Gene Expression Literature Summary

• Symbol: Hoxc8
• Name: homeobox C8
• ID: MGI:96198

115 matching records from 115 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18.5	E19	E19.5	E20	E	P
Immunohistochemistry (section)					1		6		9		15		4	4			1				1		1		2	1
In situ RNA (section)	2	1	3		2		2		5		23	1	6	4	1	7	1	1		2	3					6
Immunohistochemistry (whole mount)		2	3	1	2	1	2				1
In situ RNA (whole mount)	1	2	7	4	8	1	16	3	10		5		2		1	2									1
In situ reporter (knock in)				1	1						3		1													1
Northern blot				2	1	2	1	1		1	1	1					1					1		1	1	4
Western blot											1			1
RT-PCR	1		5	1	7		3	1	6		1	1	2	4	2	1	1	3	1	1	2		1	1		6
cDNA clones	1		2		2
RNase protection																									1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hoxc8  homeobox C8   (Synonyms: D130011F21Rik, Hox-3.1)
Results	Reference
1*	J:33159 Akasaka T, Kanno M, Balling R, Mieza MA, Taniguchi M, Koseki H, A role for mel-18, a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton. Development. 1996 MAY;122(5):1513-1522
1	J:116889 Andersson O, Reissmann E, Ibanez CF, Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis. EMBO Rep. 2006 Aug;7(8):831-7
4	J:12752 Awgulewitsch A, Bieberich C, Bogarad L, Shashikant C, Ruddle FH, Structural analysis of the Hox-3.1 transcription unit and the Hox-3.2--Hox-3.1 intergenic region. Proc Natl Acad Sci U S A. 1990 Aug;87(16):6428-32
7*	J:32906 Awgulewitsch A, Jacobs D, Differential expression of Hox 3.1 protein in subregions of the embryonic and adult spinal cord. Development. 1990 Mar;108(3):411-20
8*	J:8243 Awgulewitsch A, Utset MF, Hart CP, McGinnis W, Ruddle FH, Spatial restriction in expression of a mouse homoeo box locus within the central nervous system. Nature. 1986 Mar 27-Apr 2;320(6060):328-35
1	J:62547 Barna M, Hawe N, Niswander L, Pandolfi PP, Plzf regulates limb and axial skeletal patterning. Nat Genet. 2000 Jun;25(2):166-72
1*	J:85875 Bayarsaihan D, Bitchevaia N, Enkhmandakh B, Tussie-Luna MI, Leckman JF, Roy A, Ruddle F, Expression of BEN, a member of TFII-I family of transcription factors, during mouse pre- and postimplantation development. Gene Expr Patterns. 2003 Oct;3(5):579-89
1*	J:50401 Bel S, Core N, Djabali M, Kieboom K, Van der Lugt N, Alkema MJ , Van Lohuizen M, Genetic interactions and dosage effects of Polycomb group genes in mice. Development. 1998 Sep;125(18):3543-51
5*	J:46174 Belting HG, Shashikant CS, Ruddle FH, Modification of expression and cis-regulation of hoxc8 in the evolution of diverged axial morphology. Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2355-60
11*	J:49697 Belting HG, Shashikant CS, Ruddle FH, Multiple phases of expression and regulation of mouse Hoxc8 during early embryogenesis. J Exp Zool. 1998 Sep-Oct 1;282(1-2):196-222
2	J:153560 Blackburn J, Rich M, Ghitani N, Liu JP, Generation of conditional Hoxc8 loss-of-function and Hoxc8-->Hoxc9 replacement alleles in mice. Genesis. 2009 Jul 20;47(10):680-687
8	J:9304 Breier G, Dressler GR, Gruss P, Primary structure and developmental expression pattern of Hox 3.1, a member of the murine Hox 3 homeobox gene cluster. EMBO J. 1988 May;7(5):1329-36
3*	J:23135 Burke AC, Nelson CE, Morgan BA, Tabin C, Hox genes and the evolution of vertebrate axial morphology. Development. 1995 Feb;121(2):333-46
5	J:227707 Carroll LS, Capecchi MR, Hoxc8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression and Wnt/beta-catenin signaling. Development. 2015 Dec 1;142(23):4056-67
5	J:322321 Catela C, Chen Y, Weng Y, Wen K, Kratsios P, Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. Elife. 2022 Mar 22;11:e70766
