Gene Expression Literature Summary

• Symbol: Cpa1
• Name: carboxypeptidase A1, pancreatic
• ID: MGI:88478

96 matching records from 96 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E8.5	E10	E10.5	E11	E11.5	E12	E12.5	E13.5	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19.5	E	P
Immunohistochemistry (section)				2		8	2	18	20	24	1	23	1	4	1	3	1	8	1	2	13
In situ RNA (section)								1		4		1
Immunohistochemistry (whole mount)										1
Northern blot													1								1
Western blot																		1			6
RT-PCR	1	1	1	4	1	2		4	2	2		5				2		2			6

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cpa1  carboxypeptidase A1, pancreatic   (Synonyms: 0910001L12Rik)
Results	Reference
1*	J:175542 Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Sussel L, The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration. Development. 2011 Aug;138(15):3213-24
2	J:57072 Apelqvist A, Li H, Sommer L, Beatus P, Anderson DJ, Honjo T, Hrabe de Angelis M, Lendahl U, Edlund H, Notch signalling controls pancreatic cell differentiation. Nature. 1999 Aug 26;400(6747):877-81
1*	J:231585 Arnes L, Akerman I, Balderes DA, Ferrer J, Sussel L, betalinc1 encodes a long noncoding RNA that regulates islet beta-cell formation and function. Genes Dev. 2016 Mar 1;30(5):502-7
1	J:240765 Arregi I, Climent M, Iliev D, Strasser J, Gouignard N, Johansson JK, Singh T, Mazur M, Semb H, Artner I, Minichiello L, Pera EM, Retinol Dehydrogenase-10 Regulates Pancreas Organogenesis and Endocrine Cell Differentiation via Paracrine Retinoic Acid Signaling. Endocrinology. 2016 Dec;157(12):4615-4631
3	J:336187 Barlow HR, Ahuja N, Bierschenk T, Htike Y, Fassetta L, Azizoglu DB, Flores J, Gao N, De la O S, Sneddon JB, Marciano DK, Cleaver O, Rab11 is essential to pancreas morphogenesis, lumen formation and endocrine mass. Dev Biol. 2023 Jul;499:59-74
3	J:213751 Baumgartner BK, Cash G, Hansen H, Ostler S, Murtaugh LC, Distinct requirements for beta-catenin in pancreatic epithelial growth and patterning. Dev Biol. 2014 Jul 1;391(1):89-98
1*	J:177580 Begum S, Papaioannou VE, Dynamic expression of Tbx2 and Tbx3 in developing mouse pancreas. Gene Expr Patterns. 2011 Dec;11(8):476-83
2*	J:73072 Bhushan A, Itoh N, Kato S, Thiery JP, Czernichow P, Bellusci S, Scharfmann R, Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development. 2001 Dec;128(24):5109-17
1	J:146087 Bonal C, Thorel F, Ait-Lounis A, Reith W, Trumpp A, Herrera PL, Pancreatic inactivation of c-Myc decreases acinar mass and transdifferentiates acinar cells into adipocytes in mice. Gastroenterology. 2009 Jan;136(1):309-319.e9
1	J:239317 Bourke LM, Del Monte-Nieto G, Outhwaite JE, Bharti V, Pollock PM, Simmons DG, Adam A, Hur SS, Maghzal GJ, Whitelaw E, Stocker R, Suter CM, Harvey RP, Harten SK, Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse. Differentiation. 2017 Mar - Apr;94:8-20
1	J:279716 Braitsch CM, Azizoglu DB, Htike Y, Barlow HR, Schnell U, Chaney CP, Carroll TJ, Stanger BZ, Cleaver O, LATS1/2 suppress NFkappaB and aberrant EMT initiation to permit pancreatic progenitor differentiation. PLoS Biol. 2019 Jul;17(7):e3000382
4	J:284608 Campbell SA, McDonald CL, Krentz NAJ, Lynn FC, Hoffman BG, TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation. Cell Rep. 2019 Aug 13;28(7):1830-1844.e6
