Gene Expression Literature Summary

• Symbol: Mir126a
• Name: microRNA 126a
• ID: MGI:2676811

21 matching records from 21 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E8.5	E9.5	E10.5	E11.5	E12	E12.5	E13.5	E14.5	E15	E16.5	E17	E17.5	E18.5	E	P
In situ RNA (section)					1	1	1		1			3					1		1
In situ RNA (whole mount)						1	2
Northern blot																			1
RT-PCR	1	1	1	1			2	2		3	2	1	1	2	1	1	1	1	8

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mir126a  microRNA 126a   (Synonyms: Mirn126, mmu-mir-126, mmu-mir-126a)
Results	Reference
2*	J:165521 Aguilar AL, Piskol R, Beitzinger M, Zhu JY, Kruspe D, Aszodi A, Moser M, Englert C, Meister G, The small RNA expression profile of the developing murine urinary and reproductive systems. FEBS Lett. 2010 Nov 5;584(21):4426-34
3*	J:152495 Carraro G, El-Hashash A, Guidolin D, Tiozzo C, Turcatel G, Young BM, De Langhe SP, Bellusci S, Shi W, Parnigotto PP, Warburton D, miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev Biol. 2009 Sep 15;333(2):238-50
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3	J:138346 Dogini DB, Ribeiro PA, Rocha C, Pereira TC, Lopes-Cendes I, MicroRNA expression profile in murine central nervous system development. J Mol Neurosci. 2008 Jul;35(3):331-7
1	J:182447 Jiang Z, Yu N, Kuang P, Chen M, Shao F, Martin G, Chui DH, Cardoso WV, Ai X, Lu J, Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm. J Biol Chem. 2012 Feb 17;287(8):5979-87
2*	J:112756 Kloosterman WP, Wienholds E, de Bruijn E, Kauppinen S, Plasterk RH, In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes. Nat Methods. 2006 Jan;3(1):27-9
1	J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400
2	J:143206 Kuhnert F, Mancuso MR, Hampton J, Stankunas K, Asano T, Chen CZ, Kuo CJ, Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126. Development. 2008 Dec;135(24):3989-93
2	J:242904 Lacko LA, Hurtado R, Hinds S, Poulos MG, Butler JM, Stuhlmann H, Altered feto-placental vascularization, feto-placental malperfusion and fetal growth restriction in mice with Egfl7 loss of function. Development. 2017 Jul 01;144(13):2469-2479
1	J:183008 Li Y, Taketo T, Lau YF, Isolation of fetal gonads from embryos of timed-pregnant mice for morphological and molecular studies. Methods Mol Biol. 2012;825:3-16
1	J:284120 Mahamud MR, Geng X, Ho YC, Cha B, Kim Y, Ma J, Chen L, Myers G, Camper S, Mustacich D, Witte M, Choi D, Hong YK, Chen H, Varshney G, Engel JD, Wang S, Kim TH, Lim KC, Srinivasan RS, GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development. 2019 Nov 5;146(21):dev184218
2	J:167379 Nichol D, Shawber C, Fitch MJ, Bambino K, Sharma A, Kitajewski J, Stuhlmann H, Impaired angiogenesis and altered Notch signaling in mice overexpressing endothelial Egfl7. Blood. 2010 Dec 23;116(26):6133-43
2*	J:173488 Pandey P, Qin S, Ho J, Zhou J, Kreidberg JA, Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease. BMC Syst Biol. 2011;5:56
1	J:273075 Phua YL, Chu JY, Marrone AK, Bodnar AJ, Sims-Lucas S, Ho J, Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival. Physiol Rep. 2015 Oct;3(10)
3	J:258494 Poissonnier L, Villain G, Soncin F, Mattot V, miR126-5p repression of ALCAM and SetD5 in endothelial cells regulates leucocyte adhesion and transmigration. Cardiovasc Res. 2014 Jun 1;102(3):436-47
2*	J:203846 Real FM, Sekido R, Lupianez DG, Lovell-Badge R, Jimenez R, Burgos M, A microRNA (mmu-miR-124) prevents Sox9 expression in developing mouse ovarian cells. Biol Reprod. 2013 Oct;89(4):78
1	J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775
5	J:119483 Tang F, Kaneda M, O'Carroll D, Hajkova P, Barton SC, Sun YA, Lee C, Tarakhovsky A, Lao K, Surani MA, Maternal microRNAs are essential for mouse zygotic development. Genes Dev. 2007 Mar 15;21(6):644-8
4	J:139708 Wang S, Aurora AB, Johnson BA, Qi X, McAnally J, Hill JA, Richardson JA, Bassel-Duby R, Olson EN, The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis. Dev Cell. 2008 Aug;15(2):261-71
2*	J:254918 Yang J, Joshi S, Wang Q, Li P, Wang H, Xiong Y, Xiao Y, Wang J, Parker-Thornburg J, Behringer RR, Yu D, 14-3-3zeta loss leads to neonatal lethality by microRNA-126 downregulation-mediated developmental defects in lung vasculature. Cell Biosci. 2017;7:58
1	J:290155 Zhuang P, Zhang H, Welchko RM, Thompson RC, Xu S, Turner DL, Combined microRNA and mRNA detection in mammalian retinas by in situ hybridization chain reaction. Sci Rep. 2020 Jan 15;10(1):351