4	J:277959 Catela C, Shin MM, Lee DH, Liu JP, Dasen JS, Hox Proteins Coordinate Motor Neuron Differentiation and Connectivity Programs through Ret/Gfralpha Genes. Cell Rep. 2016 Mar 1;14(8):1901-15
1	J:190166 Chen JA, Wichterle H, Apoptosis of limb innervating motor neurons and erosion of motor pool identity upon lineage specific dicer inactivation. Front Neurosci. 2012;6:69
5*	J:119560 Choi MY, Romer AI, Hu M, Lepourcelet M, Mechoor A, Yesilaltay A, Krieger M, Gray PA, Shivdasani RA, A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development. 2006 Oct;133(20):4119-29
2*	J:168654 Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL, Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92
1*	J:88580 Cordes R, Schuster-Gossler K, Serth K, Gossler A, Specification of vertebral identity is coupled to Notch signalling and the segmentation clock. Development. 2004 Mar;131(6):1221-33
1*	J:38487 Core N, Bel S, Gaunt SJ, Aurrand-Lions M, Pearce J, Fisher A, Djabali M, Altered cellular proliferation and mesoderm patterning in Polycomb-M33-deficient mice. Development. 1997 Feb;124(3):721-9
1*	J:124124 Core N, Caubit X, Metchat A, Boned A, Djabali M, Fasano L, Tshz1 is required for axial skeleton, soft palate and middle ear development in mice. Dev Biol. 2007 Aug 15;308(2):407-20
1	J:40384 Craig JC, Eberwine JH, Calvin JA, Wlodarczyk B, Bennett GD, Finnell RH, Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. Biochem Mol Med. 1997 Apr;60(2):81-91
1	J:139297 Dasen JS, De Camilli A, Wang B, Tucker PW, Jessell TM, Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1. Cell. 2008 Jul 25;134(2):304-16
1	J:99734 de Graaff W, Tomotsune D, Oosterveen T, Takihara Y, Koseki H, Deschamps J, Randomly inserted and targeted Hox/reporter fusions transcriptionally silenced in Polycomb mutants. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13362-7
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:115001 Dorrance AM, Liu S, Yuan W, Becknell B, Arnoczky KJ, Guimond M, Strout MP, Feng L, Nakamura T, Yu L, Rush LJ, Weinstein M, Leone G, Wu L, Ferketich A, Whitman SP, Marcucci G, Caligiuri MA, Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations. J Clin Invest. 2006 Oct;116(10):2707-16
1*	J:31004 Dressler GR, Gruss P, Anterior boundaries of Hox gene expression in mesoderm-derived structures correlate with the linear gene order along the chromosome. Differentiation. 1989 Sep;41(3):193-201
1	J:262472 Edmond M, Hanley O, Philippidou P, Topoisomerase IIbeta Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs. eNeuro. 2017 Nov-Dec;4(6):ENEURO.0404-17.2017
2*	J:11610 Erselius JR, Goulding MD, Gruss P, Structure and expression pattern of the murine Hox-3.2 gene. Development. 1990 Oct;110(2):629-42
1*	J:297683 Fernandez-Guerrero M, Yakushiji-Kaminatsui N, Lopez-Delisle L, Zdral S, Darbellay F, Perez-Gomez R, Bolt CC, Sanchez-Martin MA, Duboule D, Ros MA, Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30509-30519
1*	J:157035 Fisher CL, Lee I, Bloyer S, Bozza S, Chevalier J, Dahl A, Bodner C, Helgason CD, Hess JL, Humphries RK, Brock HW, Additional sex combs-like 1 belongs to the enhancer of trithorax and polycomb group and genetically interacts with Cbx2 in mice. Dev Biol. 2010 Jan 1;337(1):9-15
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
4*	J:32272 Gaunt SJ, Mouse homeobox gene transcripts occupy different but overlapping domains in embryonic germ layers and organs: a comparison of Hox-3.1 and Hox-1.5. Development. 1988 May;103(1):135-44
1*	J:10731 Gaunt SJ, Coletta PL, Pravtcheva D, Sharpe PT, Mouse Hox-3.4: homeobox sequence and embryonic expression patterns compared with other members of the Hox gene network. Development. 1990 Jun;109(2):329-39
