Gene Expression Literature Summary

• Symbol: Bdnf
• Name: brain derived neurotrophic factor
• ID: MGI:88145

115 matching records from 115 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19.5	E	P
Immunohistochemistry (section)					1				3		3		1		3	1	2	1	3		6		2	11
In situ RNA (section)				1	4	1	5	2	5		4	1	8		5		2			1	3			16
Immunohistochemistry (whole mount)																					1
In situ RNA (whole mount)											2				1						1			1
In situ reporter (knock in)			1		1		2		4		3	1	2	1			2		1	1	2			3
Northern blot		1	1	2													1			1				3
Western blot							1	1	2		4		1		3				1		2			10
RT-PCR	1				1	2	1	3	3	1	5	1	9		4	2	7	2	4		8	1	2	25

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Bdnf  brain derived neurotrophic factor
Results	Reference
1	J:82462 Agerman K, Hjerling-Leffler J, Blanchard MP, Scarfone E, Canlon B, Nosrat C, Ernfors P, BDNF gene replacement reveals multiple mechanisms for establishing neurotrophin specificity during sensory nervous system development. Development. 2003 Apr;130(8):1479-91
1*	J:81579 Aguado F, Carmona MA, Pozas E, Aguilo A, Martinez-Guijarro FJ, Alcantara S, Borrell V, Yuste R, Ibanez CF, Soriano E, BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2. Development. 2003 Apr;130(7):1267-80
3	J:160730 Alavian KN, Sgado P, Alberi L, Subramaniam S, Simon HH, Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression. Neural Dev. 2009;4:11
3	J:181188 Aoki H, Hara A, Era T, Kunisada T, Yamada Y, Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development. 2012 Feb;139(4):667-77
4	J:251150 Aoki H, Ogino H, Tomita H, Hara A, Kunisada T, Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells. PLoS One. 2016;11(9):e0163042
2	J:344220 Bai X, Wang B, Cui Y, Tian S, Zhang Y, You L, Chang YZ, Gao G, Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice. J Neuroinflammation. 2024 Jan 9;21(1):15
2	J:98945 Ballas N, Grunseich C, Lu DD, Speh JC, Mandel G, REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell. 2005 May 20;121(4):645-57
4	J:194255 Baydyuk M, Xie Y, Tessarollo L, Xu B, Midbrain-derived neurotrophins support survival of immature striatal projection neurons. J Neurosci. 2013 Feb 20;33(8):3363-9
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
3	J:65040 Botchkareva NV, Botchkarev VA, Albers KM, Metz M, Paus R, Distinct roles for nerve growth factor and brain-derived neurotrophic factor in controlling the rate of hair follicle morphogenesis. J Invest Dermatol. 2000 Feb;114(2):314-20
1	J:119559 Bouwman J, Spijker S, Schut D, Wachtler B, Ylstra B, Smit AB, Verhage M, Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. J Neurochem. 2006 Oct;99(1):84-96
2	J:164699 Breuskin I, Bodson M, Thelen N, Thiry M, Borgs L, Nguyen L, Stolt C, Wegner M, Lefebvre PP, Malgrange B, Glial but not neuronal development in the cochleo-vestibular ganglion requires Sox10. J Neurochem. 2010 Sep;114(6):1827-39
1	J:338914 Cao B, Xia Y, Cai Z, Wang Z, Tang C, Song Y, Construction of a Brain-specific SLC23A2 Gene Knockout Mice Model. Neuroscience. 2023 Aug 1;524:137-148
1*	J:83933 Cheng A, Wang S, Cai J, Rao MS, Mattson MP, Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain. Dev Biol. 2003 Jun 15;258(2):319-33
5*	J:157986 Childs AJ, Bayne RA, Murray AA, Martins Da Silva SJ, Collins CS, Spears N, Anderson RA, Differential expression and regulation by activin of the neurotrophins BDNF and NT4 during human and mouse ovarian development. Dev Dyn. 2010 Feb 19;239(4):1211-1219