1	J:192746 Carrasco M, Delgado I, Soria B, Martin F, Rojas A, GATA4 and GATA6 control mouse pancreas organogenesis. J Clin Invest. 2012 Oct 1;122(10):3504-15
4	J:337474 Cobo I, Paliwal S, Bodas C, Felipe I, Melia-Aloma J, Torres A, Martinez-Villarreal J, Malumbres M, Garcia F, Millan I, Del Pozo N, Park JC, MacDonald RJ, Munoz J, Mendez R, Real FX, NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation. Nat Commun. 2023 Jun 23;14(1):3761
1	J:269131 Cortijo C, Gouzi M, Tissir F, Grapin-Botton A, Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis. Cell Rep. 2012 Dec 27;2(6):1593-606
2*	J:286215 De Angelis MT, Russo F, D'Angelo F, Federico A, Gemei M, Del Vecchio L, Ceccarelli M, De Felice M, Falco G, Novel pancreas organogenesis markers refine the pancreatic differentiation roadmap of embryonic stem cells. Stem Cell Rev Rep. 2014 Apr;10(2):269-79
1	J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82
1*	J:111160 Di Giacomo G, Koss M, Capellini TD, Brendolan A, Popperl H, Selleri L, Spatio-temporal expression of Pbx3 during mouse organogenesis. Gene Expr Patterns. 2006 Oct;6(7):747-757
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:239144 Direnzo D, Hess DA, Damsz B, Hallett JE, Marshall B, Goswami C, Liu Y, Deering T, Macdonald RJ, Konieczny SF, Induced Mist1 expression promotes remodeling of mouse pancreatic acinar cells. Gastroenterology. 2012 Aug;143(2):469-80
1	J:143476 Gao N, Lelay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH, Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev. 2008 Dec 15;22(24):3435-48
2	J:255620 Gao T, Zhou D, Yang C, Singh T, Penzo-Mendez A, Maddipati R, Tzatsos A, Bardeesy N, Avruch J, Stanger BZ, Hippo signaling regulates differentiation and maintenance in the exocrine pancreas. Gastroenterology. 2013 Jun;144(7):1543-53, 1553.e1
1	J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28
1	J:116542 Georgia S, Bhushan A, p27 Regulates the transition of beta-cells from quiescence to proliferation. Diabetes. 2006 Nov;55(11):2950-6
1*	J:31478 Gittes GK, Galante PE, Hanahan D, Rutter WJ, Debase HT, Lineage-specific morphogenesis in the developing pancreas: role of mesenchymal factors. Development. 1996 Feb;122(2):439-47
3*	J:181023 Gittes GK, Rutter WJ, Onset of cell-specific gene expression in the developing mouse pancreas. Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):1128-32
1*	J:84902 Hald J, Hjorth JP, German MS, Madsen OD, Serup P, Jensen J, Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development. Dev Biol. 2003 Aug 15;260(2):426-37
9	J:214089 Hale MA, Swift GH, Hoang CQ, Deering TG, Masui T, Lee YK, Xue J, MacDonald RJ, The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis. Development. 2014 Aug;141(16):3123-33
1	J:65293 Hebrok M, Kim SK, St Jacques B, McMahon AP, Melton DA, Regulation of pancreas development by hedgehog signaling. Development. 2000 Nov;127(22):4905-13
2	J:307816 Heymans C, Delcorte O, Spourquet C, Villacorte-Tabelin M, Dupasquier S, Achouri Y, Mahibullah S, Lemoine P, Balda MS, Matter K, Pierreux CE, Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function. Sci Rep. 2021 Jul 15;11(1):14519
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