1*	J:30750 Gaunt SJ, Sharpe PT, Duboule D, Spatially restricted domains of homeo-gene transcripts in mouse embryos: relation to a segmented body plan. Development. 1988;104(Suppl):169-79
1*	J:32030 Graham A, Maden M, Krumlauf R, The murine Hox-2 genes display dynamic dorsoventral patterns of expression during central nervous system development. Development. 1991 May;112(1):255-64
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
5*	J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60
4*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:253351 Hanley O, Zewdu R, Cohen LJ, Jung H, Lacombe J, Philippidou P, Lee DH, Selleri L, Dasen JS, Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns. Neuron. 2016 Sep 7;91(5):1005-1020
2*	J:58953 Hanson RD, Hess JL, Yu BD, Ernst P, van Lohuizen M, Berns A, van der Lugt NM, Shashikant CS, Ruddle FH, Seto M, Korsmeyer SJ, Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development. Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14372-7
2	J:308865 Higashijima Y, Nagai N, Yamamoto M, Kitazawa T, Kawamura YK, Taguchi A, Nakada N, Nangaku M, Furukawa T, Aburatani H, Kurihara H, Wada Y, Kanki Y, Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster. Commun Biol. 2020 Nov 30;3(1):725
2*	J:290828 Holland PW, Hogan BL, Spatially restricted patterns of expression of the homeobox-containing gene Hox 2.1. during mouse embryogenesis. Development. 1988 Jan;102(1):159-74
1*	J:125425 Howell GR, Shindo M, Murray S, Gridley T, Wilson LA, Schimenti JC, Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations. Genetics. 2007 Feb;175(2):699-707
1	J:112635 Ji SJ, Zhuang B, Falco C, Schneider A, Schuster-Gossler K, Gossler A, Sockanathan S, Mesodermal and neuronal retinoids regulate the induction and maintenance of limb innervating spinal motor neurons. Dev Biol. 2006 Sep 1;297(1):249-61
8*	J:85471 Juan AH, Ruddle FH, Enhancer timing of Hox gene expression: deletion of the endogenous Hoxc8 early enhancer. Development. 2003 Oct;130(20):4823-34
3	J:166088 Jung H, Lacombe J, Mazzoni EO, Liem KF Jr, Grinstein J, Mahony S, Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H, Dasen JS, Global control of motor neuron topography mediated by the repressive actions of a single hox gene. Neuron. 2010 Sep 9;67(5):781-96
1	J:198634 Jurberg AD, Aires R, Varela-Lasheras I, Novoa A, Mallo M, Switching axial progenitors from producing trunk to tail tissues in vertebrate embryos. Dev Cell. 2013 Jun 10;25(5):451-62
1*	J:234970 Kalyani R, Lee JY, Min H, Yoon H, Kim MH, Genes Frequently Coexpressed with Hoxc8 Provide Insight into the Discovery of Target Genes. Mol Cells. 2016 May 31;39(5):395-402
3*	J:22469 Kanzler B, Viallet JP, Le Mouellic H, Boncinelli E, Duboule D, Dhouailly D, Differential expression of two different homeobox gene families during mouse tegument morphogenesis. Int J Dev Biol. 1994 Dec;38(4):633-40
1*	J:121991 Katayama K, Furuno A, Akiyama K, Tsuji T, Kunieda T, Characterization of chromosomal inversion of the mouse hairy ears (Eh) mutation associated with cleft palate. Mamm Genome. 2007 Apr;18(4):246-54
1*	J:2748 Kessel M, Gruss P, Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell. 1991 Oct 4;67(1):89-104
1	J:119650 Kim SY, Paylor SW, Magnuson T, Schumacher A, Juxtaposed Polycomb complexes co-regulate vertebral identity. Development. 2006 Dec;133(24):4957-68
1	J:173414 Kondrashov N, Pusic A, Stumpf CR, Shimizu K, Hsieh AC, Xue S, Ishijima J, Shiroishi T, Barna M, Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. Cell. 2011 Apr 29;145(3):383-97
