Gene Expression Literature Summary

• Symbol: Pofut1
• Name: protein O-fucosyltransferase 1
• ID: MGI:2153207

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E4.5	E5.5	E6.5	E7.5	E8.5	E9	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E18.5	E20	P
Immunohistochemistry (section)										1				1
In situ RNA (section)									1		1		1			1		1
In situ RNA (whole mount)						1	2		1
Northern blot	1	1	1	1	1		2	2	2	2	1	1	1	1	1	1		1
Western blot					1		2						1		1		1	1
RT-PCR			1		1		1	1	2			2	1	1				3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pofut1  protein O-fucosyltransferase 1   (Synonyms: O-FucT-1)
Results	Reference
4	J:251458 Ajima R, Suzuki E, Saga Y, Pofut1 point-mutations that disrupt O-fucosyltransferase activity destabilize the protein and abolish Notch1 signaling during mouse somitogenesis. PLoS One. 2017;12(11):e0187248
7*	J:142424 Kim ML, Chandrasekharan K, Glass M, Shi S, Stahl MC, Kaspar B, Stanley P, Martin PT, O-fucosylation of muscle agrin determines its ability to cluster acetylcholine receptors. Mol Cell Neurosci. 2008 Nov;39(3):452-64
1	J:185603 Li S, Wang Y, Zhang Y, Lu MM, Demayo FJ, Dekker JD, Tucker PW, Morrisey EE, Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2. Development. 2012 Jul;139(14):2500-9
4	J:145608 Schuster-Gossler K, Harris B, Johnson KR, Serth J, Gossler A, Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development. BMC Dev Biol. 2009;9:6
11*	J:102175 Shi S, Stahl M, Lu L, Stanley P, Canonical Notch signaling is dispensable for early cell fate specifications in mammals. Mol Cell Biol. 2005 Nov;25(21):9503-8
13	J:83299 Shi S, Stanley P, Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5234-9
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
2	J:150051 Tsao PN, Vasconcelos M, Izvolsky KI, Qian J, Lu J, Cardoso WV, Notch signaling controls the balance of ciliated and secretory cell fates in developing airways. Development. 2009 Jul;136(13):2297-307
1	J:175774 Tsao PN, Wei SC, Wu MF, Huang MT, Lin HY, Lee MC, Lin KM, Wang IJ, Kaartinen V, Yang LT, Cardoso WV, Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development. Development. 2011 Aug;138(16):3533-43
3	J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578