2	J:184814 Horn S, Kobberup S, Jorgensen MC, Kalisz M, Klein T, Kageyama R, Gegg M, Lickert H, Lindner J, Magnuson MA, Kong YY, Serup P, Ahnfelt-Ronne J, Jensen JN, Mind bomb 1 is required for pancreatic beta-cell formation. Proc Natl Acad Sci U S A. 2012 May 8;109(19):7356-61
4	J:174762 Hornblad A, Eriksson AU, Sock E, Hill RE, Ahlgren U, Impaired spleen formation perturbs morphogenesis of the gastric lobe of the pancreas. PLoS One. 2011;6(6):e21753
1	J:277787 Ikuta K, Fukuda A, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Tsuda M, Kimura Y, Matsumoto Y, Kimura Y, Maruno T, Kanda K, Nishi K, Takaori K, Uemoto S, Takaishi S, Chiba T, Nishi E, Seno H, Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice. Gut. 2019 May;68(5):882-892
2	J:163480 Johansson JK, Voss U, Kesavan G, Kostetskii I, Wierup N, Radice GL, Semb H, N-cadherin is dispensable for pancreas development but required for beta-cell granule turnover. Genesis. 2010 Jun;48(6):374-81
1*	J:90459 Johnson CL, Kowalik AS, Rajakumar N, Pin CL, Mist1 is necessary for the establishment of granule organization in serous exocrine cells of the gastrointestinal tract. Mech Dev. 2004 Mar;121(3):261-72
1	J:154990 Kang HS, Kim YS, ZeRuth G, Beak JY, Gerrish K, Kilic G, Sosa-Pineda B, Jensen J, Foley J, Jetten AM, Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol. 2009 Dec;29(24):6366-79
2	J:157396 Kesavan G, Sand FW, Greiner TU, Johansson JK, Kobberup S, Wu X, Brakebusch C, Semb H, Cdc42-mediated tubulogenesis controls cell specification. Cell. 2009 Nov 13;139(4):791-801
1	J:63870 Kim SK, Hebrok M, Li E, Oh SP, Schrewe H, Harmon EB, Lee JS, Melton DA, Activin receptor patterning of foregut organogenesis. Genes Dev. 2000 Aug 1;14(15):1866-71
1	J:75811 Kim SK, Selleri L, Lee JS, Zhang AY, Gu X, Jacobs Y, Cleary ML, Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus. Nat Genet. 2002 Apr;30(4):430-5
5	J:51571 Krapp A, Knofler M, Ledermann B, Burki K, Berney C, Zoerkler N, Hagenbuchle O, Wellauer PK, The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes Dev. 1998 Dec 1;12(23):3752-63
1*	J:187631 Kredo-Russo S, Mandelbaum AD, Ness A, Alon I, Lennox KA, Behlke MA, Hornstein E, Pancreas-enriched miRNA refines endocrine cell differentiation. Development. 2012 Aug;139(16):3021-31
3	J:257923 Krentz NAJ, van Hoof D, Li Z, Watanabe A, Tang M, Nian C, German MS, Lynn FC, Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors. Dev Cell. 2017 Apr 24;41(2):129-142.e6
1*	J:182781 Landsman L, Nijagal A, Whitchurch TJ, Vanderlaan RL, Zimmer WE, Mackenzie TC, Hebrok M, Pancreatic mesenchyme regulates epithelial organogenesis throughout development. PLoS Biol. 2011 Sep;9(9):e1001143
1	J:239872 Larsen BM, Hrycaj SM, Newman M, Li Y, Wellik DM, Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation. Development. 2015 Nov 15;142(22):3859-68
2	J:220325 Lemaire LA, Goulley J, Kim YH, Carat S, Jacquemin P, Rougemont J, Constam DB, Grapin-Botton A, Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis. Development. 2015 Mar 1;142(5):858-70
3	J:73278 Li H, Edlund H, Persistent expression of hlxb9 in the pancreatic epithelium impairs pancreatic development. Dev Biol. 2001 Dec 1;240(1):247-53
2	J:346058 Lu P, Xu J, Shen X, Sun J, Liu M, Niu N, Wang Q, Xue J, Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis. Cell Rep. 2024 Feb 27;43(2):113703
