors contribute multiple cell types to the postnatal olfactory epithelium. J Neurosci. 2010 Jul 14;30(28):9523-32
2*	J:78842 Nishioka E, Tanaka T, Yoshida H, Matsumura K, Nishikawa S, Naito A, Inoue J, Funasaka Y, Ichihashi M, Miyasaka M, Nishikawa S, Mucosal addressin cell adhesion molecule 1 plays an unexpected role in the development of mouse guard hair. J Invest Dermatol. 2002 Sep;119(3):632-8
1	J:217542 Obata Y, Kimura S, Nakato G, Iizuka K, Miyagawa Y, Nakamura Y, Furusawa Y, Sugiyama M, Suzuki K, Ebisawa M, Fujimura Y, Yoshida H, Iwanaga T, Hase K, Ohno H, Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues. EMBO Rep. 2014 Dec;15(12):1297-304
4	J:259045 Onder L, Morbe U, Pikor N, Novkovic M, Cheng HW, Hehlgans T, Pfeffer K, Becher B, Waisman A, Rulicke T, Gommerman J, Mueller CG, Sawa S, Scandella E, Ludewig B, Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis. Immunity. 2017 Jul 18;47(1):80-92.e4
1	J:173538 Packard A, Schnittke N, Romano RA, Sinha S, Schwob JE, {Delta}Np63 regulates stem cell dynamics in the Mammalian olfactory epithelium. J Neurosci. 2011 Jun 15;31(24):8748-59
1	J:258494 Poissonnier L, Villain G, Soncin F, Mattot V, miR126-5p repression of ALCAM and SetD5 in endothelial cells regulates leucocyte adhesion and transmigration. Cardiovasc Res. 2014 Jun 1;102(3):436-47
1	J:276877 Qu X, Harmelink C, Baldwin HS, Tie2 regulates endocardial sprouting and myocardial trabeculation. JCI Insight. 2019 May 21;5
1	J:158668 Qu X, Tompkins K, Batts LE, Puri M, Baldwin S, Abnormal embryonic lymphatic vessel development in Tie1 hypomorphic mice. Development. 2010 Apr;137(8):1285-95
1	J:160065 Reijmers RM, Vondenhoff MF, Roozendaal R, Kuil A, Li JP, Spaargaren M, Pals ST, Mebius RE, Impaired lymphoid organ development in mice lacking the heparan sulfate modifying enzyme glucuronyl C5-epimerase. J Immunol. 2010 Apr 1;184(7):3656-64
1	J:327384 Ren W, Ma Z, Wang L, Feng X, Yu H, Yu Y, Lgr5(+) cells are required and dynamically participate in olfactory epithelium regeneration: a revisiting shows Lgr5 expression in multiple cell lineages. Theranostics. 2022;12(13):5631-5644
1	J:308868 Senf K, Karius J, Stumm R, Neuhaus EM, Chemokine signaling is required for homeostatic and injury-induced neurogenesis in the olfactory epithelium. Stem Cells. 2021 May;39(5):617-635
1	J:190893 Siao CJ, Lorentz CU, Kermani P, Marinic T, Carter J, McGrath K, Padow VA, Mark W, Falcone DJ, Cohen-Gould L, Parrish DC, Habecker BA, Nykjaer A, Ellenson LH, Tessarollo L, Hempstead BL, ProNGF, a cytokine induced after myocardial infarction in humans, targets pericytes to promote microvascular damage and activation. J Exp Med. 2012 Nov 19;209(12):2291-305
1	J:199438 Siegenthaler JA, Choe Y, Patterson KP, Hsieh I, Li D, Jaminet SC, Daneman R, Kume T, Huang EJ, Pleasure SJ, Foxc1 is required by pericytes during fetal brain angiogenesis. Biol Open. 2013 Jul 15;2(7):647-59
3	J:167033 Sugiyama Y, Koike T, Shiojiri N, Developmental changes of cell adhesion molecule expression in the fetal mouse liver. Anat Rec (Hoboken). 2010 Oct;293(10):1698-710
2	J:277451 Valente M, Resende TP, Nascimento DS, Burlen-Defranoux O, Soares-da-Silva F, Dupont B, Cumano A, Pinto-do-O P, Mouse HSA+ immature cardiomyocytes persist in the adult heart and expand after ischemic injury. PLoS Biol. 2019 Jun;17(6):e3000335
3	J:137812 Vondenhoff MF, Desanti GE, Cupedo T, Bertrand JY, Cumano A, Kraal G, Mebius RE, Golub R, Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner. J Leukoc Biol. 2008 Jul;84(1):152-61
2	J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45
1	J:64018 Wang CC, Biben C, Robb L, Nassir F, Barnett L, Davidson NO, Koentgen F, Tarlinton D, Harvey RP, Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera. Dev Biol. 2000 Aug 15;224(2):152-67
1	J:55393 Yoshida H, Honda K, Shinkura R, Adachi S, Nishikawa S, Maki K, Ikuta K, Nishikawa SI, IL-7 receptor alpha+ CD3(-) cells in the embryonic intestine induces the organizing center of Peyer's patches. Int Immunol. 1999 May;11(5):643-55