4	J:74172 Chou HC, Chien CL, Lu KS, The distribution of PGP9. 5, BDNF and NGF in the vallate papilla of adult and developing mice. Anat Embryol (Berl). 2001 Aug;204(2):161-9
2*	J:93143 Clough RL, Sud R, Davis-Silberman N, Hertzano R, Avraham KB, Holley M, Dawson SJ, Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity. Biochem Biophys Res Commun. 2004 Nov 5;324(1):372-81
3	J:72304 Coppola V, Kucera J, Palko ME, Martinez-De Velasco J, Lyons WE, Fritzsch B, Tessarollo L, Dissection of NT3 functions in vivo by gene replacement strategy. Development. 2001 Nov;128(21):4315-27
1	J:40384 Craig JC, Eberwine JH, Calvin JA, Wlodarczyk B, Bennett GD, Finnell RH, Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. Biochem Mol Med. 1997 Apr;60(2):81-91
2	J:102722 Dennis KE, Levitt P, Regional expression of brain derived neurotrophic factor (BDNF) is correlated with dynamic patterns of promoter methylation in the developing mouse forebrain. Brain Res Mol Brain Res. 2005 Oct 31;140(1-2):1-9
1	J:133953 Deppmann CD, Mihalas S, Sharma N, Lonze BE, Niebur E, Ginty DD, A model for neuronal competition during development. Science. 2008 Apr 18;320(5874):369-73
1	J:108241 Desai J, Shannon ME, Johnson MD, Ruff DW, Hughes LA, Kerley MK, Carpenter DA, Johnson DK, Rinchik EM, Culiat CT, Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Hum Mol Genet. 2006 Apr 15;15(8):1329-41
1*	J:250135 Ding M, Weng C, Fan S, Cao Q, Lu Z, Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay. Front Mol Neurosci. 2017;10:121
4	J:64681 Donovan MJ, Lin MI, Wiegn P, Ringstedt T, Kraemer R, Hahn R, Wang S, Ibanez CF, Rafii S, Hempstead BL, Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization. Development. 2000 Nov;127(21):4531-40
1	J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046
1*	J:17123 Ernfors P, Lee KF, Jaenisch R, Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature. 1994 Mar 10;368(6467):147-50
4	J:337923 Esvald EE, Tuvikene J, Kiir CS, Avarlaid A, Tamberg L, Sirp A, Shubina A, Cabrera-Cabrera F, Pihlak A, Koppel I, Palm K, Timmusk T, Revisiting the expression of BDNF and its receptors in mammalian development. Front Mol Neurosci. 2023;16:1182499
2	J:253696 Feng S, Xing C, Shen T, Qiao Y, Wang R, Chen J, Liao J, Lu Z, Yang X, Abd-Allah SM, Li J, Jing N, Tang K, Abnormal Paraventricular Nucleus of Hypothalamus and Growth Retardation Associated with Loss of Nuclear Receptor Gene COUP-TFII. Sci Rep. 2017 Jul 13;7(1):5282
1	J:139608 Fox EA, Murphy MC, Factors regulating vagal sensory development: potential role in obesities of developmental origin. Physiol Behav. 2008 Apr 22;94(1):90-104
3*	J:98114 Friedman RA, Makmura L, Biesiada E, Wang X, Keithley EM, Eya1 acts upstream of Tbx1, Neurogenin 1, NeuroD and the neurotrophins BDNF and NT-3 during inner ear development. Mech Dev. 2005 May;122(5):625-34
1	J:157908 Fritzsch B, Dillard M, Lavado A, Harvey NL, Jahan I, Canal cristae growth and fiber extension to the outer hair cells of the mouse ear require Prox1 activity. PLoS One. 2010;5(2):e9377
2	J:98393 Fritzsch B, Matei VA, Nichols DH, Bermingham N, Jones K, Beisel KW, Wang VY, Atoh1 null mice show directed afferent fiber growth to undifferentiated ear sensory epithelia followed by incomplete fiber retention. Dev Dyn. 2005 Jun;233(2):570-83
2	J:323615 Fu Y, Zhou Y, Zhang YL, Zhao B, Zhang XL, Zhang WT, Lu YJ, Lu A, Zhang J, Zhang J, Loss of neurodevelopmental-associated miR-592 impairs neurogenesis and causes social interaction deficits. Cell Death Dis. 2022 Apr 1;13(4):292
1	J:214739 Glerup S, Olsen D, Vaegter CB, Gustafsen C, Sjoegaard SS, Hermey G, Kjolby M, Molgaard S, Ulrichsen M, Boggild S, Skeldal S, Fjorback AN, Nyengaard JR, Jacobsen J, Bender D, Bjarkam CR, Sorensen ES, Fuchtbauer EM, Eichele G, Madsen P, Willnow TE, Petersen CM, Nykjaer A, SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia. Neuron. 2014 Jun 4;82(5):1074-87
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2	J:88594 Guha U, Gomes WA, Samanta J, Gupta M, Rice FL, Kessler JA, Target-derived BMP signaling limits sensory neuron number and the extent of peripheral innervation in vivo. Development. 2004 Mar;131(5):1175-86
5	J:167838 Harlow DE, Yang H, Williams T, Barlow LA, Epibranchial placode-derived neurons produce BDNF required for early sensory neuron development. Dev Dyn. 2011 Feb;240(2):309-23
6	J:119779 Hertzano R, Dror AA, Montcouquiol M, Ahmed ZM, Ellsworth B, Camper S, Friedman TB, Kelley MW, Avraham KB, Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system. Eur J Neurosci. 2007 Feb;25(4):999-1005
1*	J:177585 Hesse K, Vaupel K, Kurt S, Buettner R, Kirfel J, Moser M, AP-2delta is a crucial transcriptional regulator of the posterior midbrain. PLoS One. 2011;6(8):e23483
1	J:83661 Holm PC, Rodriguez FJ, Kresse A, Canals JM, Silos-Santiago I, Arenas E, Crucial role of TrkB ligands in the survival and phenotypic differentiation of developing locus coeruleus noradrenergic neurons. Development. 2003 Aug;130(15):3535-45
3	J:276557 Hong GS, Lee SH, Lee B, Choi JH, Oh SJ, Jang Y, Hwang EM, Kim H, Jung J, Kim IB, Oh U, ANO1/TMEM16A regulates process maturation in radial glial cells in the developing brain. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12494-12499
2	J:187349 Hu XL, Cheng X, Cai L, Tan GH, Xu L, Feng XY, Lu TJ, Xiong H, Fei J, Xiong ZQ, Conditional deletion of NRSF in forebrain neurons accelerates epileptogenesis in the kindling model. Cereb Cortex. 2011 Sep;21(9):2158-65
7	J:165547 Huang T, Krimm RF, Developmental expression of Bdnf, Ntf4/5, and TrkB in the mouse peripheral taste system. Dev Dyn. 2010 Oct;239(10):2637-46
2*	J:74160 Ivanova T, Beyer C, Pre- and postnatal expression of brain-derived neurotrophic factor mRNA/protein and tyrosine protein kinase receptor B mRNA in the mouse hippocampus. Neurosci Lett. 2001 Jul 6;307(1):21-4
2	J:242970 Jahan I, Pan N, Kersigo J, Calisto LE, Morris KA, Kopecky B, Duncan JS, Beisel KW, Fritzsch B, Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival. PLoS One. 2012;7(1):e30853
1	J:178512 Jiang Y, Matevossian A, Guo Y, Akbarian S, Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice. Neuropharmacology. 2011 Jun;60(7-8):1088-97
1	J:102289 Kablar B, Belliveau AC, Presence of neurotrophic factors in skeletal muscle correlates with survival of spinal cord motor neurons. Dev Dyn. 2005 Nov;234(3):659-69
2	J:155405 Katayama K, Zine A, Ota M, Matsumoto Y, Inoue T, Fritzsch B, Aruga J, Disorganized innervation and neuronal loss in the inner ear of Slitrk6-deficient mice. PLoS One. 2009;4(11):e7786
1	J:126357 Kawamura K, Kawamura N, Fukuda J, Kumagai J, Hsueh AJ, Tanaka T, Regulation of preimplantation embryo development by brain-derived neurotrophic factor. Dev Biol. 2007 Nov 1;311(1):147-58
1*	J:246056 Khrimian L, Obri A, Ramos-Brossier M, Rousseaud A, Moriceau S, Nicot AS, Mera P, Kosmidis S, Karnavas T, Saudou F, Gao XB, Oury F, Kandel E, Karsenty G, Gpr158 mediates osteocalcin's regulation of cognition. J Exp Med. 2017 Oct 02;214(10):2859-2873
4	J:115894 Kim EY, Hong YB, Go SH, Lee B, Jung SC, Downregulation of neurotrophic factors in the brain of a mouse model of Gaucher disease; implications for neuronal loss in Gaucher disease. Exp Mol Med. 2006 Aug 31;38(4):348-56
1	J:66787 Kim WY, Fritzsch B, Serls A, Bakel LA, Huang EJ, Reichardt LF, Barth DS, Lee JE, NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development. Development. 2001 Feb;128(3):417-26
1	J:91006 Koponen E, Voikar V, Riekki R, Saarelainen T, Rauramaa T, Rauvala H, Taira T, Castren E, Transgenic mice overexpressing the full-length neurotrophin receptor trkB exhibit increased activation of the trkB-PLCgamma pathway, reduced anxiety, and facilitated learning. Mol Cell Neurosci. 2004 May;26(1):166-81
1	J:342051 Koutsioumpa C, Santiago C, Jacobs K, Lehnert BP, Barrera V, Hutchinson JN, Schmelyun D, Lehoczky JA, Paul DL, Ginty DD, Skin-type-dependent development of murine mechanosensory neurons. Dev Cell. 2023 Oct 23;58(20):2032-2047.e6
2	J:142444 Kumanogoh H, Asami J, Nakamura S, Inoue T, Balanced expression of various TrkB receptor isoforms from the Ntrk2 gene locus in the mouse nervous system. Mol Cell Neurosci. 2008 Nov;39(3):465-77
1	J:285409 Li Y, Jiao J, Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia. Sci Adv. 2020 Jan;6(1):eaay6350
1	J:285865 Liu C, Zhang L, Wu J, Sui X, Xu Y, Huang L, Han Y, Zhu H, Li Y, Sun X, Qin C, AnkG hemizygous mice present cognitive impairment and elevated anxiety/depressive-like traits associated with decreased expression of GABA receptors and postsynaptic density protein. Exp Brain Res. 2017 Nov;235(11):3375-3390
4	J:192549 Liu Y, Rutlin M, Huang S, Barrick CA, Wang F, Jones KR, Tessarollo L, Ginty DD, Sexually dimorphic BDNF signaling directs sensory innervation of the mammary gland. Science. 2012 Dec 7;338(6112):1357-60
1	J:168630 Louhivuori V, Vicario A, Uutela M, Rantamaki T, Louhivuori LM, Castren E, Tongiorgi E, Akerman KE, Castren ML, BDNF and TrkB in neuronal differentiation of Fmr1-knockout mouse. Neurobiol Dis. 2011 Feb;41(2):469-80
1*	J:310166 Lu WC, Zhou YX, Qiao P, Zheng J, Wu Q, Shen Q, The protocadherin alpha cluster is required for axon extension and myelination in the developing central nervous system. Neural Regen Res. 2018 Mar;13(3):427-433
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:98518 Mantela J, Jiang Z, Ylikoski J, Fritzsch B, Zacksenhaus E, Pirvola U, The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear. Development. 2005 May;132(10):2377-88
3	J:49747 Martinez A, Alcantara S, Borrell V, Del Rio JA, Blasi J, Otal R, Campos N, Boronat A, Barbacid M, Silos-Santiago I, Soriano E, TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections. J Neurosci. 1998 Sep 15;18(18):7336-50
2	J:102293 Matei V, Pauley S, Kaing S, Rowitch D, Beisel KW, Morris K, Feng F, Jones K, Lee J, Fritzsch B, Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit. Dev Dyn. 2005 Nov;234(3):633-50
3	J:177127 McCarthy DM, Zhang X, Darnell SB, Sangrey GR, Yanagawa Y, Sadri-Vakili G, Bhide PG, Cocaine alters BDNF expression and neuronal migration in the embryonic mouse forebrain. J Neurosci. 2011 Sep 21;31(38):13400-11
