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Gene Expression Literature Summary
Symbol
Name
ID
Dux
double homeobox
MGI:3703875

7 matching records from 7 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E1.5 E2 E2.5 E3.5 E7 E12 E12.5 P
Immunohistochemistry (section) 1
In situ RNA (section) 1
Immunohistochemistry (whole mount) 1
RT-PCR 4 2 1 1 1 1 1 1 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Dux  double homeobox   (Synonyms: D4Z4, Duxbl, EG664783)
Results  Reference
4*J:126165 Clapp J, Mitchell LM, Bolland DJ, Fantes J, Corcoran AE, Scotting PJ, Armour JA, Hewitt JE, Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy. Am J Hum Genet. 2007 Aug;81(2):264-79
1J:292025 Gomez-Redondo I, Ramos-Ibeas P, Pericuesta E, Fernandez-Gonzalez R, Laguna-Barraza R, Gutierrez-Adan A, Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion. Int J Mol Sci. 2020 Jun 9;21(11):4115
2*J:308830 Grow EJ, Weaver BD, Smith CM, Guo J, Stein P, Shadle SC, Hendrickson PG, Johnson NE, Butterfield RJ, Menafra R, Kloet SL, van der Maarel SM, Williams CJ, Cairns BR, p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models. Nat Genet. 2021 Aug;53(8):1207-1220
1J:287766 Ruebel ML, Vincent KA, Schall PZ, Wang K, Latham KE, SMCHD1 terminates the first embryonic genome activation event in mouse two-cell embryos and contributes to a transcriptionally repressive state. Am J Physiol Cell Physiol. 2019 Oct 1;317(4):C655-C664
3*J:285122 Sha QQ, Zhu YZ, Li S, Jiang Y, Chen L, Sun XH, Shen L, Ou XH, Fan HY, Characterization of zygotic genome activation-dependent maternal mRNA clearance in mouse. Nucleic Acids Res. 2020 Jan 24;48(2):879-894
1J:299538 Suliman-Lavie R, Title B, Cohen Y, Hamada N, Tal M, Tal N, Monderer-Rothkoff G, Gudmundsdottir B, Gudmundsson KO, Keller JR, Huang GJ, Nagata KI, Yarom Y, Shifman S, Pogz deficiency leads to transcription dysregulation and impaired cerebellar activity underlying autism-like behavior in mice. Nat Commun. 2020 Nov 17;11(1):5836
6J:333801 Zhang X, Zhang C, Zhou D, Zhang T, Chen X, Ren J, He C, Meng F, Zhou Q, Yang Q, Dai C, Lin G, Zeng S, Leng L, Telomeres cooperate in zygotic genome activation by affecting DUX4/Dux transcription. iScience. 2023 Mar 17;26(3):106158

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory