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Gene Expression Literature Summary
Symbol
Name
ID
Ebf1
early B cell factor 1
MGI:95275

153 matching records from 153 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1.5 E2 E2.5 E3 E3.5 E4.5 E9 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19.5 E20 E P
Immunohistochemistry (section) 1 1 5 1 5 8 1 5 10 1 8 3 8 1 1 12
In situ RNA (section) 1 1 1 8 3 10 35 1 19 3 31 15 3 8 7 1 12 2 14
In situ RNA (whole mount) 4 5 1 4 1 1 1 1 1 2
Western blot 1 2
RT-PCR 1 1 1 1 1 1 1 1 1 4 1 1 1 1 7 1 8
cDNA clones 2 1 1 1 1 4
RNase protection 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Ebf1  early B cell factor 1   (Synonyms: O/E-1, Olf1, Olf-1)
Results  Reference
3*J:114758 Alcaraz WA, Gold DA, Raponi E, Gent PM, Concepcion D, Hamilton BA, Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation. Proc Natl Acad Sci U S A. 2006;103(51):19424-19429
1J:273860 Andreu-Cervera A, Anselme I, Karam A, Laclef C, Catala M, Schneider-Maunoury S, The Ciliopathy Gene Ftm/Rpgrip1l Controls Mouse Forebrain Patterning via Region-Specific Modulation of Hedgehog/Gli Signaling. J Neurosci. 2019 Mar 27;39(13):2398-2415
1J:131380 Arlotta P, Molyneaux BJ, Jabaudon D, Yoshida Y, Macklis JD, Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. J Neurosci. 2008 Jan 16;28(3):622-32
1J:328140 Asgarian Z, Oliveira MG, Stryjewska A, Maragkos I, Rubin AN, Magno L, Pachnis V, Ghorbani M, Hiebert SW, Denaxa M, Kessaris N, MTG8 interacts with LHX6 to specify cortical interneuron subtype identity. Nat Commun. 2022 Sep 5;13(1):5217
2*J:266538 Backer S, Lokmane L, Landragin C, Deck M, Garel S, Bloch-Gallego E, Trio GEF mediates RhoA activation downstream of Slit2 and coordinates telencephalic wiring. Development. 2018 Oct 2;145(19):dev153692
2J:112701 Bailey PJ, Klos JM, Andersson E, Karlen M, Kallstrom M, Ponjavic J, Muhr J, Lenhard B, Sandelin A, Ericson J, A global genomic transcriptional code associated with CNS-expressed genes. Exp Cell Res. 2006 Oct 1;312(16):3108-19
3J:63349 Behrens M, Venkatraman G, Gronostajski RM, Reed RR, Margolis FL, NFI in the development of the olfactory neuroepithelium and the regulation of olfactory marker protein gene expression. Eur J Neurosci. 2000 Apr;12(4):1372-84
4J:174731 Bielle F, Marcos-Mondejar P, Keita M, Mailhes C, Verney C, Nguyen Ba-Charvet K, Tessier-Lavigne M, Lopez-Bendito G, Garel S, Slit2 activity in the migration of guidepost neurons shapes thalamic projections during development and evolution. Neuron. 2011 Mar 24;69(6):1085-98
2*J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
2J:272505 Catela C, Correa E, Wen K, Aburas J, Croci L, Consalez GG, Kratsios P, An ancient role for collier/Olf/Ebf (COE)-type transcription factors in axial motor neuron development. Neural Dev. 2019 Jan 18;14(1):2
3*J:75936 Cau E, Casarosa S, Guillemot F, Mash1 and Ngn1 control distinct steps of determination and differentiation in the olfactory sensory neuron lineage. Development. 2002 Apr;129(8):1871-80
1*J:147160 Chambers D, Wilson LJ, Alfonsi F, Hunter E, Saxena U, Blanc E, Lumsden A, Rhombomere-specific analysis reveals the repertoire of genetic cues expressed across the developing hindbrain. Neural Dev. 2009;4:6
1J:145187 Chen B, Kim EH, Xu PX, Initiation of olfactory placode development and neurogenesis is blocked in mice lacking both Six1 and Six4. Dev Biol. 2009 Feb 1;326(1):75-85
2J:286635 Chen SY, Lu KM, Ko HA, Huang TH, Hao JH, Yan YT, Chang SL, Evans SM, Liu FC, Parcellation of the striatal complex into dorsal and ventral districts. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7418-7429
1J:70560 Chen Z, Rebelo S, White F, Malmberg AB, Baba H, Lima D, Woolf CJ, Basbaum AI, Anderson DJ, The paired homeodomain protein drg11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord. Neuron. 2001 Jul 19;31(1):59-73
2J:184876 Chiara F, Badaloni A, Croci L, Yeh ML, Cariboni A, Hoerder-Suabedissen A, Consalez GG, Eickholt B, Shimogori T, Parnavelas JG, Rakic S, Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem. Dev Biol. 2012 May 1;365(1):277-89
1J:141766 Chung WC, Moyle SS, Tsai PS, Fibroblast growth factor 8 signaling through fibroblast growth factor receptor 1 is required for the emergence of gonadotropin-releasing hormone neurons. Endocrinology. 2008 Oct;149(10):4997-5003
2J:121077 Colombo E, Collombat P, Colasante G, Bianchi M, Long J, Mansouri A, Rubenstein JL, Broccoli V, Inactivation of Arx, the murine ortholog of the X-linked lissencephaly with ambiguous genitalia gene, leads to severe disorganization of the ventral telencephalon with impaired neuronal migration and differentiation. J Neurosci. 2007 Apr 25;27(17):4786-98
1J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20
3*J:65298 Corbin JG, Gaiano N, Machold RP, Langston A, Fishell G, The gsh2 homeodomain gene controls multiple aspects of telencephalic development. Development. 2000 Dec;127(23):5007-20
1*J:85473 Corbin JG, Rutlin M, Gaiano N, Fishell G, Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development. 2003 Oct;130(20):4895-906
1*J:152211 Coulpier F, Le Crom S, Maro GS, Manent J, Giovannini M, Maciorowski Z, Fischer A, Gessler M, Charnay P, Topilko P, Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers. Glia. 2009 Oct;57(13):1450-7
3J:110576 Croci L, Chung SH, Masserdotti G, Gianola S, Bizzoca A, Gennarini G, Corradi A, Rossi F, Hawkes R, Consalez GG, A key role for the HLH transcription factor EBF2COE2,O/E-3 in Purkinje neuron migration and cerebellar cortical topography. Development. 2006 Jul;133(14):2719-29
7*J:34596 Davis JA, Reed RR, Role of Olf-1 and Pax-6 transcription factors in neurodevelopment. J Neurosci. 1996 Aug 15;16(16):5082-94
1J:197849 Deck M, Lokmane L, Chauvet S, Mailhes C, Keita M, Niquille M, Yoshida M, Yoshida Y, Lebrand C, Mann F, Grove EA, Garel S, Pathfinding of corticothalamic axons relies on a rendezvous with thalamic projections. Neuron. 2013 Feb 6;77(3):472-84
1*J:74716 DeKoter RP, Lee HJ, Singh H, PU.1 Regulates Expression of the Interleukin-7 Receptor in Lymphoid Progenitors. Immunity. 2002 Feb;16(2):297-309
3J:92064 Ding YQ, Yin J, Kania A, Zhao ZQ, Johnson RL, Chen ZF, Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord. Development. 2004 Aug;131(15):3693-703
1*J:84873 Ding YQ, Yin J, Xu HM, Jacquin MF, Chen ZF, Formation of whisker-related principal sensory nucleus-based lemniscal pathway requires a paired homeodomain transcription factor, Drg11. J Neurosci. 2003 Aug 13;23(19):7246-54
5J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81
1J:317998 Du A, Wu X, Chen H, Bai QR, Han X, Liu B, Zhang X, Ding Z, Shen Q, Zhao C, Foxg1 Directly Represses Dbx1 to Confine the POA and Subsequently Regulate Ventral Telencephalic Patterning. Cereb Cortex. 2019 Dec 17;29(12):4968-4981
1J:333882 Ehrman JM, Merchan-Sala P, Ehrman LA, Chen B, Lim HW, Waclaw RR, Campbell K, Formation of the Mouse Internal Capsule and Cerebral Peduncle: A Pioneering Role for Striatonigral Axons as Revealed in Isl1 Conditional Mutants. J Neurosci. 2022 Apr 20;42(16):3344-3364
