Gene Expression Literature Summary

• Symbol: Cyp19a1
• Name: cytochrome P450, family 19, subfamily a, polypeptide 1
• ID: MGI:88587

33 matching records from 33 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2.5	E3.5	E7	E10.5	E11	E11.5	E12.5	E13.5	E14.5	E15	E15.5	E16.5	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)													1							4
In situ RNA (section)								2		1	1		2					1		4
Immunohistochemistry (whole mount)				1
In situ reporter (knock in)																				2
RT-PCR	2	2	1	2	1	2	1	3	4	3	2	1	4	3	3	3	2	4	3	18
cDNA clones																				1
RNase protection																				1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cyp19a1  cytochrome P450, family 19, subfamily a, polypeptide 1   (Synonyms: Ar, ArKO, aromatase, Cyp19, Int5, Int-5, p450arom)
Results	Reference
9*	J:43805 Abe-Dohmae S, Takagi Y, Harada N, Autonomous expression of aromatase during development of mouse brain is modulated by neurotransmitters. J Steroid Biochem Mol Biol. 1997 Apr;61(3-6):299-306
5*	J:83483 Choudhary D, Jansson I, Schenkman JB, Sarfarazi M, Stoilov I, Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues. Arch Biochem Biophys. 2003 Jun 1;414(1):91-100
1*	J:228826 Cisternas CD, Tome K, Caeiro XE, Dadam FM, Garcia-Segura LM, Cambiasso MJ, Sex chromosome complement determines sex differences in aromatase expression and regulation in the stria terminalis and anterior amygdala of the developing mouse brain. Mol Cell Endocrinol. 2015 Oct 15;414:99-110
1	J:71679 Freiman RN, Albright SR, Zheng S, Sha WC, Hammer RE, Tjian R, Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development. Science. 2001 Sep 14;293(5537):2084-7
1	J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36
3	J:3104 Harada N, Yamada K, Ontogeny of aromatase messenger ribonucleic acid in mouse brain: fluorometrical quantitation by polymerase chain reaction. Endocrinology. 1992 Nov;131(5):2306-12
1*	J:100239 Hinshelwood MM, Shelton JM, Richardson JA, Mendelson CR, Temporal and spatial expression of liver receptor homologue-1 (LRH-1) during embryogenesis suggests a potential role in gonadal development. Dev Dyn. 2005 Sep;234(1):159-68
3	J:31756 Honda S, Harada N, Takagi Y, The alternative exons 1 of the mouse aromatase cytochrome P-450 gene. Biochim Biophys Acta. 1996 Mar 1;1305(3):145-50
2*	J:63372 Ivanova T, Beyer C, Ontogenetic expression and sex differences of aromatase and estrogen receptor-alpha/beta mRNA in the mouse hippocampus. Cell Tissue Res. 2000 May;300(2):231-7
1	J:336923 Jiang X, Cheng Y, Zhu Y, Xu C, Li Q, Xing X, Li W, Zou J, Meng L, Azhar M, Cao Y, Tong X, Qin W, Zhu X, Bao J, Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice. Nat Commun. 2023 Jun 22;14(1):3729
2	J:225140 Kanaya M, Tsuda MC, Sagoshi S, Nagata K, Morimoto C, Thu CK, Toda K, Kato S, Ogawa S, Tsukahara S, Regional difference in sex steroid action on formation of morphological sex differences in the anteroventral periventricular nucleus and principal nucleus of the bed nucleus of the stria terminalis. PLoS One. 2014;9(11):e112616
3*	J:47810 Karolczak M, Kuppers E, Beyer C, Developmental expression and regulation of aromatase- and 5alpha-reductase type I mRNA in the male and female mouse hypothalamus. J Neuroendocrinol. 1998 Apr;10(4):267-74
3	J:227782 Komada M, Takahashi M, Ikeda Y, Involvement of SF-1 in neurogenesis and neuronal migration in the developing neocortex. Neurosci Lett. 2015 Jul 23;600:85-90