1	J:178160 Ma F, Haumaitre C, Chen F, Han Z, Comparison of murine embryonic pancreatic development in vitro and in vivo. Pancreas. 2011 Oct;40(7):1012-7
2	J:178171 Magenheim J, Klein AM, Stanger BZ, Ashery-Padan R, Sosa-Pineda B, Gu G, Dor Y, Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium. Dev Biol. 2011 Nov 1;359(1):26-36
2	J:267771 Mamidi A, Prawiro C, Seymour PA, de Lichtenberg KH, Jackson A, Serup P, Semb H, Mechanosignalling via integrins directs fate decisions of pancreatic progenitors. Nature. 2018 Dec;564(7734):114-118
1	J:152848 Martinez-Romero C, Rooman I, Skoudy A, Guerra C, Molero X, Gonzalez A, Iglesias M, Lobato T, Bosch A, Barbacid M, Real FX, Hernandez-Munoz I, The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma. J Pathol. 2009 Oct;219(2):205-13
4	J:229014 Marty-Santos L, Cleaver O, Pdx1 regulates pancreas tubulogenesis and E-cadherin expression. Development. 2016 Jan 1;143(1):101-12
1	J:178173 Mastracci TL, Wilcox CL, Arnes L, Panea C, Golden JA, May CL, Sussel L, Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Dev Biol. 2011 Nov 1;359(1):1-11
1	J:125691 Masui T, Long Q, Beres TM, Magnuson MA, Macdonald RJ, Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. Genes Dev. 2007 Oct 15;21(20):2629-43
5*	J:42706 McGrath KE, Palis J, Expression of homeobox genes, including an insulin promoting factor, in the murine yolk sac at the time of hematopoietic initiation. Mol Reprod Dev. 1997 Oct;48(2):145-53
1	J:254493 Munoz-Bravo JL, Flores-Martinez A, Herrero-Martin G, Puri S, Taketo MM, Rojas A, Hebrok M, Cano DA, Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity. PLoS One. 2016;11(10):e0164714
2	J:199284 Munoz-Bravo JL, Hidalgo-Figueroa M, Pascual A, Lopez-Barneo J, Leal-Cerro A, Cano DA, GDNF is required for neural colonization of the pancreas. Development. 2013 Sep;140(17):3669-79
1	J:102698 Murtaugh LC, Law AC, Dor Y, Melton DA, Beta-catenin is essential for pancreatic acinar but not islet development. Development. 2005 Nov;132(21):4663-74
1	J:139250 Nakhai H, Siveke JT, Klein B, Mendoza-Torres L, Mazur PK, Algul H, Radtke F, Strobl L, Zimber-Strobl U, Schmid RM, Conditional ablation of Notch signaling in pancreatic development. Development. 2008 Aug;135(16):2757-65
1	J:253982 Norlin S, Parekh V, Edlund H, The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival. Development. 2018 Jan 3;145(1):dev154468
1	J:284168 Nyeng P, Heilmann S, Lof-Ohlin ZM, Pettersson NF, Hermann FM, Reynolds AB, Semb H, p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate. Dev Cell. 2019 Apr 8;49(1):31-47.e9
4*	J:309372 Padgett LR, Robertson MA, Anderson-Baucum EK, Connors CT, Wu W, Mirmira RG, Mastracci TL, Deoxyhypusine synthase, an essential enzyme for hypusine biosynthesis, is required for proper exocrine pancreas development. FASEB J. 2021 May;35(5):e21473
3	J:194063 Pan FC, Bankaitis ED, Boyer D, Xu X, Van de Casteele M, Magnuson MA, Heimberg H, Wright CV, Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration. Development. 2013 Feb;140(4):751-64
1	J:239946 Pan FC, Brissova M, Powers AC, Pfaff S, Wright CV, Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing beta-cells to a delta-like fate and reveals a facultative proliferative capacity in aged beta-cells. Development. 2015 Nov 01;142(21):3637-48