1J:201994 Ehrman LA, Mu X, Waclaw RR, Yoshida Y, Vorhees CV, Klein WH, Campbell K, The LIM homeobox gene Isl1 is required for the correct development of the striatonigral pathway in the mouse. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):E4026-35
1J:66507 Erkman L, Yates PA, McLaughlin T, McEvilly RJ, Whisenhunt T, O'Connell SM, Krones AI, Kirby MA, Rapaport DH, Bermingham JR, O'Leary DD, Rosenfeld MG, A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system. Neuron. 2000 Dec;28(3):779-92
1J:292321 Fan X, Waardenberg AJ, Demuth M, Osteil P, Sun JQJ, Loebel DAF, Graham M, Tam PPL, Fossat N, TWIST1 Homodimers and Heterodimers Orchestrate Lineage-Specific Differentiation. Mol Cell Biol. 2020 May 14;40(11)
2J:194843 Ferri A, Favaro R, Beccari L, Bertolini J, Mercurio S, Nieto-Lopez F, Verzeroli C, La Regina F, De Pietri Tonelli D, Ottolenghi S, Bovolenta P, Nicolis SK, Sox2 is required for embryonic development of the ventral telencephalon through the activation of the ventral determinants Nkx2.1 and Shh. Development. 2013 Mar;140(6):1250-61
1J:174118 Fuccillo M, Rutlin M, Fishell G, Removal of Pax6 partially rescues the loss of ventral structures in Shh null mice. Cereb Cortex. 2006 Jul;16 Suppl 1:i96-102
1J:253958 Fujimura N, Kuzelova A, Ebert A, Strnad H, Lachova J, Machon O, Busslinger M, Kozmik Z, Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation. Dev Biol. 2018 Jan 1;433(1):47-60
2*J:138839 Fulp CT, Cho G, Marsh ED, Nasrallah IM, Labosky PA, Golden JA, Identification of Arx transcriptional targets in the developing basal forebrain. Hum Mol Genet. 2008;17(23):3740-60
1*J:65601 Garel S, Garcia-Dominguez M, Charnay P, Control of the migratory pathway of facial branchiomotor neurones. Development. 2000 Dec;127(24):5297-307
2J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94
13*J:43984 Garel S, Marin F, Mattei MG, Vesque C, Vincent A, Charnay P, Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system. Dev Dyn. 1997 Nov;210(3):191-205
2*J:79830 Garel S, Yun K, Grosschedl R, Rubenstein JL, The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34
2J:240473 Geng X, Acosta S, Lagutin O, Gil HJ, Oliver G, Six3 dosage mediates the pathogenesis of holoprosencephaly. Development. 2016 Dec 01;143(23):4462-4473
1J:140315 Geng X, Speirs C, Lagutin O, Inbal A, Liu W, Solnica-Krezel L, Jeong Y, Epstein DJ, Oliver G, Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. Dev Cell. 2008 Aug;15(2):236-47
2J:266955 Gezelius H, Moreno-Juan V, Mezzera C, Thakurela S, Rodriguez-Malmierca LM, Pistolic J, Benes V, Tiwari VK, Lopez-Bendito G, Genetic Labeling of Nuclei-Specific Thalamocortical Neurons Reveals Putative Sensory-Modality Specific Genes. Cereb Cortex. 2017 Nov 1;27(11):5054-5069
3*J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1J:76658 Gross MK, Dottori M, Goulding M, Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord. Neuron. 2002 May 16;34(4):535-49
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
7*J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
1J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849
1J:119019 Gutin G, Fernandes M, Palazzolo L, Paek H, Yu K, Ornitz DM, McConnell SK, Hebert JM, FGF signalling generates ventral telencephalic cells independently of SHH. Development. 2006 Aug;133(15):2937-46
1J:119561 Hirata T, Nakazawa M, Muraoka O, Nakayama R, Suda Y, Hibi M, Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions. Development. 2006 Oct;133(20):3993-4004
1J:161851 Honma Y, Kawano M, Kohsaka S, Ogawa M, Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret. Development. 2010 Jul;137(14):2319-28
