Gene Expression Literature Summary

• Symbol: Atp5f1a
• Name: ATP synthase F1 subunit alpha
• ID: MGI:88115

31 matching records from 31 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E18	E18.5	P
Immunohistochemistry (section)							1		1			2	3
In situ RNA (section)							1
Western blot	1	1	2	2	2	1	2	1	2	2		4	17
RT-PCR		1		2	2	2				1	1		4
cDNA clones				1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Atp5f1a  ATP synthase F1 subunit alpha   (Synonyms: Atp5a1, Atpm, D18Ertd206e, Mom2)
Results	Reference
1	J:303084 Alsina D, Lytovchenko O, Schab A, Atanassov I, Schober FA, Jiang M, Koolmeister C, Wedell A, Taylor RW, Wredenberg A, Larsson NG, FBXL4 deficiency increases mitochondrial removal by autophagy. EMBO Mol Med. 2020 Jul 7;12(7):e11659
2*	J:71941 Baumgart E, Vanhorebeek I, Grabenbauer M, Borgers M, Declercq PE, Fahimi HD, Baes M, Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse). Am J Pathol. 2001 Oct;159(4):1477-94
2	J:236179 Bowman CE, Zhao L, Hartung T, Wolfgang MJ, Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series. Mol Cell Biol. 2016 Aug 1;36(15):2089-104
1	J:329985 Chae SA, Son JS, de Avila JM, Du M, Zhu MJ, Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism. Am J Physiol Regul Integr Comp Physiol. 2022 Oct 3;
1	J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134
1	J:324707 Dhandapani L, Salzer MC, Duran JM, Zaffagnini G, De Guirior C, Martinez-Zamora MA, Boke E, Comparative analysis of vertebrates reveals that mouse primordial oocytes do not contain a Balbiani body. J Cell Sci. 2022 Dec 1;135(1):jcs259394
1	J:271287 Fakruddin M, Wei FY, Suzuki T, Asano K, Kaieda T, Omori A, Izumi R, Fujimura A, Kaitsuka T, Miyata K, Araki K, Oike Y, Scorrano L, Suzuki T, Tomizawa K, Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease. Cell Rep. 2018 Jan 9;22(2):482-496
2	J:284149 Fame RM, Shannon ML, Chau KF, Head JP, Lehtinen MK, A concerted metabolic shift in early forebrain alters the CSF proteome and depends on MYC downregulation for mitochondrial maturation. Development. 2019 Oct 24;146(20):dev182857
1	J:319656 Jiao X, Ma Z, Lei J, Liu P, Cai X, Shahi PK, Chan CC, Fariss R, Pattnaik BR, Dong L, Hejtmancik JF, Retinal Development and Pathophysiology in Kcnj13 Knockout Mice. Front Cell Dev Biol. 2021;9:810020
2*	J:338888 Martinez-Garza U, Choi J, Scafidi S, Wolfgang MJ, Proteomics identifies the developmental regulation of HKDC1 in liver of pigs and mice. Am J Physiol Regul Integr Comp Physiol. 2023 Aug 7;
1	J:307395 Mirra S, Garcia-Arroyo R, B Domenech E, Gavalda-Navarro A, Herrera-Ubeda C, Oliva C, Garcia-Fernandez J, Artuch R, Villarroya F, Marfany G, CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina. Neurobiol Dis. 2021 Aug;156:105405
1*	J:268424 Nakamura J, Fujikawa M, Yoshida M, IF1, a natural inhibitor of mitochondrial ATP synthase, is not essential for the normal growth and breeding of mice. Biosci Rep. 2013 Sep 17;33(5):e00067
4	J:326570 Niu W, Spradling AC, Mouse oocytes develop in cysts with the help of nurse cells. Cell. 2022 Jul 7;185(14):2576-2590.e12
1	J:236011 Odegaard JI, Lee MW, Sogawa Y, Bertholet AM, Locksley RM, Weinberg DE, Kirichok Y, Deo RC, Chawla A, Perinatal Licensing of Thermogenesis by IL-33 and ST2. Cell. 2016 Aug 11;166(4):841-54
2	J:212629 Papanicolaou KN, Kikuchi R, Ngoh GA, Coughlan KA, Dominguez I, Stanley WC, Walsh K, Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart. Circ Res. 2012 Sep 28;111(8):1012-26