1	J:336513 Patzek S, Liu Z, de la O S, Chang S, Byrnes LE, Zhang X, Ornitz DM, Sneddon JB, Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia. iScience. 2023 Apr 21;26(4):106500
3	J:191071 Petzold KM, Naumann H, Spagnoli FM, Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas. Development. 2013 Jan 1;140(1):126-35
1	J:209016 Piccand J, Meunier A, Merle C, Jia Z, Barnier JV, Gradwohl G, Pak3 promotes cell cycle exit and differentiation of beta-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice. Diabetes. 2014 Jan;63(1):203-15
1	J:165713 Pierreux CE, Cordi S, Hick AC, Achouri Y, Ruiz de Almodovar C, Prevot PP, Courtoy PJ, Carmeliet P, Lemaigre FP, Epithelial: Endothelial cross-talk regulates exocrine differentiation in developing pancreas. Dev Biol. 2010 Nov 1;347(1):216-27
1	J:125042 Pierreux CE, Poll AV, Kemp CR, Clotman F, Maestro MA, Cordi S, Ferrer J, Leyns L, Rousseau GG, Lemaigre FP, The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology. 2006 Feb;130(2):532-41
2	J:72798 Pin CL, Rukstalis JM, Johnson C, Konieczny SF, The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity. J Cell Biol. 2001 Nov 12;155(4):519-30
2	J:315740 Prevot PP, Augereau C, Simion A, Van den Steen G, Dauguet N, Lemaigre FP, Jacquemin P, Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6. Gastroenterology. 2013 Sep;145(3):668-78.e3
1	J:251520 Pujadas G, Cervantes S, Tutusaus A, Ejarque M, Sanchez L, Garcia A, Esteban Y, Fargas L, Alsina B, Hartmann C, Gomis R, Gasa R, Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas. Sci Rep. 2016 Jan 14;6:19223
1	J:195161 Qu X, Afelik S, Jensen JN, Bukys MA, Kobberup S, Schmerr M, Xiao F, Nyeng P, Veronica Albertoni M, Grapin-Botton A, Jensen J, Notch-mediated post-translational control of Ngn3 protein stability regulates pancreatic patterning and cell fate commitment. Dev Biol. 2013 Apr 1;376(1):1-12
1	J:306082 Quilichini E, Fabre M, Nord C, Dirami T, Le Marec A, Cereghini S, Pasek RC, Gannon M, Ahlgren U, Haumaitre C, Insights into the etiology and physiopathology of MODY5/HNF1B pancreatic phenotype with a mouse model of the human disease. J Pathol. 2021 May;254(1):31-45
1	J:208938 Reinert RB, Brissova M, Shostak A, Pan FC, Poffenberger G, Cai Q, Hundemer GL, Kantz J, Thompson CS, Dai C, McGuinness OP, Powers AC, Vascular endothelial growth factor-a and islet vascularization are necessary in developing, but not adult, pancreatic islets. Diabetes. 2013 Dec;62(12):4154-64
5	J:329047 Rodriguez UA, Dahiya S, Raymond ML, Gao C, Martins-Cargill CP, Piganelli JD, Gittes GK, Hu J, Esni F, Focal adhesion kinase-mediated signaling controls the onset of pancreatic cell differentiation. Development. 2022 Sep 1;149(17):dev200761
3	J:282308 Romer AI, Singer RA, Sui L, Egli D, Sussel L, Murine Perinatal beta-Cell Proliferation and the Differentiation of Human Stem Cell-Derived Insulin-Expressing Cells Require NEUROD1. Diabetes. 2019 Dec;68(12):2259-2271
1	J:171472 Sand FW, Hornblad A, Johansson JK, Loren C, Edsbagge J, Stahlberg A, Magenheim J, Ilovich O, Mishani E, Dor Y, Ahlgren U, Semb H, Growth-limiting role of endothelial cells in endoderm development. Dev Biol. 2011 Apr 15;352(2):267-77
2	J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356