2J:184447 Hu J, Huang T, Li T, Guo Z, Cheng L, c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections. J Neurosci. 2012 Apr 18;32(16):5362-73
1J:212111 Hua ZL, Jeon S, Caterina MJ, Nathans J, Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E3005-14
2*J:87698 Ikawa T, Masuda K, Lu M, Minato N, Katsura Y, Kawamoto H, Identification of the earliest prethymic T-cell progenitors in murine fetal blood. Blood. 2004 Jan 15;103(2):530-7
1J:170495 Ikeda K, Kageyama R, Suzuki Y, Kawakami K, Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development. Int J Dev Biol. 2010;54(10):1453-64
1*J:126356 Ikeda K, Ookawara S, Sato S, Ando Z, Kageyama R, Kawakami K, Six1 is essential for early neurogenesis in the development of olfactory epithelium. Dev Biol. 2007 Nov 1;311(1):53-68
13J:164295 Jin K, Jiang H, Mo Z, Xiang M, Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors. J Neurosci. 2010 Sep 8;30(36):11902-16
1J:302827 Jin K, Jiang H, Xiao D, Zou M, Zhu J, Xiang M, Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis. Mol Brain. 2015 May 13;8:28
2*J:309086 Jin S, Kim J, Willert T, Klein-Rodewald T, Garcia-Dominguez M, Mosqueira M, Fink R, Esposito I, Hofbauer LC, Charnay P, Kieslinger M, Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1. Nat Commun. 2014 May 2;5:3793
1J:184011 John A, Brylka H, Wiegreffe C, Simon R, Liu P, Juttner R, Crenshaw EB 3rd, Luyten FP, Jenkins NA, Copeland NG, Birchmeier C, Britsch S, Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development. 2012 May;139(10):1831-41
2J:342551 Kim EE, Shekhar A, Ramachandran J, Khodadadi-Jamayran A, Liu FY, Zhang J, Fishman GI, The transcription factor EBF1 non-cell-autonomously regulates cardiac growth and differentiation. Development. 2023 Nov 1;150(21)
1J:98539 Kimura J, Suda Y, Kurokawa D, Hossain ZM, Nakamura M, Takahashi M, Hara A, Aizawa S, Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium. J Neurosci. 2005 May 25;25(21):5097-108
1*J:311044 Kovach C, Dixit R, Li S, Mattar P, Wilkinson G, Elsen GE, Kurrasch DM, Hevner RF, Schuurmans C, Neurog2 simultaneously activates and represses alternative gene expression programs in the developing neocortex. Cereb Cortex. 2013 Aug;23(8):1884-900
4*J:63183 Kramer PR, Guerrero G, Krishnamurthy R, Mitchell PJ, Wray S, Ectopic expression of luteinizing hormone-releasing hormone and peripherin in the respiratory epithelium of mice lacking transcription factor AP-2alpha. Mech Dev. 2000 Jun;94(1-2):79-94
2J:288306 Kuriki M, Sato F, Arai HN, Sogabe M, Kaneko M, Kiyonari H, Kawakami K, Yoshimoto Y, Shukunami C, Sehara-Fujisawa A, Transient and lineage-restricted requirement of Ebf3 for sternum ossification. Development. 2020 May 12;147(9):dev186239
1J:122567 Lakhina V, Falnikar A, Bhatnagar L, Tole S, Early thalamocortical tract guidance and topographic sorting of thalamic projections requires LIM-homeodomain gene Lhx2. Dev Biol. 2007 Jun 15;306(2):703-13
1J:130851 Lavado A, Lagutin OV, Oliver G, Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon. Development. 2008 Feb;135(3):441-50
2J:321499 Lee DR, Rhodes C, Mitra A, Zhang Y, Maric D, Dale RK, Petros TJ, Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain. Elife. 2022 Feb 17;11:e71864
6J:339532 Li J, Sun L, Peng XL, Yu XM, Qi SJ, Lu ZJ, Han JJ, Shen Q, Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons. PLoS Genet. 2021 Mar;17(3):e1009355
1J:134641 Liao WL, Tsai HC, Wang HF, Chang J, Lu KM, Wu HL, Lee YC, Tsai TF, Takahashi H, Wagner M, Ghyselinck NB, Chambon P, Liu FC, Modular patterning of structure and function of the striatum by retinoid receptor signaling. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6765-70