2	J:337469 Park A, Kim KE, Park I, Lee SH, Park KY, Jung M, Li X, Sleiman MB, Lee SJ, Kim DS, Kim J, Lim DS, Woo EJ, Lee EW, Han BS, Oh KJ, Lee SC, Auwerx J, Mun JY, Rhee HW, Kim WK, Bae KH, Suh JM, Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice. Nat Commun. 2023 Jun 23;14(1):3746
2	J:333724 Park EJ, Kim HS, Lee DH, Kim SM, Yoon JS, Lee JM, Im SJ, Lee H, Lee MW, Lee CW, Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation. Nat Commun. 2023 Feb 25;14(1):1097
2	J:301859 Poche RA, Zhang M, Rueda EM, Tong X, McElwee ML, Wong L, Hsu CW, Dejosez M, Burns AR, Fox DA, Martin JF, Zwaka TP, Dickinson ME, RONIN Is an Essential Transcriptional Regulator of Genes Required for Mitochondrial Function in the Developing Retina. Cell Rep. 2016 Feb 23;14(7):1684-1697
1	J:198125 Rajakumari S, Wu J, Ishibashi J, Lim HW, Giang AH, Won KJ, Reed RR, Seale P, EBF2 determines and maintains brown adipocyte identity. Cell Metab. 2013 Apr 2;17(4):562-74
1	J:283318 Ruan QT, Yazdani N, Blum BC, Beierle JA, Lin W, Coelho MA, Fultz EK, Healy AF, Shahin JR, Kandola AK, Luttik KP, Zheng K, Smith NJ, Cheung J, Mortazavi F, Apicco DJ, Ragu Varman D, Ramamoorthy S, Ash PEA, Rosene DL, Emili A, Wolozin B, Szumlinski KK, Bryant CD, A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins. J Neurosci. 2020 Jan 2;40(1):107-130
1	J:270627 Sakakibara I, Wurmser M, Dos Santos M, Santolini M, Ducommun S, Davaze R, Guernec A, Sakamoto K, Maire P, Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle. Skelet Muscle. 2016;6(1):30
3	J:317550 Sakamoto T, Matsuura TR, Wan S, Ryba DM, Kim JU, Won KJ, Lai L, Petucci C, Petrenko N, Musunuru K, Vega RB, Kelly DP, A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation. Circ Res. 2020 Jun 5;126(12):1685-1702
1	J:129766 Sano M, Izumi Y, Helenius K, Asakura M, Rossi DJ, Xie M, Taffet G, Hu L, Pautler RG, Wilson CR, Boudina S, Abel ED, Taegtmeyer H, Scaglia F, Graham BH, Kralli A, Shimizu N, Tanaka H, Makela TP, Schneider MD, Menage-a-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1. Cell Metab. 2007 Feb;5(2):129-42
1*	J:249661 Schatton D, Pla-Martin D, Marx MC, Hansen H, Mourier A, Nemazanyy I, Pessia A, Zentis P, Corona T, Kondylis V, Barth E, Schauss AC, Velagapudi V, Rugarli EI, CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017 Mar 06;216(3):675-693
1	J:241230 Spitler KM, Ponce JM, Oudit GY, Hall DD, Grueter CE, Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming. Am J Physiol Heart Circ Physiol. 2017 Apr 01;312(4):H768-H780
2*	J:147173 Sultana DA, Tomita S, Hamada M, Iwanaga Y, Kitahama Y, Khang NV, Hirai S, Ohigashi I, Nitta S, Amagai T, Takahashi S, Takahama Y, Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development. Blood. 2009 Mar 26;113(13):2976-87
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
3*	J:238642 Vrbacky M, Kovalcikova J, Chawengsaksophak K, Beck IM, Mracek T, Nuskova H, Sedmera D, Papousek F, Kolar F, Sobol M, Hozak P, Sedlacek R, Houstek J, Knockout of Tmem70 alters biogenesis of ATP synthase and leads to embryonal lethality in mice. Hum Mol Genet. 2016 Nov 01;25(21):4674-4685
1	J:235644 Wu Y, Wei FY, Kawarada L, Suzuki T, Araki K, Komohara Y, Fujimura A, Kaitsuka T, Takeya M, Oike Y, Suzuki T, Tomizawa K, Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury. PLoS Genet. 2016 Sep;12(9):e1006355
10*	J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026
4	J:321836 Zhao K, Huang X, Zhao W, Lu B, Yang Z, LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development. Development. 2022 Mar 15;149(6):dev200458