1	J:338694 Kumar S, Alam SS, Bareke E, Beauchamp MC, Dong Y, Chan W, Majewski J, Jerome-Majewska LA, Sf3b4 regulates chromatin remodeler splicing and Hox expression. Differentiation. 2023 May-Jun;131:59-73
19	J:97489 Kwon Y, Shin J, Park HW, Kim MH, Dynamic expression pattern of Hoxc8 during mouse early embryogenesis. Anat Rec A Discov Mol Cell Evol Biol. 2005 Mar;283(1):187-92
2	J:195163 Lacombe J, Hanley O, Jung H, Philippidou P, Surmeli G, Grinstein J, Dasen JS, Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons. PLoS Genet. 2013 Jan;9(1):e1003184
3	J:244791 Li CJ, Hong T, Tung YT, Yen YP, Hsu HC, Lu YL, Chang M, Nie Q, Chen JA, MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord. Nat Commun. 2017 Mar 24;8:14685
1*	J:58846 Li ZL, Shiota K, Stage-specific homeotic vertebral transformations in mouse fetuses induced by maternal hyperthermia during somitogenesis. Dev Dyn. 1999 Dec;216(4-5):336-48
2	J:137385 Lin W, Zhang Z, Chen CH, Behringer RR, Dent SY, Proper Gcn5 histone acetyltransferase expression is required for normal anteroposterior patterning of the mouse skeleton. Dev Growth Differ. 2008 Jun;50(5):321-30
2	J:119016 Liu JP, The function of growth/differentiation factor 11 (Gdf11) in rostrocaudal patterning of the developing spinal cord. Development. 2006 Aug;133(15):2865-74
2	J:109284 Lorente M, Perez C, Sanchez C, Donohoe M, Shi Y, Vidal M, Homeotic transformations of the axial skeleton of YY1 mutant mice and genetic interaction with the Polycomb group gene Ring1/Ring1A. Mech Dev. 2006 Apr;123(4):312-20
2	J:42706 McGrath KE, Palis J, Expression of homeobox genes, including an insulin promoting factor, in the murine yolk sac at the time of hematopoietic initiation. Mol Reprod Dev. 1997 Oct;48(2):145-53
2	J:55879 McPherron AC, Lawler AM, Lee SJ, Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11. Nat Genet. 1999 Jul;22(3):260-4
1*	J:86684 Medina-Martinez O, Ramirez-Solis R, In vivo mutagenesis of the Hoxb8 hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster. Dev Biol. 2003 Dec 1;264(1):77-90
1	J:249220 Melhuish TA, Taniguchi K, Wotton D, Tgif1 and Tgif2 Regulate Axial Patterning in Mouse. PLoS One. 2016;11(5):e0155837
2	J:256105 Mendelsohn AI, Dasen JS, Jessell TM, Divergent Hox Coding and Evasion of Retinoid Signaling Specifies Motor Neurons Innervating Digit Muscles. Neuron. 2017 Feb 22;93(4):792-805.e4
1*	J:157857 Min H, Lee JY, Bok J, Chung HJ, Kim MH, Proliferating cell nuclear antigen (Pcna) as a direct downstream target gene of Hoxc8. Biochem Biophys Res Commun. 2010 Feb 19;392(4):543-7
6	J:204667 Min H, Lee JY, Kim MH, Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth. Int J Biol Sci. 2013;9(9):960-5
4	J:247259 Naruse C, Shibata S, Tamura M, Kawaguchi T, Abe K, Sugihara K, Kato T, Nishiuchi T, Wakana S, Ikawa M, Asano M, New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice. FASEB J. 2017 Jun;31(6):2252-2266
2*	J:211197 Nishimoto S, Minguillon C, Wood S, Logan MP, A combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity. PLoS Genet. 2014 Mar;10(3):e1004245
1*	J:42018 Oh SP, Li E, The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse. Genes Dev. 1997 Jul 15;11(14):1812-26
1	J:300967 Pajovic S, Siddaway R, Bridge T, Sheth J, Rakopoulos P, Kim B, Ryall S, Agnihotri S, Phillips L, Yu M, Li C, Milos S, Patel P, Srikanthan D, Huang A, Hawkins C, Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer. Nat Commun. 2020 Dec 4;11(1):6216
4*	J:89197 Patterson LT, Potter SS, Atlas of Hox gene expression in the developing kidney. Dev Dyn. 2004 Apr;229(4):771-9
