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Gene Expression Literature Summary
Symbol
Name
ID
Chsy1
chondroitin sulfate synthase 1
MGI:2681120

7 matching records from 7 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E13 E13.5 E14 E14.5 E15.5 E16 E16.5 E18.5 P
Immunohistochemistry (section) 1 1 1
In situ RNA (section) 1 1 2 1
RT-PCR 1 1 1 2 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Chsy1  chondroitin sulfate synthase 1   (Synonyms: mKIAA0990, skt)
Results  Reference
1J:297362 Bachvarova V, Dierker T, Esko J, Hoffmann D, Kjellen L, Vortkamp A, Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate. Matrix Biol. 2020 Nov;93:43-59
4J:339242 Hu B, Lv X, Wei L, Wang Y, Zheng G, Yang C, Zang F, Wang J, Li J, Wu X, Yue Z, Xiao Q, Shao Z, Yuan W, Li J, Cao P, Xu C, Chen H, Sensory Nerve Maintains Intervertebral Disc Extracellular Matrix Homeostasis Via CGRP/CHSY1 Axis. Adv Sci (Weinh). 2022 Oct;9(30):e2202620
2*J:120970 Sakai K, Kimata K, Sato T, Gotoh M, Narimatsu H, Shinomiya K, Watanabe H, Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage. J Biol Chem. 2007 Feb 9;282(6):4152-61
1*J:256718 Shimbo M, Suzuki R, Fuseya S, Sato T, Kiyohara K, Hagiwara K, Okada R, Wakui H, Tsunakawa Y, Watanabe H, Kimata K, Narimatsu H, Kudo T, Takahashi S, Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2. PLoS One. 2017;12(12):e0190333
3J:283457 Uijtdewilligen PJE, Versteeg EM, van de Westerlo EMA, van der Vlag J, Daamen WF, van Kuppevelt TH, Dynamic Expression of Genes Involved in Proteoglycan/Glycosaminoglycan Metabolism during Skin Development. Biomed Res Int. 2018;2018:9873471
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
3J:182757 Wilson DG, Phamluong K, Lin WY, Barck K, Carano RA, Diehl L, Peterson AS, Martin F, Solloway MJ, Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning. Dev Biol. 2012 Mar 15;363(2):413-25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory