Gene Expression Literature Summary

• Symbol: Trpm8
• Name: transient receptor potential cation channel, subfamily M, member 8
• ID: MGI:2181435

24 matching records from 24 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E10.5	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	P
Immunohistochemistry (section)							1			1			1	1			2
In situ RNA (section)	1	1			1	1	1					3		1	1	2	13
Western blot																	1
RT-PCR		1	1	1	1			1	2	1	1	1	1		2	1	7
cDNA clones																	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Trpm8  transient receptor potential cation channel, subfamily M, member 8   (Synonyms: CMR1, Trp-p8, TRPP8)
Results	Reference
3*	J:161879 Asai Y, Holt JR, Geleoc GS, A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea. J Assoc Res Otolaryngol. 2010 Mar;11(1):27-37
3	J:106971 Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q, Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron. 2006 Feb 2;49(3):365-77
1	J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400
6	J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014
1*	J:308929 De Vincenti AP, Alsina FC, Ferrero Restelli F, Hedman H, Ledda F, Paratcha G, Lrig1 and Lrig3 cooperate to control Ret receptor signaling, sensory axonal growth and epidermal innervation. Development. 2021 Aug 15;148(16):dev197020
1	J:283226 Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ, Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019 Mar 26;26(13):3522-3536.e5
1	J:160718 Dykes IM, Lanier J, Eng SR, Turner EE, Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation. Neural Dev. 2010;5:3
1	J:210892 Gorokhova S, Gaillard S, Urien L, Malapert P, Legha W, Baronian G, Desvignes JP, Alonso S, Moqrich A, Uncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptor. PLoS Genet. 2014 Feb;10(2):e1004081
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:304297 Landy MA, Goyal M, Casey KM, Liu C, Lai HC, Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation. Cell Rep. 2021 Mar 30;34(13):108913
3	J:148796 Lechner SG, Frenzel H, Wang R, Lewin GR, Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development. EMBO J. 2009 May 20;28(10):1479-91
1	J:285409 Li Y, Jiao J, Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia. Sci Adv. 2020 Jan;6(1):eaay6350
2*	J:186470 Lopes C, Liu Z, Xu Y, Ma Q, Tlx3 and runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11;32(28):9706-15
1	J:221586 Lou S, Pan X, Huang T, Duan B, Yang FC, Yang J, Xiong M, Liu Y, Ma Q, Incoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptors. J Neurosci. 2015 Apr 1;35(13):5317-29
1*	J:126484 Luo W, Wickramasinghe SR, Savitt JM, Griffin JW, Dawson TM, Ginty DD, A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. Neuron. 2007 Jun 7;54(5):739-54
2	J:76188 Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, Patapoutian A, A TRP channel that senses cold stimuli and menthol. Cell. 2002 Mar 8;108(5):705-15
3*	J:225328 Ren AJ, Wang K, Zhang H, Liu A, Ma X, Liang Q, Cao D, Wood JN, He DZ, Ding YQ, Yuan WJ, Xie Z, Zhang WJ, ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons. Nat Commun. 2014;5:4984
1	J:327897 Rios AS, Paula De Vincenti A, Casadei M, Aquino JB, Brumovsky PR, Paratcha G, Ledda F, Etv4 regulates nociception by controlling peptidergic sensory neuron development and peripheral tissue innervation. Development. 2022 Aug 15;149(16):dev200583
6	J:159386 Shibasaki K, Murayama N, Ono K, Ishizaki Y, Tominaga M, TRPV2 enhances axon outgrowth through its activation by membrane stretch in developing sensory and motor neurons. J Neurosci. 2010 Mar 31;30(13):4601-12
7*	J:155900 Staaf S, Franck MC, Marmigere F, Mattsson JP, Ernfors P, Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons. Gene Expr Patterns. 2010 Jan;10(1):65-74
4	J:95250 Tamura S, Morikawa Y, Senba E, TRPV2, a capsaicin receptor homologue, is expressed predominantly in the neurotrophin-3-dependent subpopulation of primary sensory neurons. Neuroscience. 2005;130(1):223-8
1	J:299610 Venteo S, Desiderio S, Cabochette P, Deslys A, Carroll P, Pattyn A, Neurog2 Deficiency Uncovers a Critical Period of Cell Fate Plasticity and Vulnerability among Neural-Crest-Derived Somatosensory Progenitors. Cell Rep. 2019 Dec 3;29(10):2953-2960.e2
1	J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45
1	J:266090 Xia W, Su L, Jiao J, Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress. J Cell Biol. 2018 Oct 1;217(10):3464-3479