1J:98392 Liao WL, Tsai HC, Wu CY, Liu FC, Differential expression of RARbeta isoforms in the mouse striatum during development: A gradient of RARbeta2 expression along the rostrocaudal axis. Dev Dyn. 2005 Jun;233(2):584-94
1J:334752 Liu W, Xie H, Liu X, Xu S, Cheng S, Wang Z, Xie T, Zhang ZC, Han J, PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation. Cell Rep. 2023 Mar 28;42(3):112277
3J:199727 Lokmane L, Proville R, Narboux-Neme N, Gyory I, Keita M, Mailhes C, Lena C, Gaspar P, Grosschedl R, Garel S, Sensory map transfer to the neocortex relies on pretarget ordering of thalamic axons. Curr Biol. 2013 May 6;23(9):810-6
1*J:173286 Long JE, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
1*J:173287 Long JE, Swan C, Liang WS, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
2*J:270210 Loo L, Simon JM, Xing L, McCoy ES, Niehaus JK, Guo J, Anton ES, Zylka MJ, Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun. 2019 Jan 11;10(1):134
4J:144312 Lopez-Bendito G, Cautinat A, Sanchez JA, Bielle F, Flames N, Garratt AN, Talmage DA, Role LW, Charnay P, Marin O, Garel S, Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation. Cell. 2006 Apr 7;125(1):127-42
1J:206284 Lu KM, Evans SM, Hirano S, Liu FC, Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E168-77
2J:165487 Magnani D, Hasenpusch-Theil K, Jacobs EC, Campagnoni AT, Price DJ, Theil T, The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence. J Neurosci. 2010 Oct 13;30(41):13883-94
2J:220860 Magnani D, Morle L, Hasenpusch-Theil K, Paschaki M, Jacoby M, Schurmans S, Durand B, Theil T, The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon. Hum Mol Genet. 2015 May 1;24(9):2578-93
1J:287326 Malik N, Dunn KM, Cassels J, Hay J, Estell C, Sansom OJ, Michie AM, mTORC1 activity is essential for erythropoiesis and B cell lineage commitment. Sci Rep. 2019 Nov 15;9(1):16917
1J:210221 Mandai K, Reimert DV, Ginty DD, Linx mediates interaxonal interactions and formation of the internal capsule. Neuron. 2014 Jul 2;83(1):93-103
1J:338454 Marfull-Oromi P, Fleitas C, Zammou B, Rocandio D, Ballester-Lurbe B, Terrado J, Perez-Roger I, Espinet C, Egea J, Genetic ablation of the Rho GTPase Rnd3 triggers developmental defects in internal capsule and the globus pallidus formation. J Neurochem. 2021 Jul;158(2):197-216
1J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577
3J:101735 Mason HA, Rakowiecki SM, Raftopoulou M, Nery S, Huang Y, Gridley T, Fishell G, Notch signaling coordinates the patterning of striatal compartments. Development. 2005 Oct;132(19):4247-58
1J:219894 Mattar P, Ericson J, Blackshaw S, Cayouette M, A conserved regulatory logic controls temporal identity in mouse neural progenitors. Neuron. 2015 Feb 4;85(3):497-504
4*J:241394 Mattiske T, Lee K, Gecz J, Friocourt G, Shoubridge C, Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene. Hum Mol Genet. 2016 Dec 15;25(24):5433-5443
1J:261809 Mayer C, Hafemeister C, Bandler RC, Machold R, Batista Brito R, Jaglin X, Allaway K, Butler A, Fishell G, Satija R, Developmental diversification of cortical inhibitory interneurons. Nature. 2018 Mar 22;555(7697):457-462
8*J:91231 Mella S, Soula C, Morello D, Crozatier M, Vincent A, Expression patterns of the coe/ebf transcription factor genes during chicken and mouse limb development. Gene Expr Patterns. 2004 Sep;4(5):537-42
6*J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