1	J:297252 Seymour PA, Collin CA, Egeskov-Madsen AR, Jorgensen MC, Shimojo H, Imayoshi I, de Lichtenberg KH, Kopan R, Kageyama R, Serup P, Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors. Dev Cell. 2020 Mar 23;52(6):731-747.e8
1*	J:218695 Soggia A, Ramond C, Akiyama H, Scharfmann R, Duvillie B, von Hippel-Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-alpha and VEGF-A upregulation. Diabetologia. 2014 Nov;57(11):2348-56
4	J:156016 Solar M, Cardalda C, Houbracken I, Martin M, Maestro MA, De Medts N, Xu X, Grau V, Heimberg H, Bouwens L, Ferrer J, Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth. Dev Cell. 2009 Dec;17(6):849-60
2	J:280517 Spaeth JM, Liu JH, Peters D, Guo M, Osipovich AB, Mohammadi F, Roy N, Bhushan A, Magnuson MA, Hebrok M, Wright CVE, Stein R, The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet beta-Cell Function. Diabetes. 2019 Sep;68(9):1806-1818
2	J:198781 Sugiyama T, Benitez CM, Ghodasara A, Liu L, McLean GW, Lee J, Blauwkamp TA, Nusse R, Wright CV, Gu G, Kim SK, Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation. Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12691-6
2	J:147764 Svensson P, Bergqvist I, Norlin S, Edlund H, MFng is dispensable for mouse pancreas development and function. Mol Cell Biol. 2009 Apr;29(8):2129-38
5	J:186391 Tao J, Zhu M, Wang H, Afelik S, Vasievich MP, Chen XW, Zhu G, Jensen J, Ginsburg D, Zhang B, SEC23B is required for the maintenance of murine professional secretory tissues. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):E2001-9
2	J:183714 Thompson N, Gesina E, Scheinert P, Bucher P, Grapin-Botton A, RNA profiling and chromatin immunoprecipitation-sequencing reveal that PTF1a stabilizes pancreas progenitor identity via the control of MNX1/HLXB9 and a network of other transcription factors. Mol Cell Biol. 2012 Mar;32(6):1189-99
1*	J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9
1	J:121610 Vanhorenbeeck V, Jenny M, Cornut JF, Gradwohl G, Lemaigre FP, Rousseau GG, Jacquemin P, Role of the Onecut transcription factors in pancreas morphogenesis and in pancreatic and enteric endocrine differentiation. Dev Biol. 2007 May 15;305(2):685-94
1	J:166759 Villasenor A, Chong DC, Henkemeyer M, Cleaver O, Epithelial dynamics of pancreatic branching morphogenesis. Development. 2010 Dec;137(24):4295-305
1	J:292264 Vinckier NK, Patel NA, Geusz RJ, Wang A, Wang J, Matta I, Harrington AR, Wortham M, Wetton N, Wang J, Jhala US, Rosenfeld MG, Benner CW, Shih HP, Sander M, LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development. Nat Commun. 2020 Apr 29;11(1):2082
1	J:119908 Wells JM, Esni F, Boivin GP, Aronow BJ, Stuart W, Combs C, Sklenka A, Leach SD, Lowy AM, Wnt/beta-catenin signaling is required for development of the exocrine pancreas. BMC Dev Biol. 2007;7:4
2	J:183127 Westmoreland JJ, Kilic G, Sartain C, Sirma S, Blain J, Rehg J, Harvey N, Sosa-Pineda B, Pancreas-specific deletion of prox1 affects development and disrupts homeostasis of the exocrine pancreas. Gastroenterology. 2012 Apr;142(4):999-1009.e6
2	J:192748 Xuan S, Borok MJ, Decker KJ, Battle MA, Duncan SA, Hale MA, Macdonald RJ, Sussel L, Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. J Clin Invest. 2012 Oct 1;122(10):3516-28
6	J:123923 Zhou Q, Law AC, Rajagopal J, Anderson WJ, Gray PA, Melton DA, A multipotent progenitor domain guides pancreatic organogenesis. Dev Cell. 2007 Jul;13(1):103-14