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
3*	J:51551 Kuppers E, Beyer C, Expression of aromatase in the embryonic and postnatal mouse striatum. Brain Res Mol Brain Res. 1998 Dec 10;63(1):184-8
1	J:173711 Kyronlahti A, Vetter M, Euler R, Bielinska M, Jay PY, Anttonen M, Heikinheimo M, Wilson DB, GATA4 deficiency impairs ovarian function in adult mice. Biol Reprod. 2011 May;84(5):1033-44
8*	J:21125 Lee CH, Taketo T, Normal onset, but prolonged expression, of Sry gene in the B6.YDOM sex-reversed mouse gonad. Dev Biol. 1994 Oct;165(2):442-52
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
5*	J:112870 Mager J, Schultz RM, Brunk BP, Bartolomei MS, Identification of candidate maternal-effect genes through comparison of multiple microarray data sets. Mamm Genome. 2006 Sep;17(9):941-9
3	J:51557 Miner JH, Cunningham J, Sanes JR, Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain. J Cell Biol. 1998 Dec 14;143(6):1713-23
1	J:281436 Nicol B, Grimm SA, Chalmel F, Lecluze E, Pannetier M, Pailhoux E, Dupin-De-Beyssat E, Guiguen Y, Capel B, Yao HH, RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2. Nat Commun. 2019 Nov 11;10(1):5116
1	J:300503 Nicol B, Rodriguez K, Yao HH, Aberrant and constitutive expression of FOXL2 impairs ovarian development and functions in mice. Biol Reprod. 2020 Oct 29;103(5):966-977
3*	J:68689 Patsoula E, Loutradis D, Drakakis P, Kallianidis K, Bletsa R, Michalas S, Expression of mRNA for the LH and FSH receptors in mouse oocytes and preimplantation embryos. Reproduction. 2001 Mar;121(3):455-61
1	J:327192 Rossitto M, Dejardin S, Rands CM, Le Gras S, Migale R, Rafiee MR, Neirijnck Y, Pruvost A, Nguyen AL, Bossis G, Cammas F, Le Gallic L, Wilhelm D, Lovell-Badge R, Boizet-Bonhoure B, Nef S, Poulat F, TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway. Nat Commun. 2022 Jul 29;13(1):4412
1	J:118123 Shen J, Liu J, Xie Y, Diwan BA, Waalkes MP, Fetal onset of aberrant gene expression relevant to pulmonary carcinogenesis in lung adenocarcinoma development induced by in utero arsenic exposure. Toxicol Sci. 2007 Feb;95(2):313-20
4*	J:32243 Stromstedt M, Keeney DS, Waterman MR, Paria BC, Conley AJ, Dey SK, Preimplantation mouse blastocysts fail to express CYP genes required for estrogen biosynthesis. Mol Reprod Dev. 1996 Apr;43(4):428-36
1	J:226885 Tannour-Louet M, Han S, Louet JF, Zhang B, Romero K, Addai J, Sahin A, Cheung SW, Lamb DJ, Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action. Nat Med. 2014 Jul;20(7):715-24
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*	J:57530 Toyooka Y, Tanaka SS, Hirota O, Tanaka S, Takagi N, Yamanouchi K, Tojo H, Tachi C, Wilms' tumor suppressor gene (WT1) as a target gene of SRY function in a mouse ES cell line transfected with SRY. Int J Dev Biol. 1998 Nov;42(8):1143-51
2*	J:220075 Unger EK, Burke KJ Jr, Yang CF, Bender KJ, Fuller PM, Shah NM, Medial amygdalar aromatase neurons regulate aggression in both sexes. Cell Rep. 2015 Feb 3;10(4):453-62
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
4*	J:333014 Wartenberg P, Farkas I, Csillag V, Colledge WH, Hrabovszky E, Boehm U, Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain. J Neurosci. 2021 Nov 3;41(44):9177-9191
1*	J:220472 Zhao L, Svingen T, Ng ET, Koopman P, Female-to-male sex reversal in mice caused by transgenic overexpression of Dmrt1. Development. 2015 Mar 15;142(6):1083-8