1J:249988 Merchan-Sala P, Nardini D, Waclaw RR, Campbell K, Selective neuronal expression of the SoxE factor, Sox8, in direct pathway striatal projection neurons of the developing mouse brain. J Comp Neurol. 2017 Sep 1;525(13):2805-2819
1J:168181 Metz H, Wray S, Use of mutant mouse lines to investigate origin of gonadotropin-releasing hormone-1 neurons: lineage independent of the adenohypophysis. Endocrinology. 2010 Feb;151(2):766-73
1J:304361 Mitsogiannis MD, Pancho A, Aerts T, Sachse SM, Vanlaer R, Noterdaeme L, Schmucker D, Seuntjens E, Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration. Front Cell Dev Biol. 2020;8:624181
1J:226687 Morello F, Prasad AA, Rehberg K, Vieira de Sa R, Anton-Bolanos N, Leyva-Diaz E, Adolfs Y, Tissir F, Lopez-Bendito G, Pasterkamp RJ, Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development. J Neurosci. 2015 Oct 21;35(42):14205-19
2J:314321 Moruzzo D, Nobbio L, Sterlini B, Consalez GG, Benfenati F, Schenone A, Corradi A, The Transcription Factors EBF1 and EBF2 Are Positive Regulators of Myelination in Schwann Cells. Mol Neurobiol. 2017 Dec;54(10):8117-8127
1*J:88577 Mu X, Beremand PD, Zhao S, Pershad R, Sun H, Scarpa A, Liang S, Thomas TL, Klein WH, Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina. Development. 2004 Mar;131(6):1197-210
2J:86051 Muller M, Jabs N, Lork DE, Fritzsch B, Sander M, Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons. Development. 2003 Dec;130(23):5815-26
4J:78037 Muzio L, DiBenedetto B, Stoykova A, Boncinelli E, Gruss P, Mallamaci A, Conversion of cerebral cortex into basal ganglia in Emx2(-/-) Pax6(Sey/Sey) double-mutant mice. Nat Neurosci. 2002 Aug;5(8):737-45
1J:242687 Nandi S, Gutin G, Blackwood CA, Kamatkar NG, Lee KW, Fishell G, Wang F, Goldfarb M, Hebert JM, FGF-Dependent, Context-Driven Role for FRS Adapters in the Early Telencephalon. J Neurosci. 2017 Jun 07;37(23):5690-5698
2J:65651 Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H, Herrmann BG, Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Mech Dev. 2000 Nov;98(1-2):77-94
1J:80416 Nery S, Fishell G, Corbin JG, The caudal ganglionic eminence is a source of distinct cortical and subcortical cell populations. Nat Neurosci. 2002 Dec;5(12):1279-87
1J:99297 Ohsawa R, Ohtsuka T, Kageyama R, Mash1 and Math3 are required for development of branchiomotor neurons and maintenance of neural progenitors. J Neurosci. 2005 Jun 22;25(25):5857-65
1J:134978 Pan L, Deng M, Xie X, Gan L, ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells. Development. 2008 Jun;135(11):1981-90
1J:96926 Pan L, Yang Z, Feng L, Gan L, Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis. Development. 2005 Feb;132(4):703-12
1*J:60832 Pattyn A, Hirsch M, Goridis C, Brunet JF, Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b. Development. 2000 Apr;127(7):1349-58
1*J:220524 Pehrson JR, Changolkar LN, Costanzi C, Leu NA, Mice without macroH2A histone variants. Mol Cell Biol. 2014 Dec;34(24):4523-33
1J:135403 Rajaii F, Bitzer ZT, Xu Q, Sockanathan S, Expression of the dominant negative retinoid receptor, RAR403, alters telencephalic progenitor proliferation, survival, and cell fate specification. Dev Biol. 2008 Apr 15;316(2):371-82
2J:198125 Rajakumari S, Wu J, Ishibashi J, Lim HW, Giang AH, Won KJ, Reed RR, Seale P, EBF2 determines and maintains brown adipocyte identity. Cell Metab. 2013 Apr 2;17(4):562-74
1*J:226683 Rataj-Baniowska M, Niewiadomska-Cimicka A, Paschaki M, Szyszka-Niagolov M, Carramolino L, Torres M, Dolle P, Krezel W, Retinoic Acid Receptor beta Controls Development of Striatonigral Projection Neurons through FGF-Dependent and Meis1-Dependent Mechanisms. J Neurosci. 2015 Oct 28;35(43):14467-75
