Gene Expression Literature Summary

• Symbol: Hmbs
• Name: hydroxymethylbilane synthase
• ID: MGI:96112

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E2.5	E3	E3.5	E8.5	E9.5	E10.5	E12.5	E13.5	E14.5	E15.5	E16	E17.5	E	P
In situ RNA (section)									2
In situ reporter (knock in)							1							1
Northern blot										1	1
RT-PCR	1	1	1	1	2	1	3	1	1	1		1	2	1
cDNA clones	1
RNase protection													1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hmbs  hydroxymethylbilane synthase   (Synonyms: PBGD, porphobilinogen deaminase, Ups, Uros1)
Results	Reference
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:99174 Drissen R, von Lindern M, Kolbus A, Driegen S, Steinlein P, Beug H, Grosveld F, Philipsen S, The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability. Mol Cell Biol. 2005 Jun;25(12):5205-14
3	J:191565 Grote P, Wittler L, Hendrix D, Koch F, Wahrisch S, Beisaw A, Macura K, Blass G, Kellis M, Werber M, Herrmann BG, The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse. Dev Cell. 2013 Jan 28;24(2):206-14
2*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
3	J:157314 Ling KH, Hewitt CA, Beissbarth T, Hyde L, Banerjee K, Cheah PS, Cannon PZ, Hahn CN, Thomas PQ, Smyth GK, Tan SS, Thomas T, Scott HS, Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling. Genome Biol. 2009;10(10):R104
1	J:313967 Mass E, Wachten D, Aschenbrenner AC, Voelzmann A, Hoch M, Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling. Dev Cell. 2014 Mar 31;28(6):711-26
1	J:146843 Nagata M, Ito T, Arimitsu N, Koyama H, Sekimizu K, Transcription arrest relief by S-II/TFIIS during gene expression in erythroblast differentiation. Genes Cells. 2009 Mar;14(3):371-80
1	J:25650 Nuez B, Michalovich D, Bygrave A, Ploemacher R, Grosveld F, Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene. Nature. 1995 May 25;375(6529):316-8
1	J:25651 Perkins AC, Sharpe AH, Orkin SH, Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF. Nature. 1995 May 25;375(6529):318-22
4	J:159743 Saito K, Abe H, Nakazawa M, Irokawa E, Watanabe M, Hosoi Y, Soma M, Kasuga K, Kojima I, Kobayashi M, Cloning of complementary DNAs encoding structurally related homeoproteins from preimplantation mouse embryos: their involvement in the differentiation of embryonic stem cells. Biol Reprod. 2010 Apr;82(4):687-97
2	J:122680 Shimizu R, Trainor CD, Nishikawa K, Kobayashi M, Ohneda K, Yamamoto M, GATA-1 self-association controls erythroid development in vivo. J Biol Chem. 2007 May 25;282(21):15862-71
2*	J:77275 Shivdasani RA, Orkin SH, Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2. Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8690-4
1	J:163685 Siatecka M, Sahr KE, Andersen SG, Mezei M, Bieker JJ, Peters LL, Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15151-6
1*	J:163355 Tallack MR, Whitington T, Yuen WS, Wainwright EN, Keys JR, Gardiner BB, Nourbakhsh E, Cloonan N, Grimmond SM, Bailey TL, Perkins AC, A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells. Genome Res. 2010 Aug;20(8):1052-63
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6