1	J:335232 McCoy ME, Kamitakahara AK, Ontogeny and Trophic Factor Sensitivity of Gastrointestinal Projecting Vagal Sensory Cell Types. eNeuro. 2023 Apr;10(4):ENEURO.0511-22.2023
1*	J:160811 McDowell KA, Hutchinson AN, Wong-Goodrich SJ, Presby MM, Su D, Rodriguiz RM, Law KC, Williams CL, Wetsel WC, West AE, Reduced cortical BDNF expression and aberrant memory in Carf knock-out mice. J Neurosci. 2010 Jun 2;30(22):7453-65
4	J:37118 McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG, Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12;384(6609):574-7
1*	J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
2	J:263867 Merk DJ, Ohli J, Merk ND, Thatikonda V, Morrissy S, Schoof M, Schmid SN, Harrison L, Filser S, Ahlfeld J, Erkek S, Raithatha K, Andreska T, Weisshaar M, Launspach M, Neumann JE, Shakarami M, Plenker D, Marra MA, Li Y, Mungall AJ, Moore RA, Ma Y, Jones SJM, Lutz B, Ertl-Wagner B, Rossi A, Wagener R, Siebert R, Jung A, Eberhart CG, Lach B, Sendtner M, Pfister SM, Taylor MD, Chavez L, Kool M, Schuller U, Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma. Dev Cell. 2018 Mar 26;44(6):709-724.e6
3	J:310877 Modarresi F, Faghihi MA, Lopez-Toledano MA, Fatemi RP, Magistri M, Brothers SP, van der Brug MP, Wahlestedt C, Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. Nat Biotechnol. 2012 Mar 25;30(5):453-9
1	J:110442 Morris JK, Maklad A, Hansen LA, Feng F, Sorensen C, Lee KF, Macklin WB, Fritzsch B, A disorganized innervation of the inner ear persists in the absence of ErbB2. Brain Res. 2006 May 26;1091(1):186-99
1	J:139366 Moses D, Drago J, Teper Y, Gantois I, Finkelstein DI, Horne MK, Fetal striatum- and ventral mesencephalon-derived expanded neurospheres rescue dopaminergic neurons in vitro and the nigro-striatal system in vivo. Neuroscience. 2008 Jun 23;154(2):606-20
2	J:21291 Musselman AC, Bennett GD, Greer KA, Eberwine JH, Finnell RH, Preliminary evidence of phenytoin-induced alterations in embryonic gene expression in a mouse model. Reprod Toxicol. 1994 Sep-Oct;8(5):383-95
3	J:57885 O'Connor R, Tessier-Lavigne M, Identification of maxillary factor, a maxillary process-derived chemoattractant for developing trigeminal sensory axons. Neuron. 1999 Sep;24(1):165-78
1	J:223933 Okubo T, Takada S, Pharyngeal arch deficiencies affect taste bud development in the circumvallate papilla with aberrant glossopharyngeal nerve formation. Dev Dyn. 2015 Jul;244(7):874-87
1	J:287361 Pakarinen E, Danilova T, Voikar V, Chmielarz P, Piepponen P, Airavaara M, Saarma M, Lindahl M, MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System. eNeuro. 2020 Jan/Feb;7(1):ENEURO.0477-19.2019
1	J:169044 Pan N, Jahan I, Kersigo J, Kopecky B, Santi P, Johnson S, Schmitz H, Fritzsch B, Conditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti. Hear Res. 2011 May;275(1-2):66-80
1	J:160265 Patel AV, Krimm RF, BDNF is required for the survival of differentiated geniculate ganglion neurons. Dev Biol. 2010 Apr 15;340(2):419-29
6	J:176574 Peng C, Aron L, Klein R, Li M, Wurst W, Prakash N, Le W, Pitx3 Is a Critical Mediator of GDNF-Induced BDNF Expression in Nigrostriatal Dopaminergic Neurons. J Neurosci. 2011 Sep 7;31(36):12802-12815
1	J:72516 Pirvola U, Spencer-Dene B, Xing-Qun L, Kettunen P, Thesleff I, Fritzsch B, Dickson C, Ylikoski J, FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis. J Neurosci. 2000 Aug 15;20(16):6125-34