2J:112880 Sakhinia E, Byers R, Bashein A, Hoyland J, Buckle AM, Brady G, Gene expression analysis of myeloid and lymphoid lineage markers during mouse haematopoiesis. Br J Haematol. 2006 Oct;135(1):105-16
1J:266826 Sandberg M, Flandin P, Silberberg S, Su-Feher L, Price JD, Hu JS, Kim C, Visel A, Nord AS, Rubenstein JLR, Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons. Neuron. 2016 Sep 21;91(6):1260-1275
2J:242516 Sessa A, Ciabatti E, Drechsel D, Massimino L, Colasante G, Giannelli S, Satoh T, Akira S, Guillemot F, Broccoli V, The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways. Cereb Cortex. 2017 Jun 01;27(6):3378-3396
1J:328873 Shang Z, Yang L, Wang Z, Tian Y, Gao Y, Su Z, Guo R, Li W, Liu G, Li X, Yang Z, Li Z, Zhang Z, The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity. Front Cell Dev Biol. 2022;10:948331
3*J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
1J:228291 Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, Kawasaki H, Ohta K, Tanaka H, Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex. Nat Commun. 2015;6:10232
1*J:160241 Sohn P, Cox M, Chen D, Serra R, Molecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc. BMC Dev Biol. 2010;10:29
1J:243893 Solanki A, Lau CI, Saldana JI, Ross S, Crompton T, The transcription factor Gli3 promotes B cell development in fetal liver through repression of Shh. J Exp Med. 2017 Jul 03;214(7):2041-2058
4J:290119 Soleilhavoup C, Travaglio M, Patrick K, Garcao P, Boobalan E, Adolfs Y, Spriggs RV, Moles-Garcia E, Dhiraj D, Oosterveen T, Ferri SL, Abel T, Brodkin ES, Pasterkamp RJ, Brooks BP, Panman L, Nolz1 expression is required in dopaminergic axon guidance and striatal innervation. Nat Commun. 2020 Jun 19;11(1):3111
1J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035
1*J:70745 Suda Y, Hossain ZM, Kobayashi C, Hatano O, Yoshida M, Matsuo I, Aizawa S, Emx2 directs the development of diencephalon in cooperation with Otx2. Development. 2001 Jul;128(13):2433-50
1J:238410 Sun C, Berry WL, Olson LE, PDGFRalpha controls the balance of stromal and adipogenic cells during adipose tissue organogenesis. Development. 2017 Jan 01;144(1):83-94
1*J:92054 Taglialatela P, Soria JM, Caironi V, Moiana A, Bertuzzi S, Compromised generation of GABAergic interneurons in the brains of Vax1-/- mice. Development. 2004 Sep;131(17):4239-49
5*J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
5J:255379 Tinterri A, Deck M, Keita M, Mailhes C, Rubin AN, Kessaris N, Lokmane L, Bielle F, Garel S, Tangential migration of corridor guidepost neurons contributes to anxiety circuits. J Comp Neurol. 2018 Feb 15;526(3):397-411
2J:268306 Tinterri A, Menardy F, Diana MA, Lokmane L, Keita M, Coulpier F, Lemoine S, Mailhes C, Mathieu B, Merchan-Sala P, Campbell K, Gyory I, Grosschedl R, Popa D, Garel S, Active intermixing of indirect and direct neurons builds the striatal mosaic. Nat Commun. 2018 Nov 9;9(1):4725
3*J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65
1J:232769 Tuncdemir SN, Fishell G, Batista-Brito R, miRNAs are Essential for the Survival and Maturation of Cortical Interneurons. Cereb Cortex. 2015 Jul;25(7):1842-57
1J:127418 Uemura M, Nakao S, Suzuki ST, Takeichi M, Hirano S, OL-Protocadherin is essential for growth of striatal axons and thalamocortical projections. Nat Neurosci. 2007 Sep;10(9):1151-9