1	J:18886 Pellerin I, Schnabel C, Catron KM, Abate C, Hox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox cluster. Mol Cell Biol. 1994 Jul;14(7):4532-45
3*	J:1503 Peterson RL, Jacobs DF, Awgulewitsch A, Hox-3.6: isolation and characterization of a new murine homeobox gene located in the 5' region of the Hox-3 cluster. Mech Dev. 1992 May;37(3):151-66
1	J:197494 Philippidou P, Walsh CM, Aubin J, Jeannotte L, Dasen JS, Sustained Hox5 gene activity is required for respiratory motor neuron development. Nat Neurosci. 2012 Dec;15(12):1636-44
1	J:144016 Ribes V, Le Roux I, Rhinn M, Schuhbaur B, Dolle P, Early mouse caudal development relies on crosstalk between retinoic acid, Shh and Fgf signalling pathways. Development. 2009 Feb;136(4):665-76
2	J:53495 Rundle CH, Kappen C, Developmental expression of the murine Prl-1 protein tyrosine phosphatase gene. J Exp Zool. 1999 May 1;283(6):612-7
1	J:299569 Sanchez-Gurmaches J, Hung CM, Sparks CA, Tang Y, Li H, Guertin DA, PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors. Cell Metab. 2012 Sep 5;16(3):348-62
1	J:290220 Sato T, Kataoka K, Ito Y, Yokoyama S, Inui M, Mori M, Takahashi S, Akita K, Takada S, Ueno-Kudoh H, Asahara H, Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates. Elife. 2020 May 29;9:e53608
1	J:317827 Sawai A, Pfennig S, Bulajic M, Miller A, Khodadadi-Jamayran A, Mazzoni EO, Dasen JS, PRC1 sustains the integrity of neural fate in the absence of PRC2 function. Elife. 2022 Jan 7;11:e72769
1	J:33051 Schnabel CA, Abate-Shen C, Repression by HoxA7 is mediated by the homeodomain and the modulatory action of its N-terminal-arm residues. Mol Cell Biol. 1996 Jun;16(6):2678-88
1	J:208432 Schwarz D, Varum S, Zemke M, Scholer A, Baggiolini A, Draganova K, Koseki H, Schubeler D, Sommer L, Ezh2 is required for neural crest-derived cartilage and bone formation. Development. 2014 Feb;141(4):867-77
1*	J:30288 Shashikant CS, Bieberich CJ, Belting HG, Wang JC, Borbely MA, Ruddle FH, Regulation of Hoxc-8 during mouse embryonic development: identification and characterization of critical elements involved in early neural tube expression. Development. 1995 Dec;121(12):4339-47
1*	J:35249 Sreenath TL, Pollock RA, Bieberich CJ, Functional specificity of Hoxa-4 in vertebral patterning lies outside of the homeodomain. Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9636-40
1*	J:29755 Subramanian V, Meyer BI, Gruss P, Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes. Cell. 1995 Nov 17;83(4):641-53
2*	J:26535 Suemori H, Takahashi N, Noguchi S, Hoxc-9 mutant mice show anterior transformation of the vertebrae and malformation of the sternum and ribs. Mech Dev. 1995 Jun;51(2-3):265-73
1*	J:43764 Takihara Y, Tomotsune D, Shirai M, Katoh-Fukui Y, Nishii K, Motaleb MA , Nomura M , Tsuchiya R , Fujita Y , Shibata Y , Higashinakagawa T , Shimada K, Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects. Development. 1997 Oct;124(19):3673-82
1	J:28346 Taylor LE, Bennett GD, Finnell RH, Altered gene expression in murine branchial arches following in utero exposure to retinoic acid. J Craniofac Genet Dev Biol. 1995 Jan-Mar;15(1):13-25
3	J:109102 Terranova R, Agherbi H, Boned A, Meresse S, Djabali M, Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll. Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6629-34
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
3*	J:15448 Tiret L, Le Mouellic H, Lallemand Y, Maury M, Brulet P, Altering the spatial determinations in the mouse embryos by manipulating the Hox genes. C R Acad Sci III. 1993 Sep;316(9):1009-24
6*	J:45780 Tiret L, Le Mouellic H, Maury M, Brulet P, Increased apoptosis of motoneurons and altered somatotopic maps in the brachial spinal cord of Hoxc-8-deficient mice. Development. 1998 Jan;125(2):279-91