1	J:328858 Poeta L, Padula A, Attianese B, Valentino M, Verrillo L, Filosa S, Shoubridge C, Barra A, Schwartz CE, Christensen J, van Bokhoven H, Helin K, Lioi MB, Collombat P, Gecz J, Altucci L, Di Schiavi E, Miano MG, Histone demethylase KDM5C is a SAHA-sensitive central hub at the crossroads of transcriptional axes involved in multiple neurodevelopmental disorders. Hum Mol Genet. 2019 Dec 15;28(24):4089-4102
1	J:184759 Quadrato G, Benevento M, Alber S, Jacob C, Floriddia EM, Nguyen T, Elnaggar MY, Pedroarena CM, Molkentin JD, Di Giovanni S, Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):E1499-508
13	J:177268 Radzikinas K, Aven L, Jiang Z, Tran T, Paez-Cortez J, Boppidi K, Lu J, Fine A, Ai X, A Shh/miR-206/BDNF Cascade Coordinates Innervation and Formation of Airway Smooth Muscle. J Neurosci. 2011 Oct 26;31(43):15407-15
2	J:93814 Reddy T, Kablar B, Evidence for the involvement of neurotrophins in muscle transdifferentiation and acetylcholine receptor transformation in the esophagus of Myf5(-/-):MyoD(-/-) and NT-3(-/-) embryos. Dev Dyn. 2004 Dec;231(4):683-92
1*	J:49433 Ringstedt T, Linnarsson S, Wagner J, Lendahl U, Kokaia Z, Arenas E, Ernfors P, Ibanez CF, BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral cortex. Neuron. 1998 Aug;21(2):305-15
4*	J:218012 Rutlin M, Ho CY, Abraira VE, Cassidy C, Woodbury CJ, Ginty DD, The cellular and molecular basis of direction selectivity of Adelta-LTMRs. Cell. 2014 Dec 18;159(7):1640-51
1	J:87385 Sadakata T, Mizoguchi A, Sato Y, Katoh-Semba R, Fukuda M, Mikoshiba K, Furuichi T, The secretory granule-associated protein CAPS2 regulates neurotrophin release and cell survival. J Neurosci. 2004 Jan 7;24(1):43-52
1	J:218838 Salvatierra J, Lee DA, Zibetti C, Duran-Moreno M, Yoo S, Newman EA, Wang H, Bedont JL, de Melo J, Miranda-Angulo AL, Gil-Perotin S, Garcia-Verdugo JM, Blackshaw S, The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation. J Neurosci. 2014 Dec 10;34(50):16809-20
1	J:187366 Shaker T, Dennis D, Kurrasch DM, Schuurmans C, Neurog1 and Neurog2 coordinately regulate development of the olfactory system. Neural Dev. 2012;7:28
1	J:198880 Shi M, Hu ZL, Zheng MH, Song NN, Huang Y, Zhao G, Han H, Ding YQ, Notch-Rbpj signaling is required for the development of noradrenergic neurons in the mouse locus coeruleus. J Cell Sci. 2012 Sep 15;125(Pt 18):4320-32
1	J:218988 Smith KM, Maragnoli ME, Phull PM, Tran KM, Choubey L, Vaccarino FM, Fgfr1 inactivation in the mouse telencephalon results in impaired maturation of interneurons expressing parvalbumin. PLoS One. 2014;9(8):e103696
2*	J:85731 Spears N, Molinek MD, Robinson LL, Fulton N, Cameron H, Shimoda K, Telfer EE, Anderson RA, Price DJ, The role of neurotrophin receptors in female germ-cell survival in mouse and human. Development. 2003 Nov;130(22):5481-91
5	J:32557 Staecker H, Van De Water TR, Lefebvre PP, Liu W, Moghadassi M, Galinovic-Schwartz V, Malgrange B, Moonen G, NGF, BDNF and NT-3 play unique roles in the in vitro development and patterning of innervation of the mammalian inner ear. Brain Res Dev Brain Res. 1996 Mar 29;92(1):49-60
3	J:106341 Stephens HE, Belliveau AC, Gupta JS, Mirkovic S, Kablar B, The role of neurotrophins in the maintenance of the spinal cord motor neurons and the dorsal root ganglia proprioceptive sensory neurons. Int J Dev Neurosci. 2005 Nov;23(7):613-20
1	J:286891 Sumi K, Uno K, Noike H, Tomohiro T, Hatanaka Y, Furukawa-Hibi Y, Nabeshima T, Miyamoto Y, Nitta A, Behavioral impairment in SHATI/NAT8L knockout mice via dysfunction of myelination development. Sci Rep. 2017 Dec 4;7(1):16872