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2*J:251629 Waclaw RR, Ehrman LA, Merchan-Sala P, Kohli V, Nardini D, Campbell K, Foxo1 is a downstream effector of Isl1 in direct pathway striatal projection neuron development within the embryonic mouse telencephalon. Mol Cell Neurosci. 2017 Apr;80:44-51
1J:196218 Wang B, Long JE, Flandin P, Pla R, Waclaw RR, Campbell K, Rubenstein JL, Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants. J Comp Neurol. 2013 May 1;521(7):1561-84
1J:78453 Wang SS, Betz AG, Reed RR, Cloning of a Novel Olf-1/EBF-like Gene, O/E-4, by Degenerate Oligo-based Direct Selection. Mol Cell Neurosci. 2002 Jul;20(3):404-14
1J:88585 Wang SS, Lewcock JW, Feinstein P, Mombaerts P, Reed RR, Genetic disruptions of O/E2 and O/E3 genes reveal involvement in olfactory receptor neuron projection. Development. 2004 Mar;131(6):1377-88
5J:40480 Wang SS, Tsai RYL, Reed RR, The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development. J Neurosci. 1997 Jun 1;17(11):4149-58
1J:345358 Wang X, Llamas J, Trecek T, Shi T, Tao L, Makmura W, Crump JG, Segil N, Gnedeva K, SoxC transcription factors shape the epigenetic landscape to establish competence for sensory differentiation in the mammalian organ of Corti. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2301301120
1J:297623 Wang YZ, Fan H, Ji Y, Reynolds K, Gu R, Gan Q, Yamagami T, Zhao T, Hamad S, Bizen N, Takebayashi H, Chen Y, Wu S, Pleasure D, Lam K, Zhou CJ, Olig2 regulates terminal differentiation and maturation of peripheral olfactory sensory neurons. Cell Mol Life Sci. 2020 Sep;77(18):3597-3609
1J:186829 Watanabe K, Tamamaki N, Furuta T, Ackerman SL, Ikenaka K, Ono K, Dorsally derived netrin 1 provides an inhibitory cue and elaborates the 'waiting period' for primary sensory axons in the developing spinal cord. Development. 2006 Apr;133(7):1379-87
1*J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
1J:164254 Xiang C, Zhang KH, Yin J, Arends JJ, Erzurumlu RS, Jacquin MF, Chen ZF, The transcription factor, Lmx1b, is necessary for the development of the principal trigeminal nucleus-based lemniscal pathway. Mol Cell Neurosci. 2010 Aug;44(4):394-403
5*J:107704 Xiang M, Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors. Dev Biol. 1998 May 15;197(2):155-69
2J:35877 Xiang M, Gan L, Zhou L, Klein WH, Nathans J, Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11950-5
2J:280461 Xiao D, Jin K, Xiang M, Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development. Front Mol Neurosci. 2018;11:271
1J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456
1J:242450 Yang Q, Liu S, Yin M, Yin Y, Zhou G, Zhou J, Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse. Dev Neurobiol. 2015 Nov;75(11):1282-94
2*J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
3J:319845 Yu H, Rubinstein M, Low MJ, Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes. Elife. 2022 Jan 19;11:e72883
3J:153550 Yu W, Wang Y, McDonnell K, Stephen D, Bai CB, Patterning of ventral telencephalon requires positive function of Gli transcription factors. Dev Biol. 2009 Oct 1;334(1):264-75
1J:313945 Yuan Y, Loh YE, Han X, Feng J, Ho TV, He J, Jing J, Groff K, Wu A, Chai Y, Spatiotemporal cellular movement and fate decisions during first pharyngeal arch morphogenesis. Sci Adv. 2020 Dec;6(51)
8J:195329 Zee T, Boller S, Gyory I, Makinistoglu MP, Tuckermann JP, Grosschedl R, Karsenty G, The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner. FEBS Lett. 2013 Mar 18;587(6):711-6
3J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44
3J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055

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