2*	J:14430 Tomotsune D, Shoji H, Wakamatsu Y, Kondoh H, Takahashi N, A mouse homologue of the Drosophila tumour-suppressor gene l(2)gl controlled by Hox-C8 in vivo. Nature. 1993 Sep 2;365(6441):69-72
1	J:127131 Ueda T, Watanabe-Fukunaga R, Ogawa H, Fukuyama H, Higashi Y, Nagata S, Fukunaga R, Critical role of the p400/mDomino chromatin-remodeling ATPase in embryonic hematopoiesis. Genes Cells. 2007 May;12(5):581-92
3	J:32907 Utset MF, Awgulewitsch A, Ruddle FH, McGinnis W, Region-specific expression of two mouse homeo box genes. Science. 1987 Mar 13;235(4794):1379-82
2*	J:68720 van den Akker E, Fromental-Ramain C, de Graaff W, Le Mouellic H, Brulet P, Chambon P, Deschamps J, Axial skeletal patterning in mice lacking all paralogous group 8 Hox genes. Development. 2001 May;128(10):1911-21
2	J:35539 van der Lugt NM, Alkema M, Berns A, Deschamps J, The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression. Mech Dev. 1996 Aug;58(1-2):153-64
3	J:97213 Vermot J, Schuhbaur B, Mouellic HL, McCaffery P, Garnier JM, Hentsch D, Brulet P, Niederreither K, Chambon P, Dolle P, Roux IL, Retinaldehyde dehydrogenase 2 and Hoxc8 are required in the murine brachial spinal cord for the specification of Lim1+ motoneurons and the correct distribution of Islet1+ motoneurons. Development. 2005 Apr;132(7):1611-21
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2	J:78736 Wang J, Mager J, Schnedier E, Magnuson T, The mouse PcG gene eed is required for Hox gene repression and extraembryonic development. Mamm Genome. 2002 Sep;13(9):493-503
2	J:238549 Warrier S, Nuwayhid S, Sabatino JA, Sugrue KF, Zohn IE, Supt20 is required for development of the axial skeleton. Dev Biol. 2017 Jan 15;421(2):245-257
1*	J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
4	J:33847 Wlodraczyk B, Bennett GD, Calvin JA, Craig JC, Finnell RH, Arsenic-induced alterations in embryonic transcription factor gene expression: implications for abnormal neural development. Dev Genet. 1996;18(4):306-15
2	J:226712 Wong SF, Agarwal V, Mansfield JH, Denans N, Schwartz MG, Prosser HM, Pourquie O, Bartel DP, Tabin CJ, McGlinn E, Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4884-93
1	J:290593 Yen YP, Hsieh WF, Tsai YY, Lu YL, Liau ES, Hsu HC, Chen YC, Liu TC, Chang M, Li J, Lin SP, Hung JH, Chen JA, Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity. Elife. 2018 Oct 12;7:e38080
1	J:207555 Yokoyama A, Ficara F, Murphy MJ, Meisel C, Hatanaka C, Kitabayashi I, Cleary ML, MLL becomes functional through intra-molecular interaction not by proteolytic processing. PLoS One. 2013;8(9):e73649
1	J:183048 Yokoyama A, Ficara F, Murphy MJ, Meisel C, Naresh A, Kitabayashi I, Cleary ML, Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways. J Cell Sci. 2011 Jul 1;124(Pt 13):2208-19
3*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
2*	J:49400 Yueh YG, Gardner DP, Kappen C, Evidence for regulation of cartilage differentiation by the homeobox gene Hoxc-8. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9956-61
1	J:225113 Zhang Y, Liu Z, Medrzycki M, Cao K, Fan Y, Reduction of Hox gene expression by histone H1 depletion. PLoS One. 2012;7(6):e38829
1	J:170604 Zhang Z, O'Rourke JR, McManus MT, Lewandoski M, Harfe BD, Sun X, The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning. Dev Biol. 2011 Mar 15;351(2):254-65
4*	J:187603 Zhu H, Zhao J, Zhou W, Li H, Zhou R, Zhang L, Zhao H, Cao J, Zhu X, Hu H, Ma G, He L, Yao Z, Yao L, Guo X, Ndrg2 regulates vertebral specification in differentiating somites. Dev Biol. 2012 Sep 15;369(2):308-18