1	J:88191 Sun W, Gould TW, Vinsant S, Prevette D, Oppenheim RW, Neuromuscular development after the prevention of naturally occurring neuronal death by Bax deletion. J Neurosci. 2003 Aug 13;23(19):7298-310
2	J:264123 Tanimizu N, Ichinohe N, Mitaka T, Intrahepatic bile ducts guide establishment of the intrahepatic nerve network in developing and regenerating mouse liver. Development. 2018 Apr 25;145(9):dev159095
1	J:28346 Taylor LE, Bennett GD, Finnell RH, Altered gene expression in murine branchial arches following in utero exposure to retinoic acid. J Craniofac Genet Dev Biol. 1995 Jan-Mar;15(1):13-25
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
7	J:340400 Tsai YY, Shen CL, D D, Tsai CY, Tarn WY, Activation of TrkB signaling mitigates cerebellar anomalies caused by Rbm4-Bdnf deficiency. Commun Biol. 2023 Sep 5;6(1):910
2	J:83510 Uchida N, Kanazawa M, Suzuki Y, Takeda M, Expression of BDNF and TrkB in mouse taste buds after denervation and in circumvallate papillae during development. Arch Histol Cytol. 2003 Mar;66(1):17-25
1	J:197621 Ueno M, Fujita Y, Tanaka T, Nakamura Y, Kikuta J, Ishii M, Yamashita T, Layer V cortical neurons require microglial support for survival during postnatal development. Nat Neurosci. 2013 May;16(5):543-51
3	J:182750 Usui N, Watanabe K, Ono K, Tomita K, Tamamaki N, Ikenaka K, Takebayashi H, Role of motoneuron-derived neurotrophin 3 in survival and axonal projection of sensory neurons during neural circuit formation. Development. 2012 Mar;139(6):1125-32
1*	J:127119 Visel A, Carson J, Oldekamp J, Warnecke M, Jakubcakova V, Zhou X, Shaw CA, Alvarez-Bolado G, Eichele G, Regulatory pathway analysis by high-throughput in situ hybridization. PLoS Genet. 2007 Oct 19;3(10):1867-83
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:167894 Vondran MW, Clinton-Luke P, Honeywell JZ, Dreyfus CF, BDNF+/- mice exhibit deficits in oligodendrocyte lineage cells of the basal forebrain. Glia. 2010 May;58(7):848-56
1*	J:221937 Watson JA, Bhattacharyya BJ, Vaden JH, Wilson JA, Icyuz M, Howard AD, Phillips E, DeSilva TM, Siegal GP, Bean AJ, King GD, Phillips SE, Miller RJ, Wilson SM, Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS. PLoS Genet. 2015 Jun;11(6):e1005290
1	J:292768 Willett RT, Bayin NS, Lee AS, Krishnamurthy A, Wojcinski A, Lao Z, Stephen D, Rosello-Diez A, Dauber-Decker KL, Orvis GD, Wu Z, Tessier-Lavigne M, Joyner AL, Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth. Elife. 2019 Nov 19;8:e50617
1	J:185531 Wu H, Lu Y, Barik A, Joseph A, Taketo MM, Xiong WC, Mei L, beta-Catenin gain of function in muscles impairs neuromuscular junction formation. Development. 2012 Jul;139(13):2392-404
3	J:173415 Wyatt SL, Spori B, Vizard TN, Davies AM, Selective regulation of nerve growth factor expression in developing cutaneous tissue by early sensory innervation. Neural Dev. 2011;6:18
1	J:266090 Xia W, Su L, Jiao J, Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress. J Cell Biol. 2018 Oct 1;217(10):3464-3479
1	J:159315 Xie Z, Ma X, Ji W, Zhou G, Lu Y, Xiang Z, Wang YX, Zhang L, Hu Y, Ding YQ, Zhang WJ, Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6510-5
1*	J:327901 Ye Q, Bhojwani A, Hu JK, Understanding the development of oral epithelial organs through single cell transcriptomic analysis. Development. 2022 Aug 15;149(16):dev200539
1	J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714